Androgen replacement therapy improves function in male rat muscles independently of hypertrophy and activation of the Akt/mTOR pathway
Contributeurs/tricesHourde, C.; Jagerschmidt, C.; Clement-Lacroix, P.; Vignaud, A.; Ammann, Patrick; Butler-Browne, G. S.; Ferry, A.
Publié dansActa physiologica, vol. 195, no. 4, p. 471-482
Date de publication2009
Résumé
Mots-clés
- Anabolic Agents/therapeutic use
- Androgens/*therapeutic use
- Animals
- Bone Density/drug effects
- Citrate (si)-Synthase/metabolism
- Dihydrotestosterone/therapeutic use
- *Hormone Replacement Therapy
- Hypertrophy
- Intracellular Signaling Peptides and Proteins/*metabolism
- Male
- Muscle, Skeletal/*drug effects/*pathology/physiopathology
- Muscular Diseases/*drug therapy/*physiopathology
- Myosin Heavy Chains/metabolism
- Nandrolone/analogs & derivatives/therapeutic use
- Oncogene Protein v-akt/*metabolism
- Orchiectomy
- Protein-Serine-Threonine Kinases/*metabolism
- Rats
- TOR Serine-Threonine Kinases
- Tibia/drug effects/metabolism/pathology
Groupe de recherche
Citation (format ISO)
HOURDE, C. et al. Androgen replacement therapy improves function in male rat muscles independently of hypertrophy and activation of the Akt/mTOR pathway. In: Acta physiologica, 2009, vol. 195, n° 4, p. 471–482. doi: 10.1111/j.1748-1716.2008.01902.x
Fichiers principaux (1)
Article
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Identifiants
- PID : unige:19863
- DOI : 10.1111/j.1748-1716.2008.01902.x
- PMID : 18801052
ISSN du journal1748-1708