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Title

The CST3 B haplotype is associated with frontotemporal lobar degeneration

Authors
Benussi, L
Ghidoni, R
Galimberti, D
Fenoglio, C
Scarpini, E
Binetti, G
Published in European Journal of Neurology. 2010, vol. 17, no. 1, p. 143-146
Abstract Frontotemporal lobar degeneration (FTLD) is a common cause of early-onset dementia. Given the role of cystatin C in brain neurodegeneration and neuroregeneration, the aim of this study was to determine whether the cystatin C gene (CST3) was genetically associated with FTLD.
Keywords AgedBrain/metabolism/pathology/physiopathologyCystatin C/geneticsDNA Mutational AnalysisFemaleFrontotemporal Lobar Degeneration/genetics/metabolism/physiopathologyGenetic Markers/geneticsGenetic Predisposition to Disease/geneticsGenetic TestingHaplotypes/geneticsHumansIntercellular Signaling Peptides and Proteins/geneticsMaleMiddle AgedProgranulinsRisk Factors
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PMID: 19674067
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BENUSSI, L et al. The CST3 B haplotype is associated with frontotemporal lobar degeneration. In: European Journal of Neurology, 2010, vol. 17, n° 1, p. 143-146. https://archive-ouverte.unige.ch/unige:114066

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Deposited on : 2019-02-08

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