Photoreceptor-mediated regulation of the COP1/SPA E3 ubiquitin ligase

Podolec, Roman; Ulm, Roman

doi:10.1016/j.pbi.2018.04.018

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Title		Photoreceptor-mediated regulation of the COP1/SPA E3 ubiquitin ligase
Authors		Podolec, Roman Ulm, Roman
Published in		Current opinion in plant biology. 2018, vol. 45, p. 18-25
Abstract		Plants have evolved specific photoreceptors that capture informational cues from sunlight. The phytochrome, cryptochrome, and UVR8 photoreceptors perceive red/far-red, blue/UV-A, and UV-B light, respectively, and control overlapping photomorphogenic responses important for plant growth and development. A major repressor of such photomorphogenic responses is the E3 ubiquitin ligase formed by CONSTITUTIVELY PHOTOMORPHOGENIC 1 (COP1) and SUPPRESSOR OF PHYA-105 (SPA) proteins, which acts by regulating the stability of photomorphogenesis-promoting transcription factors. The direct interaction of light-activated photoreceptors with the COP1/SPA complex represses its activity via nuclear exclusion of COP1, disruption of the COP1-SPA interaction, and/or SPA protein degradation. This process enables plants to integrate different light signals at the level of the COP1/SPA complex to enact appropriate photomorphogenic responses according to the light environment.
Identifiers		DOI: 10.1016/j.pbi.2018.04.018 PMID: 29775763
Full text		Article (Published version) (620 Kb) - Free access Other version: https://www.sciencedirect.com/science/article/pii/S136952661730208X
Structures		Faculté des sciences / Section de biologie / Département de botanique et biologie végétale Centres et instituts / Institut de génétique et de génomique
Research group		Groupe Ulm
Citation (ISO format)		PODOLEC, Roman, ULM, Roman. Photoreceptor-mediated regulation of the COP1/SPA E3 ubiquitin ligase. In: Current Opinion in Plant Biology, 2018, vol. 45, p. 18-25. doi: 10.1016/j.pbi.2018.04.018 https://archive-ouverte.unige.ch/unige:104620