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Understanding sarcopenia as a geriatric syndrome

Cruz-Jentoft, Alfonso J.
Landi, Francesco
Topinkova, Eva
Published in Current Opinion in Clinical Nutrition and Metabolic Care. 2010, vol. 13, no. 1, p. 1-7
Abstract PURPOSE OF REVIEW: Highly prevalent in the population older than 65 years and leading to poor outcomes (functional decline and its related consequences), sarcopenia does not benefit yet either of a clear understanding of its pathophysiology or of precise clinical or biological markers allowing its identification. RECENT FINDINGS: The new scientific definition of 'geriatric syndromes' challenges the authors to review the current sarcopenia literature, allowing them to affirm that sarcopenia cannot be considered as an age-related disease but as a true 'geriatric syndrome'. More than 50% of the population older than 80 years suffer from this medical condition, which is linked to multiple causations: the ageing process itself, genetic susceptibility, certain life habits, changes in living conditions and a number of chronic diseases. Moreover, sarcopenia favours poor outcomes such as mobility disorders, disability, poor quality of life and death. SUMMARY: Considering sarcopenia as a geriatric syndrome allows us to request its recognition and assess its multiple risk factors, to implement a clinical and public health approach to the management of sarcopenic patients and population at risk and to disentangle the links among sarcopenia, frailty, disability and mortality.
Keywords Aged*GeriatricsHumansRisk Factors*Sarcopenia/diagnosis/epidemiology/etiology
PMID: 19915458
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CRUZ-JENTOFT, Alfonso J. et al. Understanding sarcopenia as a geriatric syndrome. In: Current Opinion in Clinical Nutrition and Metabolic Care, 2010, vol. 13, n° 1, p. 1-7. doi: 10.1097/MCO.0b013e328333c1c1 https://archive-ouverte.unige.ch/unige:20862

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Deposited on : 2012-05-23

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