UNIGE document Scientific Article - Letter
previous document  unige:143187  next document
add to browser collection
Title

Diffusion magnetic resonance imaging detects an increase in interstitial fibrosis earlier than the decline of renal function

Authors show hidden authors show all authors [1 - 9]
Published in Nephrology Dialysis Transplantation. 2020, vol. 35, no. 7, p. 1274-1276
Abstract 19 kidney allografts patients had repeated biopsies for clinical purposes and parallel MRI examinations. There was no significant correlation between eGFR and renal interstitial fibrosis (IF) at baseline, whereas baseline deltaADC (a MRI derived parameter sensitive to the water diffusion in the tissue) correlated. negatively to renal interstitial fibrosis (IF). Considering the difference between the basal and follow-up values, there was a good correlation between the evolution of IF and deltaADC but not between the evolution of IF and eGFR. These results suggest that deltaADC may be more reliable than eGFR to allow earlier detection of an increase in IF.
Keywords Magnetic resonanceDiffusionChronic kidney disease
Identifiers
PMID: 32160279
Full text
Structures
Research groups Analyse protéomique et Analyse génomique des maladies rénales (659)
Groupe Pierre-Yves Martin (néphrologie) (30)
Imagerie cardiaque fonctionnelle (541)
Insuffisance rénale chronique (941)
Projects
Swiss National Science Foundation: IZCOZ0_177140
Swiss National Science Foundation: 320038_159714; IZCOZ0_177140; PP00P3_127454
Swiss National Science Foundation: PRISMAMRI (R'Equip grants 326030_150816)
Citation
(ISO format)
BERCHTOLD, Lena et al. Diffusion magnetic resonance imaging detects an increase in interstitial fibrosis earlier than the decline of renal function. In: Nephrology Dialysis Transplantation, 2020, vol. 35, n° 7, p. 1274-1276. doi: 10.1093/ndt/gfaa007 https://archive-ouverte.unige.ch/unige:143187

249 hits

17 downloads

Update

Deposited on : 2020-10-15

Export document
Format :
Citation style :