Scientific article

A score identifying serious bacterial infections in children with fever without source

Published inThe Pediatric infectious disease journal, vol. 27, no. 7, p. 654-656
Publication date2008

The objective of the study was to develop a simple clinical tool to identify serious bacterial infection (SBI) in children with fever without a source. For each child, a clinical assessment, a white blood cell count, a urine analysis, a determination of C-reactive protein, procalcitonin, and appropriate cultures were performed. Two hundred two children were studied of whom 54 (27%) had SBI. In the multivariate analysis, only procalcitonin [odds ratio (OR): 37.6], C-reactive protein (OR: 7.8), and urine dipstick (OR: 23.2) remained significantly associated with SBI. The sensitivity of the score for the identification of SBI was 94% and the specificity 81%. In the validation set the sensitivity of the score was 94% and the specificity 78%.

  • Bacteria/isolation & purification
  • Bacterial Infections/diagnosis/pathology/physiopathology
  • C-Reactive Protein/analysis
  • Calcitonin/blood
  • Child, Preschool
  • Fever of Unknown Origin/etiology
  • Humans
  • Infant
  • Infant, Newborn
  • Leukocyte Count
  • Protein Precursors/blood
  • Sensitivity and Specificity
  • Urinalysis
Citation (ISO format)
GALETTO-LACOUR, Annick, ZAMORA, Samuel Antonio, GERVAIX, Alain. A score identifying serious bacterial infections in children with fever without source. In: The Pediatric infectious disease journal, 2008, vol. 27, n° 7, p. 654–656. doi: 10.1097/INF.0b013e318168d2b4
Main files (1)
Article (Accepted version)
ISSN of the journal0891-3668

Technical informations

Creation03/12/2009 2:12:00 PM
First validation03/12/2009 2:12:00 PM
Update time03/14/2023 3:03:17 PM
Status update03/14/2023 3:03:17 PM
Last indexation10/18/2023 10:17:04 AM
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