Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function

Quercioli, Alessandra; Carbone, Federico; Bonaventura, Aldo; Liberale, Luca; Pataky, Zoltan; Thomas, Aurélien; Lenglet, Sébastien; Lauer, Estelle; Golay, Alain; Dallegri, Franco; Di Marzo, Vincenzo; Schindler, Thomas H; Montecucco, Fabrizio

doi:10.1016/j.ijcard.2016.12.023

Scientific article

English

Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function

ContributorsQuercioli, Alessandra; Carbone, Federico; Bonaventura, Aldo; Liberale, Luca; Pataky, Zoltan

; Thomas, Aurélien; Lenglet, Sébastien; Lauer, Estelle; Golay, Alain; Dallegri, Franco; Di Marzo, Vincenzo; Schindler, Thomas H; Montecucco, Fabrizio

Published inInternational Journal of Cardiology, vol. 231, p. 1-5

Publication date2017

Abstract

Among endocannabinoid (EC)-related mediators, Oleoyl-ethanolamide (OEA) and Palmitoyl-ethanolamide (PEA), two endogenous PPARα agonists with lipolytic and anti-inflammatory action, respectively, are being actively investigated. Here, we assessed the potential association between plasma levels of PEA and OEA and coronary function in a cohort including normal, overweight, obese, and morbidly obese (MOB) individuals.

Keywords

Biomarkers/blood
Body Mass Index
Chromatography, Liquid
Coronary Artery Disease/blood/diagnosis/etiology
Coronary Circulation/physiology
Coronary Vessels/diagnostic imaging/physiopathology
Electrocardiography
Enzyme-Linked Immunosorbent Assay
Ethanolamines/blood
Humans
Obesity/blood/complications
Palmitic Acids/blood
Positron Emission Tomography Computed Tomography
Regional Blood Flow/physiology
Vasoconstriction/physiology

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de médecine légale

Research groups

Citation (ISO format)

QUERCIOLI, Alessandra et al. Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function. In: International Journal of Cardiology, 2017, vol. 231, p. 1–5. doi: 10.1016/j.ijcard.2016.12.023

Article (Published version)

Identifiers

PID : unige:112122
DOI : 10.1016/j.ijcard.2016.12.023
PMID : 27989579

Journal ISSN0167-5273

538views

0downloads

Creation19/09/2018 09:41:00

First validation19/09/2018 09:41:00

Update15/03/2023 15:12:50

Status update15/03/2023 15:12:50

Last indexation31/10/2024 12:10:49

Archive ouverte UNIGE

Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function

Technical informations