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Improving the quality of Infection Prevention and Control (IPC) evidence: an evaluation of interventions to improve practices and reduce Health Care-Associated Infections (HAIs)

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Defense Thèse de doctorat : Univ. Genève, 2021 - Sc. BioMéd. - S.Glob. 15 - 2021/04/08
Abstract Health care-associated infections are one of the most common adverse events in health care, although a large proportion is preventable using effective infection prevention and control (IPC). Generating high-quality IPC evidence can be challenging given the complex nature of interventions. My thesis employed pragmatic methods to assess IPC interventions and contribute to evidence gaps. Paper one was a systematic review and reanalysis of quasi-experimental studies to assess the impact of IPC on carbapenem-resistant Gram-negative bacilli. Effective intervention components were identified that could be translated into global recommendations. Paper two was a global reliability and usability study which evaluated the WHO IPC assessment framework before its dissemination in health care facilities. Paper three included semi-structured interviews with IPC experts in low-resource countries and a qualitative assessment to identify IPC implementation themes in these settings. A range of themes were categorised according to the WHO IPC core components to inform practical guidance.
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URN: urn:nbn:ch:unige-1525438
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TOMCZYK, Sara Marie. Improving the quality of Infection Prevention and Control (IPC) evidence: an evaluation of interventions to improve practices and reduce Health Care-Associated Infections (HAIs). Université de Genève. Thèse, 2021. doi: 10.13097/archive-ouverte/unige:152543 https://archive-ouverte.unige.ch/unige:152543

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Deposited on : 2021-06-23

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