UNIGE document Scientific Article
previous document  unige:104791  next document
add to browser collection

Time domain diffuse Raman spectrometer based on a TCSPC camera for the depth analysis of diffusive media

Konugolu Venkata Sekar, S
Mosca, S
Tannert, S
Valentini, G
Martelli, F
Prokazov, Y
Turbin, E
show hidden authors show all authors [1 - 11]
Published in Optics letters. 2018, vol. 43, no. 9, p. 2134-2137
Abstract We present a time domain diffuse Raman spectrometer for depth probing of highly scattering media. The system is based on, to the best of our knowledge, a novel time-correlated single-photon counting (TCSPC) camera that simultaneously acquires both spectral and temporal information of Raman photons. A dedicated non-contact probe was built, and time domain Raman measurements were performed on a tissue mimicking bilayer phantom. The fluorescence contamination of the Raman signal was eliminated by early time gating (0-212 ps) the Raman photons. Depth sensitivity is achieved by time gating Raman photons at different delays with a gate width of 106 ps. Importantly, the time domain can provide time-dependent depth sensitivity leading to a high contrast between two layers of Raman signal. As a result, an enhancement factor of 2170 was found for our bilayer phantom which is much higher than the values obtained by spatial offset Raman spectroscopy (SORS), frequency offset Raman spectroscopy (FORS), or hybrid FORS-SORS on a similar phantom.
PMID: 29714764
Full text
Article (Published version) (1.8 MB) - document accessible for UNIGE members only Limited access to UNIGE
Research group Groupe Binzoni Tiziano (radiologie) (234)
(ISO format)
KONUGOLU VENKATA SEKAR, S et al. Time domain diffuse Raman spectrometer based on a TCSPC camera for the depth analysis of diffusive media. In: Optics Letters, 2018, vol. 43, n° 9, p. 2134-2137. https://archive-ouverte.unige.ch/unige:104791

319 hits

0 download


Deposited on : 2018-05-31

Export document
Format :
Citation style :