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Title

Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients
Authors
Ageron, Francois-Xavier
Gayet-Ageron, Angèle
Ker, Katharine
Coats, Timothy J
Shakur-Still, Haleema
Roberts, Ian
Collaboration
Published in British Journal of Anaesthesia. 2020, vol. 124, no. 6, p. 676-683
Abstract Early administration of the antifibrinolytic drug tranexamic acid reduces death from bleeding in trauma and postpartum haemorrhage. We examined how the effectiveness and safety of antifibrinolytic drugs varies by the baseline risk of death as a result of bleeding.
Keywords Acute Disease — Adult — Antifibrinolytic Agents/therapeutic use — Female — Hemorrhage/drug therapy — Humans — Male — Randomized Controlled Trials as Topic — Risk — Tranexamic Acid/therapeutic use — Young Adult
Identifiers
PMID: 32199584
Full text
Article (Published version) (532 Kb) - public document Free access
Appendix (572 Kb) - public document Free access
Other version: https://www.sciencedirect.com/science/article/pii/S0007091220300830
Structures
Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires
Faculté de médecine / Centre de recherche clinique
Research group Epidémiologie clinique et biostatistique (115)
Citation
(ISO format) 		AGERON, Francois-Xavier et al. Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients. In: British Journal of Anaesthesia, 2020, vol. 124, n° 6, p. 676-683. doi: 10.1016/j.bja.2020.01.020 https://archive-ouverte.unige.ch/unige:151584

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Deposited on : 2021-05-11

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