en
Scientific article
English

I can't get it off my mind: Attentional bias in former and current cocaine addiction

Published inJournal of psychopharmacology, vol. 34, no. 11, 1218-1225
Publication date2020-11
First online date2020-08-25
Abstract

Background: Cocaine addiction is a global health issue with limited therapeutic options and a high relapse rate. Attentional bias towards substance-related cues may be an important factor for relapse. However, it has never been compared in former and current cocaine-dependent patients.

Methods: Attentional bias towards cocaine-related words was assessed using an emotional Stroop task in cocaine-dependent patients (N = 40), long-term abstinent former cocaine-dependent patients (N = 24; mean abstinence: 2 years) and control subjects (N = 28). Participants had to name the colour of cocaine-related words, neutral words and colour names. We assessed response times using an automatic voice-onset detection method we developed and we measured attentional bias as the difference in response times between cocaine-related and neutral conditions.

Results: There was an overall group effect on attentional bias towards cocaine, but no group effect on the colour Stroop effect. Two-by-two comparison showed a difference in attentional bias between cocaine-dependent patients and controls, whereas long-term abstinent former cocaine-dependent patients were not different from either. Although cocaine-dependent patients showed a significant attentional bias, consistent with the literature, neither long-term abstinent former cocaine-dependent patients nor controls showed a significant attentional bias towards cocaine-related words. We found no link between attentional bias size and either addiction severity or craving.

Conclusions: Cocaine abstinence was associated with an absence of significant attentional bias towards cocaine-related words, which may be interpreted either as an absence of attentional bias predicting success in maintaining abstinence, or as attentional bias being able to disappear with long-term cocaine abstinence. Further research is needed to distinguish the role of attentional bias in maintaining abstinence.

eng
Keywords
  • Cocaine addiction
  • Stroop task
  • Addiction recovery
  • Attentional bias
  • Adult
  • Affect / physiology
  • Aged
  • Attentional Bias / physiology
  • Cocaine-Related Disorders / physiopathology
  • Cues
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psychomotor Performance / physiology
  • Stroop Test
  • Young Adult
Citation (ISO format)
SMITH, Pauline et al. I can’t get it off my mind: Attentional bias in former and current cocaine addiction. In: Journal of psychopharmacology, 2020, vol. 34, n° 11, p. 1218–1225. doi: 10.1177/0269881120944161
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Article (Accepted version)
accessLevelRestricted
Identifiers
ISSN of the journal0269-8811
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