UNIGE document Scientific Article
previous document  unige:144118  next document
add to browser collection
Title

Hyperthyroidism and bone mineral density: Dissecting the causal association with Mendelian randomization analysis

Authors
Deshmukh, Harshal
Aye, Mo
England, James
Abdalla, Mohammed
Sathyapalan, Thozhukat
Published in Clinical Endocrinology. 2020
Abstract Introduction: Untreated hyperthyroidism is associated with accelerated bone turnover, low bone mineral density (BMD) and increased susceptibility to fragility fractures. Although treatment appears to improve or even reverse some of these adverse skeletal effects, there is limited guidance on routine BMD assessment in hyperthyroid patients following treatment. By using Mendelian randomization (MR) analysis, we aimed to assess the causal association of hyperthyroid thyroid states with BMD and fractures using the UK Biobank.
Keywords BoneBone densityFracturesGraves diseaseHyperthyroidismInvestigationsThyroid
Identifiers
PMID: 32947644
Full text
Structures
Research group Génétique des ostéoporoses (544)
Citation
(ISO format)
DESHMUKH, Harshal et al. Hyperthyroidism and bone mineral density: Dissecting the causal association with Mendelian randomization analysis. In: Clinical Endocrinology, 2020. doi: 10.1111/cen.14330 https://archive-ouverte.unige.ch/unige:144118

32 hits

0 download

Update

Deposited on : 2020-11-04

Export document
Format :
Citation style :