Living donor nephrectomy represents a challenging surgery. It must maximize safety and decrease morbidity for the healthy donor. With these goals living donation gradually shifted over the last decade from open to minimally invasive surgery. Compared to open surgery, laparoscopy added less post-operative pain, short hospital stay, lower incisional morbidity, quicker recovery and improved cosmesis, increasing the patient acceptance However, the relatively slow and incomplete technical shift observed is most probably related to the complexity of minimally invasive surgery making it a challenge for medium to low volume centers. In this context, the aim of our research is to analyse the progressive shift from open to minimally-invasive living DN in a center performing this procedure on a monthly basis. For this purpose we conducted an observational retrospective analysis of 169 consecutive living donor Results of our study shows that the evolution from open to minimally invasive DN can be achieved even in a low-volume center with an acceptable surgical safety and efficiency profile. Indeed, the results of RLDN and RLN were comparable to those of larger centers