Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1
Publié dansNature communications, vol. 14, no. 1, 3893
Date de publication2023-07-01
Date de mise en ligne2023-07-01
Résumé
Mots-clés
- Protein Domains
- Proteolysis
- Antineoplastic Agents
- Hedhegog Proteins
- Proteolysis Targeting Chimera
Financement
- Swiss National Science Foundation - Deciphering and Targeting the Cancer Ubiquitylome [186405]
- Swiss National Science Foundation - Inhibitors of cilia and Hedgehog signaling: from phenotype to mechanistic understanding [189246]
- Swiss National Science Foundation - Epigenome editing to study chromatin remodeling during brain development [194305]
Citation (format ISO)
BAGKA, Meropi et al. Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1. In: Nature communications, 2023, vol. 14, n° 1, p. 3893. doi: 10.1038/s41467-023-39657-1
Fichiers principaux (1)
Article (Published version)
Fichiers secondaires (5)
Identifiants
- PID : unige:176793
- DOI : 10.1038/s41467-023-39657-1
- PMID : 37393376
URL commercialhttps://www.nature.com/articles/s41467-023-39657-1
ISSN du journal2041-1723