Relationship Between Early Functional and Structural Brain Developments and Brain Injury in Preterm Infants

De Wel, O; Van Huffel, S; Lavanga, M; Jansen, K; Dereymaeker, A; Dudink, J; Gui, L; Hüppi, Petra Susan; de Vries, L S; Naulaers, G; Benders, M J N L; Tataranno, M L

doi:10.1007/s12311-021-01232-z

Scientific article

English

Relationship Between Early Functional and Structural Brain Developments and Brain Injury in Preterm Infants

ContributorsDe Wel, O; Van Huffel, S; Lavanga, M; Jansen, K; Dereymaeker, A; Dudink, J; Gui, L; Hüppi, Petra Susan; de Vries, L S; Naulaers, G; Benders, M J N L; Tataranno, M L

Published inCerebellum, vol. 20, no. 4, p. 556-568

Publication date2021

Abstract

Recent studies explored the relationship between early brain function and brain morphology, based on the hypothesis that increased brain activity can positively affect structural brain development and that excitatory neuronal activity stimulates myelination. To investigate the relationship between maturational features from early and serial aEEGs after premature birth and MRI metrics characterizing structural brain development and injury, measured around 30weeks postmenstrual age (PMA) and at term. Moreover, we aimed to verify whether previously developed maturational EEG features are related with PMA.

Keywords

EEG
Neuroimaging
Neuromonitoring
Preterm infants

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research groups

L'imagerie cérébrale (184)

Funding

European Commission - BIOTENSORS (n°339804)
European Commission - MSCA-ITN-2018: :INtegrating Functional Assessment measures for Neonatal Safeguard (INFANS),” under Grant Agreement #813483

Citation (ISO format)

DE WEL, O et al. Relationship Between Early Functional and Structural Brain Developments and Brain Injury in Preterm Infants. In: Cerebellum, 2021, vol. 20, n° 4, p. 556–568. doi: 10.1007/s12311-021-01232-z