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Health-care workers: source, vector, or victim of MRSA?

Albrich, Werner C.
Published in The Lancet Infectious Diseases. 2008, vol. 8, no. 5, p. 289-301
Abstract There is ongoing controversy about the role of health-care workers in transmission of meticillin-resistant Staphylococcus aureus (MRSA). We did a search of the literature from January, 1980, to March, 2006, to determine the likelihood of MRSA colonisation and infection in health-care workers and to assess their role in MRSA transmission. In 127 investigations, the average MRSA carriage rate among 33 318 screened health-care workers was 4.6%; 5.1% had clinical infections. Risk factors included chronic skin diseases, poor hygiene practices, and having worked in countries with endemic MRSA. Both transiently and persistently colonised health-care workers were responsible for several MRSA clusters. Transmission from personnel to patients was likely in 63 (93%) of 68 studies that undertook genotyping. MRSA eradication was achieved in 449 (88%) of 510 health-care workers. Subclinical infections and colonisation of extranasal sites were associated with persistent carriage. We discuss advantages and disadvantages of screening and eradication policies for MRSA control and give recommendations for the management of colonised health-care workers in different settings.
Keywords Carrier StateCross Infection/epidemiology/prevention & control/transmissionFemaleHealth PersonnelHumansHygieneInfectious Disease Transmission, Professional-to-PatientMaleMethicillin ResistancePrevalenceRisk FactorsStaphylococcal Infections/epidemiology/prevention & control/transmissionStaphylococcus aureus/drug effects/isolation & purification
PMID: 18471774
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Research group Groupe Harbarth Stephan (Staphylocoques dorés résistants à la méthicilline) (866)
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ALBRICH, Werner C., HARBARTH, Stéphan Juergen. Health-care workers: source, vector, or victim of MRSA?. In: The Lancet Infectious Diseases, 2008, vol. 8, n° 5, p. 289-301. doi: 10.1016/S1473-3099(08)70097-5 https://archive-ouverte.unige.ch/unige:1705

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Deposited on : 2009-05-25

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