en
Scientific article
Review
English

New(s) to the (Z-)ring

Published inCurrent opinion in microbiology, vol. 14, no. 6, p. 691-697
Publication date2011
Abstract

Cytokinesis in bacteria is mediated by a macromolecular machine known as the divisome, consisting of an assembly of FtsZ polymers around the cylindrical axis of the cell and the downstream regulators of division that are subsequently recruited to it. FtsZ polymerizes into filaments in a GTP-dependent manner, similarly to its eukaryotic structural homolog tubulin. The initial placement of the FtsZ polymerization site is tightly regulated by multiple mechanisms, as are the subsequent polymer reshaping and force generation that separate the two daughter cells from each other. New factors have been recently discovered that contribute to this regulation, notably affecting FtsZ polymer shaping, and modulating FtsZ polymerization in response to the metabolic or redox state of the cell.

Citation (ISO format)
KIRKPATRICK, Clare, VIOLLIER, Patrick. New(s) to the (Z-)ring. In: Current opinion in microbiology, 2011, vol. 14, n° 6, p. 691–697. doi: 10.1016/j.mib.2011.09.011
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal1369-5274
495views
1downloads

Technical informations

Creation01/27/2012 9:13:00 PM
First validation01/27/2012 9:13:00 PM
Update time03/14/2023 5:08:16 PM
Status update03/14/2023 5:08:16 PM
Last indexation05/02/2024 12:11:52 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack