Scientific article
Review
OA Policy
English

Antifibrinolytic drugs for treating primary postpartum haemorrhage

Published inThe Cochrane database of systematic reviews, vol. 2, CD012964
Publication date2018
Abstract

Postpartum haemorrhage (PPH) - heaving bleeding within the first 24 hours after giving birth - is one of the main causes of death of women after childbirth. Antifibrinolytics, primarily tranexamic acid (TXA), have been shown to reduce bleeding in surgery and safely reduces mortality in trauma patients with bleeding without increasing the risk of adverse events.An earlier Cochrane review on treatments for primary PPH covered all the various available treatments - that review has now been split by types of treatment. This new review concentrates only on the use of antifibrinolytic drugs for treating primary PPH.

Keywords
  • Antifibrinolytic Agents/administration & dosage/therapeutic use
  • Cause of Death
  • Female
  • Humans
  • Maternal Mortality
  • Misoprostol/administration & dosage/therapeutic use
  • Postpartum Hemorrhage/drug therapy/mortality
  • Pregnancy
  • Randomized Controlled Trials as Topic
  • Tranexamic Acid/administration & dosage/therapeutic use
Citation (ISO format)
SHAKUR, Haleema et al. Antifibrinolytic drugs for treating primary postpartum haemorrhage. In: The Cochrane database of systematic reviews, 2018, vol. 2, p. CD012964. doi: 10.1002/14651858.CD012964
Main files (1)
Article (Published version)
Identifiers
Additional URL for this publicationhttps://www.ncbi.nlm.nih.gov/pubmed/29462500
Journal ISSN1361-6137
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Technical informations

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First validation11/10/2019 12:10:00
Update time15/03/2023 18:35:30
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