Scientific article

The "rut metaphor": a conceptualization of attractor-shaping properties of addictive drugs

Published inSubstance use & misuse, vol. 43, no. 3-4, p. 469-479
Publication date2008

The development of nonlinear models might yield better insight into the dynamics of substance use-related disorders than linear models. Nonlinear modelizations are, however, not always easily intelligible. A metaphor is presented illustrating a nonlinear conceptualization of the development of drug addiction based on recent findings on neural plasticity. Ruts are described as correlates of especially strong mnesic traces, which function as attractors, and hegemonize cognitions and behavior toward drug use. Dopaminergic activity of addictive drugs is proposed to represent the weight of vehicles tracing ruts.

  • Behavior, Addictive/*metabolism/*psychology
  • Brain/*metabolism
  • Glutamic Acid/metabolism
  • Humans
  • Long-Term Potentiation
  • Receptors, AMPA/metabolism
  • Receptors, N-Methyl-D-Aspartate/metabolism
  • Substance-Related Disorders/*metabolism/*psychology
Citation (ISO format)
ZULLINO, Daniele Fabio, KHAZAAL, Yasser. The ‘rut metaphor’: a conceptualization of attractor-shaping properties of addictive drugs. In: Substance use & misuse, 2008, vol. 43, n° 3-4, p. 469–479. doi: 10.1080/10826080701205042
Updates (1)
ISSN of the journal1082-6084

Technical informations

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