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Scientific Article - Review
unige:20796 
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Diagnosis of venous thromboembolism: an update |
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| Authors | ||
| Published in | Vascular Medicine. 2010, vol. 15, no. 5, p. 399-406 | |
| Abstract | Deep vein thrombosis (DVT) and pulmonary embolism (PE) cannot be diagnosed solely on a clinical basis owing to the lack of sensitivity and specificity of clinical signs and symptoms. Phlebography and pulmonary angiography are invasive and resource-demanding imaging modalities. Because the prevalence of DVT and PE is relatively low (typically 20% or less) among clinically suspected individuals, submitting all of them to imaging would not be cost-effective. Therefore, non-invasive diagnostic algorithms have been developed that include clinical probability assessment and D-dimer measurement. These initial steps allow the selection of patients who require non-invasive imaging: compression ultrasonography in cases of suspected DVT and multidetector computed tomography (CT) angiography in cases of suspected PE. This review gives a critical appraisal of the sequential steps of the diagnostic work-up in suspected DVT or PE. | |
| Keywords | Age Factors — Algorithms — Biological Markers/blood — Fibrin Fibrinogen Degradation Products/analysis — Humans — Magnetic Resonance Angiography — Predictive Value of Tests — Prognosis — Pulmonary Embolism/*diagnosis/therapy — Risk Assessment — Risk Factors — Tomography, X-Ray Computed — Ultrasonography — Venous Thromboembolism/*diagnosis/therapy — Venous Thrombosis/*diagnosis/therapy | |
| Identifiers | PMID: 20926499 | |
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| Research groups | Geneva Platelet Group (13) Groupe Perrier Arnaud (Médecine interne générale, de réhabilitation et de gériatrie) (585) La maladie thromboembolique veineuse (808) | |
| Citation (ISO format) | BOUNAMEAUX, Henri, PERRIER, Arnaud, RIGHINI, Marc Philip. Diagnosis of venous thromboembolism: an update. In: Vascular Medicine, 2010, vol. 15, n° 5, p. 399-406. https://archive-ouverte.unige.ch/unige:20796 |
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