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Other version: http://www.springerlink.com/content/82cvdgej85gf6d1w/fulltext.pdf
Forging the endothelium during inflammation: pushing at a half-open door?
|Published in||Cell and Tissue Research. 2003, vol. 314, no. 1, p. 93-105|
Open Access - Licence nationale Springer
|Abstract||During an inflammatory response, changes in the adhesive properties of the endothelium occur that enable normally non-adherent blood-borne leukocytes to adhere and subsequently to traverse the endothelium through small gaps at inter-cellular junctions. This review concentrates on the role played by inter-endothelial adhesion molecules during transmigration and the way in which their expression may be regulated during inflammation. We show that the final "open" signals that lead to the formation of clefts between adjacent endothelial cells may be derived from inflamed tissue underlying the endothelium and from activated leukocytes.|
|Keywords||Animals — Capillary Permeability — Cell Adhesion — Cell Adhesion Molecules/ physiology — Cell Communication — Cell Movement — Endothelium, Vascular/cytology/ physiology — Humans — Inflammation — Intercellular Junctions/ physiology — Leukocytes/physiology — Signal Transduction|
|JOHNSON-LEGER, Caroline, IMHOF, Beat. Forging the endothelium during inflammation: pushing at a half-open door?. In: Cell and Tissue Research, 2003, vol. 314, n° 1, p. 93-105. doi: 10.1007/s00441-003-0775-4 https://archive-ouverte.unige.ch/unige:11365|