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Title

Cyclooxygenase-2-Derived Prostaglandins Mediate Cerebral Microcirculation in a Juvenile Ischemic Rat Model
Authors
Leger, Pierre-Louis
Pansiot, Julien
Besson, Valerie
Palmier, Bruno
Renolleau, Sylvain
Baud, Olivier
Cauli, Bruno
Charriaut-Marlangue, Christiane
Published in Stroke. 2016, vol. 47, no. 12, p. 3048-3052
Abstract We previously showed that the selective neuronal nitric oxide synthase inhibitor 7-nitroindazole (7-NI) increases cerebral microcirculation in a juvenile ischemic rat model. We address the roles of cyclooxygenase (COX)-elaborated prostaglandins in collateral recruitment and blood supply.
Keywords 6-Ketoprostaglandin F1 alpha/metabolism — Animals — Cerebrovascular Circulation — Cyclooxygenase 2/metabolism — Cyclooxygenase 2 Inhibitors/pharmacology — Disease Models, Animal — Microcirculation — Prostaglandin-E Synthases/metabolism — Rats — Reperfusion Injury/metabolism
Identifiers
PMID: 27834752
Full text
Article (Published version) (10.1 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research group Prévention des complications néonatales d'origine périnatale (990)
Citation
(ISO format) 		LEGER, Pierre-Louis et al. Cyclooxygenase-2-Derived Prostaglandins Mediate Cerebral Microcirculation in a Juvenile Ischemic Rat Model. In: Stroke, 2016, vol. 47, n° 12, p. 3048-3052. doi: 10.1161/STROKEAHA.116.015095 https://archive-ouverte.unige.ch/unige:104564

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Deposited on : 2018-05-18

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