en
Scientific article
Review
French

Atteintes médicamenteuses du tractus gastro-intestinal: une revue clinico-pathologique

Other titleDrug-induced injury in the gastrointestinal tract: a clinico-pathological review
Published inRevue médicale suisse, vol. 6, no. 261, p. 1650-1655
Publication date2010
Abstract

Many drugs are known to have adverse effects on the gastrointestinal tract. The consequences can range from asymptomatic histological lesions in the gastrointestinal mucosa to fatal complications such as haemorrhage or perforation. On the biopsies (or on surgical specimens), there is a limited number of injury pattern that should suggest drug-induced pathology. They are mostly non specific (ex: ulcer). However, some drugs may induce pathognomonic histological lesions. For this reason, the diagnosis of a drug-induced gastrointestinal pathology depends on a clinicopathological correlation and implies a good communication between the pathologist and the clinician. In this review, we focus on the most common and well-described drug-related clinico-pathological conditions of the gastrointestinal tract using an organ and lesion based approach.

Keywords
  • Apoptosis/drug effects
  • Colitis/chemically induced/pathology
  • Duodenal Ulcer/chemically induced/pathology
  • Eosinophils
  • Esophagitis/chemically induced/pathology
  • Gastrointestinal Diseases/*chemically induced/*pathology
  • Gastrointestinal Tract/*drug effects/*pathology
  • Humans
  • Intestinal Mucosa/drug effects/pathology
  • Severity of Illness Index
  • Stomach Ulcer/chemically induced/pathology
Citation (ISO format)
PUSZTASZERI, Marc et al. Atteintes médicamenteuses du tractus gastro-intestinal: une revue clinico-pathologique. In: Revue médicale suisse, 2010, vol. 6, n° 261, p. 1650–1655.
Identifiers
ISSN of the journal1660-9379
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