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Scientific article
Open access
English

Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster randomised trial

Published inBMJ Open, vol. 10, no. 11, e040110
Publication date2020
Abstract

Lopinavir/ritonavir (LPV/r) has been proposed as repurposed drugs for pre-exposure and postexposure prophylaxis as well as therapy of COVID-19. Coronavirus postexposure prophylaxis (COPEP) trial aims at assessing their efficacy as postexposure ring-prophylaxis among adults exposed to SARS-CoV-2.

Keywords
  • Antiviral Agents/therapeutic use
  • Betacoronavirus
  • COVID-19
  • Coronavirus Infections/prevention & control
  • Drug Combinations
  • Humans
  • Lopinavir/therapeutic use
  • Pandemics/prevention & control
  • Pneumonia
  • Viral/prevention & control
  • Post-Exposure Prophylaxis/methods
  • Randomized Controlled Trials as Topic
  • Ritonavir/therapeutic use
  • SARS-CoV-2
  • Switzerland
Citation (ISO format)
SMIT, Mikaëla et al. Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster randomised trial. In: BMJ Open, 2020, vol. 10, n° 11, p. e040110. doi: 10.1136/bmjopen-2020-040110
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Article (Published version)
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Identifiers
ISSN of the journal2044-6055
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