Estimation of Population Admixture from Paleogenomic Data using Spatially Explicit Simulations

Rio, Jérémy Marc Xavier

doi:10.13097/archive-ouverte/unige:140130

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Title		Estimation of Population Admixture from Paleogenomic Data using Spatially Explicit Simulations
Author		Rio, Jérémy Marc Xavier
Director		Currat, Mathias
Defense		Thèse de doctorat : Univ. Genève, 2020 - Sc. Vie 53 - 2020/02/26
Abstract		Genomes are full of informations related to our evolutionary history. In this thesis I'm interested in making inferences on past human population interactions by simulating paleogenomic data under different historical contexts. The originality of this approach lies on the simulation of paleogenomes in a spatially explicit simulation framework that integrates demograhy, migration and admixture of populations. Chapter 2 and 3 are related to the test of population continuity, in two different contexts. Chapter 4 and 5 are exploratory analyses in which (i) I explore the effect of spatio-temporally heterogeneous environments on the population continuity test and (ii) I explore different methods to identify a subset of paleogenomes from a database base filling the requirements of our spatially explicit approach. In Chapter 6, I extend the simulation approach to study populations of the Bronze Age in Central Europe under different demographic scenarios.
Keywords		Admixture — Paleogenome — Spatially explicit simulations — Bronze Age — Neolithic — Paleolithic — Demography — Environment — Spatio-temporally variable — Fst — Heterozygosity — Long distance dispersal — Competition — Deme — Genomic contribution — Genomic component
Identifiers		DOI: 10.13097/archive-ouverte/unige:140130 URN: urn:nbn:ch:unige-1401303
Full text		Thesis (14.9 MB) - Limited access to UNIGE (until 2024-06-30)
Structures		Faculté des sciences / Section de biologie / Département de génétique et évolution
Research group		Unité d'anthropologie
Projects		Swiss National Science Foundation: 31003A_156853 Swiss National Science Foundation: 31003A_182577
Citation (ISO format)		RIO, Jérémy Marc Xavier. Estimation of Population Admixture from Paleogenomic Data using Spatially Explicit Simulations. Université de Genève. Thèse, 2020. doi: 10.13097/archive-ouverte/unige:140130 https://archive-ouverte.unige.ch/unige:140130