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Fibrose pulmonaire et cancer pulmonaire  : entre complémentarités et spécificités

Published inRevue médicale suisse, vol. 18, no. 804, p. 2162-2168
Publication date2022-11-16
Abstract

Lung cancer is the leading cause of cancer mortality in the developed world. Diffuse fibrosing interstitial lung disease (ILD) consist of a heterogeneous group that includes idiopathic pulmonary fibrosis (IPF). Diffuse ILD is a risk factor for the development of lung cancer which on its own is associated with an increased risk of morbidity and mortality. Despite common mechanisms between fibrogenesis and carcinogenesis, the underlying pathogenesis of lung cancer and fibrosis overlap is poorly understood. The clinical management of these patients remains a medical challenge requiring a multidisciplinary approach, particularly in view of the risk of acute exacerbation of fibrosing ILD following most lung cancer treatments, leading to a considerable negative outcome on overall prognosis.

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Keywords
  • Humans
  • Lung Diseases, Interstitial
  • Idiopathic Pulmonary Fibrosis / etiology
  • Idiopathic Pulmonary Fibrosis / therapy
  • Lung / pathology
  • Lung Neoplasms / complications
  • Prognosis
  • Disease Progression
Citation (ISO format)
REY COBO, Juliana et al. Fibrose pulmonaire et cancer pulmonaire  : entre complémentarités et spécificités. In: Revue médicale suisse, 2022, vol. 18, n° 804, p. 2162–2168. doi: 10.53738/REVMED.2022.18.804.2162
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ISSN of the journal1660-9379
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