3′-Deoxy-3′-Hydroxyamino-β-D-Xylofuranosyluracil and Derivatives Thereof

Tronchet, Jean Marcel Julien; Benhamza, Rachid; Dolatshahi-Missaghie, Naz; Geoffroy, Michel; Turler, Hans

doi:10.1080/07328318808070208

Scientific article

English

3′-Deoxy-3′-Hydroxyamino-β-D-Xylofuranosyluracil and Derivatives Thereof

ContributorsTronchet, Jean Marcel Julien; Benhamza, Rachid; Dolatshahi-Missaghie, Naz; Geoffroy, Michel; Turler, Hans

Published inNucleosides & Nucleotides, vol. 7, no. 2, p. 249-269

Publication date1988

Abstract

The title compound was prepared by reduction of the oxime of the 3′-ketouridine. Condensation with aldehydes gave a series of nitrones whose reduction afforded “second generation” hydroxylamines, some of which showing antiviral activity. The nitroxide free radicals formed upon oxidation of hydroxylamines gave good ESR spectra useful for configurational and conformational assignments.

Affiliation entities

Citation (ISO format)

TRONCHET, Jean Marcel Julien et al. 3′-Deoxy-3′-Hydroxyamino-β-D-Xylofuranosyluracil and Derivatives Thereof. In: Nucleosides & Nucleotides, 1988, vol. 7, n° 2, p. 249–269. doi: 10.1080/07328318808070208

Article (Published version)

Identifiers

PID : unige:127567
DOI : 10.1080/07328318808070208

Commercial URLhttp://www.tandfonline.com/doi/abs/10.1080/07328318808070208

ISSN of the journal0732-8311

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3′-Deoxy-3′-Hydroxyamino-β-D-Xylofuranosyluracil and Derivatives Thereof

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