Scientific article
OA Policy
English

Risk factors for measles mortality and the importance of decentralized case management during an unusually large measles epidemic in eastern Democratic Republic of Congo in 2013

Published inPloS one, vol. 13, no. 3, e0194276
Publication date2018-03-14
First online date2018-03-14
Abstract

In 2013, a large measles epidemic occurred in the Aketi Health Zone of the Democratic Republic of Congo. We conducted a two-stage, retrospective cluster survey to estimate the attack rate, the case fatality rate, and the measles-specific mortality rate during the epidemic. 1424 households containing 7880 individuals were included. The estimated attack rate was 14.0%, (35.0% among children aged <5 years). The estimated case fatality rate was 4.2% (6.1% among children aged <5 years). Spatial analysis and linear regression showed that younger children, those who did not receive care, and those living farther away from Aketi Hospital early in the epidemic had a higher risk of measles related death. Vaccination coverage prior to the outbreak was low (76%), and a delayed reactive vaccination campaign contributed to the high attack rate. We provide evidences suggesting that a comprehensive case management approach reduced measles fatality during this epidemic in rural, inaccessible resource-poor setting.

Affiliation entities Not a UNIGE publication
Citation (ISO format)
GIGNOUX, Etienne et al. Risk factors for measles mortality and the importance of decentralized case management during an unusually large measles epidemic in eastern Democratic Republic of Congo in 2013. In: PloS one, 2018, vol. 13, n° 3, p. e0194276. doi: 10.1371/journal.pone.0194276
Main files (1)
Article (Published version)
Identifiers
Additional URL for this publicationhttps://dx.plos.org/10.1371/journal.pone.0194276
Journal ISSN1932-6203
38views
16downloads

Technical informations

Creation29/05/2024 10:16:33
First validation17/07/2024 10:55:21
Update time17/07/2024 10:55:21
Status update17/07/2024 10:55:21
Last indexation01/11/2024 11:20:51
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack