Doctoral thesis
English

Improving the quality of Infection Prevention and Control (IPC) evidence: an evaluation of interventions to improve practices and reduce Health Care-Associated Infections (HAIs)

Defense date2021-04-08
Abstract

Health care-associated infections are one of the most common adverse events in health care, although a large proportion is preventable using effective infection prevention and control (IPC). Generating high-quality IPC evidence can be challenging given the complex nature of interventions. My thesis employed pragmatic methods to assess IPC interventions and contribute to evidence gaps. Paper one was a systematic review and reanalysis of quasi-experimental studies to assess the impact of IPC on carbapenem-resistant Gram-negative bacilli. Effective intervention components were identified that could be translated into global recommendations. Paper two was a global reliability and usability study which evaluated the WHO IPC assessment framework before its dissemination in health care facilities. Paper three included semi-structured interviews with IPC experts in low-resource countries and a qualitative assessment to identify IPC implementation themes in these settings. A range of themes were categorised according to the WHO IPC core components to inform practical guidance.

Citation (ISO format)
TOMCZYK, Sara Marie. Improving the quality of Infection Prevention and Control (IPC) evidence: an evaluation of interventions to improve practices and reduce Health Care-Associated Infections (HAIs). Doctoral Thesis, 2021. doi: 10.13097/archive-ouverte/unige:152543
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Creation20/06/2021 17:02:00
First validation20/06/2021 17:02:00
Update time04/04/2025 13:07:55
Status update21/03/2024 10:08:12
Last indexation13/05/2025 18:40:55
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