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Title

Pretherapeutic resting-state fMRI profiles are associated with MR signature volumes after stereotactic radiosurgical thalamotomy for essential tremor

Authors
Tuleasca, Constantin
Régis, Jean
Najdenovska, Elena
Witjas, Tatiana
Girard, Nadine
Bolton, Thomas
Delaire, Francois
Vincent, Marion
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Published in Journal of Neurosurgery. 2018, vol. 129, no. Suppl 1, p. 63-71
Abstract Essential tremor (ET) is the most common movement disorder. Drug-resistant ET can benefit from standard stereotactic deep brain stimulation or radiofrequency thalamotomy or, alternatively, minimally invasive techniques, including stereotactic radiosurgery (SRS) and high-intensity focused ultrasound, at the level of the ventral intermediate nucleus (Vim). The aim of the present study was to evaluate potential correlations between pretherapeutic interconnectivity (IC), as depicted on resting-state functional MRI (rs-fMRI), and MR signature volume at 1 year after Vim SRS for tremor, to be able to potentially identify hypo- and hyperresponders based only on pretherapeutic neuroimaging data.
Keywords Stereotactic radiosurgeryGamma KnifeThalamotomyVimResting-state fMRI
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PMID: 30544321
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Research group Traitement d'images médicales (893)
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TULEASCA, Constantin et al. Pretherapeutic resting-state fMRI profiles are associated with MR signature volumes after stereotactic radiosurgical thalamotomy for essential tremor. In: Journal of Neurosurgery, 2018, vol. 129, n° Suppl 1, p. 63-71. doi: 10.3171/2018.7.GKS18752 https://archive-ouverte.unige.ch/unige:126143

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Deposited on : 2019-11-13

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