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Title

Distinct fMRI patterns colocalized in the cingulate cortex underlie the after-effects of cognitive control on pain

Authors
Chen, Jen-I
Piché, Mathieu
Roy, Mathieu
Vachon-Presseau, Etienne
Woo, Choong-Wan
Wager, Tor D.
Rainville, Pierre
Published in NeuroImage. 2020, vol. 217, 116898
Abstract Demanding tasks can influence following behaviors but the underlying mechanisms remain largely unclear. In the present functional magnetic resonance imaging (fMRI) study, we used multivariate pattern analyses (MVPA) to compare patterns of brain activity associated with pain in response to noxious stimuli administered after a task requiring cognitive control (Stroop) and evaluate their functional interaction based on a mediation analysis model. We found that performing a difficult cognitive task leads to subsequent increases in pain and pain-related multivariate responses across the brain and within the anterior mid-cingulate cortex (aMCC). Moreover, an aMCC pattern predictive of task performance was further reactivated during pain and predicted ensuing increases in pain-related brain responses. This suggests functional interactions between distinct but partly co-localized neural networks underlying executive control and pain. These findings offer a new perspective on the functional role of the cingulate cortex in pain and cognition and provide a promising framework to investigate dynamical interactions between partly overlapping brain networks.
Identifiers
PMID: 32376300
Full text
Structures
Research group Geneva Motivation Lab
Project
Swiss National Science Foundation: PBGEP1-131388
Citation
(ISO format)
SILVESTRINI, Nicolas et al. Distinct fMRI patterns colocalized in the cingulate cortex underlie the after-effects of cognitive control on pain. In: NeuroImage, 2020, vol. 217, p. 116898. doi: 10.1016/j.neuroimage.2020.116898 https://archive-ouverte.unige.ch/unige:155480

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Deposited on : 2021-10-18

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