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Doctoral thesis
English

Estimation of Population Admixture from Paleogenomic Data using Spatially Explicit Simulations

Defense date2020-02-26
Abstract

Genomes are full of informations related to our evolutionary history. In this thesis I'm interested in making inferences on past human population interactions by simulating paleogenomic data under different historical contexts. The originality of this approach lies on the simulation of paleogenomes in a spatially explicit simulation framework that integrates demograhy, migration and admixture of populations. Chapter 2 and 3 are related to the test of population continuity, in two different contexts. Chapter 4 and 5 are exploratory analyses in which (i) I explore the effect of spatio-temporally heterogeneous environments on the population continuity test and (ii) I explore different methods to identify a subset of paleogenomes from a database base filling the requirements of our spatially explicit approach. In Chapter 6, I extend the simulation approach to study populations of the Bronze Age in Central Europe under different demographic scenarios.

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Keywords
  • Admixture
  • Paleogenome
  • Spatially explicit simulations
  • Bronze Age
  • Neolithic
  • Paleolithic
  • Demography
  • Environment
  • Spatio-temporally variable
  • Fst
  • Heterozygosity
  • Long distance dispersal
  • Competition
  • Deme
  • Genomic contribution
  • Genomic component
Citation (ISO format)
RIO, Jérémy Marc Xavier. Estimation of Population Admixture from Paleogenomic Data using Spatially Explicit Simulations. 2020. doi: 10.13097/archive-ouverte/unige:140130
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Thesis
accessLevelRestrictedaccessLevelPublic 06/30/2024
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Technical informations

Creation06/30/2020 5:09:00 PM
First validation06/30/2020 5:09:00 PM
Update time03/15/2023 10:27:33 PM
Status update03/15/2023 10:27:32 PM
Last indexation01/29/2024 10:17:48 PM
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