Scientific article
English

The CST3 B haplotype is associated with frontotemporal lobar degeneration

Published inEuropean Journal of Neurology, vol. 17, no. 1, p. 143-146
Publication date2010
Abstract

Frontotemporal lobar degeneration (FTLD) is a common cause of early-onset dementia. Given the role of cystatin C in brain neurodegeneration and neuroregeneration, the aim of this study was to determine whether the cystatin C gene (CST3) was genetically associated with FTLD.

Keywords
  • Aged
  • Brain/metabolism/pathology/physiopathology
  • Cystatin C/genetics
  • DNA Mutational Analysis
  • Female
  • Frontotemporal Lobar Degeneration/genetics/metabolism/physiopathology
  • Genetic Markers/genetics
  • Genetic Predisposition to Disease/genetics
  • Genetic Testing
  • Haplotypes/genetics
  • Humans
  • Intercellular Signaling Peptides and Proteins/genetics
  • Male
  • Middle Aged
  • Progranulins
  • Risk Factors
Affiliation entities Not a UNIGE publication
Citation (ISO format)
BENUSSI, L et al. The CST3 B haplotype is associated with frontotemporal lobar degeneration. In: European Journal of Neurology, 2010, vol. 17, n° 1, p. 143–146. doi: 10.1111/j.1468-1331.2009.02767.x
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
Journal ISSN1351-5101
279views
0downloads

Technical informations

Creation04/01/2019 17:30:00
First validation04/01/2019 17:30:00
Update15/03/2023 15:43:24
Status update15/03/2023 15:43:23
Last indexation31/10/2024 12:39:21
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack