Does perfusion computed tomography facilitate clinical decision making for thrombolysis in unselected acute patients with suspected ischaemic stroke?

Agarwal, S; Jones, P S; Alawneh, J A; Antoun, N M; Barry, P J; Carrera, Emmanuel; Cotter, P E; O'Brien, E W; Salih, I; Scoffings, D J; Baron, J-C; Warburton, E A

doi:10.1159/000329310

Scientific article

English

Does perfusion computed tomography facilitate clinical decision making for thrombolysis in unselected acute patients with suspected ischaemic stroke?

ContributorsAgarwal, S; Jones, P S; Alawneh, J A; Antoun, N M; Barry, P J; Carrera, Emmanuel; Cotter, P E; O'Brien, E W; Salih, I; Scoffings, D J; Baron, J-C; Warburton, E A

Published inCerebrovascular Diseases, vol. 32, no. 3, p. 227-233

Publication date2011

Abstract

Despite use in clinical practice and major positive trials of thrombolysis, non-contrast computed tomography (NCCT) is not sensitive for identifying penumbral tissue in acute stroke. This study evaluated how physiological imaging using CT perfusion (CTP) could add to the diagnostic utility of an NCCT and inform clinical decisions regarding thrombolysis.

Keywords

Adult
Aged
Aged, 80 and over
Blood Flow Velocity/drug effects
Brain Ischemia/diagnostic imaging/drug therapy/physiopathology
Cerebral Angiography
Cerebrovascular Circulation/drug effects
Chi-Square Distribution
Decision Support Techniques
England
Female
Humans
Male
Middle Aged
Observer Variation
Patient Selection
Perfusion Imaging/methods
Predictive Value of Tests
Regional Blood Flow/drug effects
Reproducibility of Results
Retrospective Studies
Stroke/diagnostic imaging/drug therapy/physiopathology
Thrombolytic Therapy
Tomography, X-Ray Computed

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

AGARWAL, S et al. Does perfusion computed tomography facilitate clinical decision making for thrombolysis in unselected acute patients with suspected ischaemic stroke? In: Cerebrovascular Diseases, 2011, vol. 32, n° 3, p. 227–233. doi: 10.1159/000329310

Article (Published version)

Identifiers

PID : unige:151445
DOI : 10.1159/000329310
PMID : 21860235

Journal ISSN1015-9770

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Does perfusion computed tomography facilitate clinical decision making for thrombolysis in unselected acute patients with suspected ischaemic stroke?

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