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Scientific article
English

Interventions to control MRSA: high time for time-series analysis?

Contributors

Harbarth, Stéphan Juergen; Samore, M. H.

Published in

The journal of antimicrobial chemotherapy, vol. 62, no. 3, p. 431-433

Publication date

2008

Abstract

Time-series methods are useful in quasi-experimental study designs in which rates of antibiotic-resistant infections are ascertained before and after an intervention. However, uncertainties remain regarding the use of time-series analysis as an appropriate research methodology for analysing the effect of infection control interventions and antibiotic policies on the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA). In particular, there is still a substantial gap in our understanding of what actually happens to MRSA incidence when a planned intervention is made on use of one or more antibiotic drug classes.

Keywords

  • Anti-Bacterial Agents/therapeutic use
  • Health Policy
  • Humans
  • Infection Control/methods
  • Methicillin Resistance
  • Staphylococcal Infections/drug therapy/epidemiology/microbiology/prevention & control
  • Staphylococcus aureus/drug effects

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

HARBARTH, Stéphan Juergen, SAMORE, M. H. Interventions to control MRSA: high time for time-series analysis? In: The journal of antimicrobial chemotherapy, 2008, vol. 62, n° 3, p. 431–433. doi: 10.1093/jac/dkn240

Main files (1)

Article (Accepted version)

Identifiers

Additional URL for this publication

http://jac.oxfordjournals.org/cgi/content/full/62/3/431

Journal ISSN

0305-7453
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Technical informations

Creation

25/05/2009 16:46:00

First validation

25/05/2009 16:46:00

Update

14/10/2025 07:12:08

Status update

14/03/2023 15:05:27

Last indexation

10/11/2026 13:10:02
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