Incorporation of GSTA1 genetic variations into a population pharmacokinetic model for IV busulfan in paediatric hematopoietic stem cell transplantation
Published inBritish Journal of Clinical Pharmacology, vol. 84, no. 7, p. 1494-1504
Publication date2018
Abstract
Keywords
- Administration
- Intravenous
- Area Under Curve
- Busulfan/administration & dosage/pharmacokinetics
- Child
- Preschool
- Feasibility Studies
- Female
- Glutathione Transferase/genetics/metabolism
- Graft Rejection/immunology/prevention & control
- Hematopoietic Stem Cell Transplantation/adverse effects
- Humans
- Immunosuppressive Agents/administration & dosage/pharmacokinetics
- Infant
- Male
- Models
- Biological
- Polymorphism
- Single Nucleotide
- Precision Medicine/methods
- Transplantation Conditioning/methods
- GSTA1
- Busulfan
- Children
- Polymorphisms
- Population pharmacokinetics
- Stem cell transplantation
Research group
Citation (ISO format)
NAVA, Tiago et al. Incorporation of GSTA1 genetic variations into a population pharmacokinetic model for IV busulfan in paediatric hematopoietic stem cell transplantation. In: British Journal of Clinical Pharmacology, 2018, vol. 84, n° 7, p. 1494–1504. doi: 10.1111/bcp.13566
Main files (1)
Article (Published version)
Identifiers
- PID : unige:128688
- DOI : 10.1111/bcp.13566
- PMID : 29469189
ISSN of the journal0306-5251