Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis

Neu, Scott C; Pa, Judy; Kukull, Walter; Beekly, Duane; Kuzma, Amanda; Gangadharan, Prabhakaran; Wang, Li-San; Romero, Klaus; Arneric, Stephen P; Redolfi, Alberto; Orlandi, Daniele; Frisoni, Giovanni; Au, Rhoda; Devine, Sherral; Auerbach, Sanford; Espinosa, Ana; Boada, Mercè; Ruiz, Agustín; Johnson, Sterling C; Koscik, Rebecca; Wang, Jiun-Jie; Hsu, Wen-Chuin; Chen, Yao-Liang; Toga, Arthur W

doi:10.1001/jamaneurol.2017.2188

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Title		Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis
Authors		Neu, Scott C Pa, Judy Kukull, Walter Beekly, Duane Kuzma, Amanda Gangadharan, Prabhakaran Wang, Li-San Romero, Klaus Arneric, Stephen P Redolfi, Alberto Orlandi, Daniele Frisoni, Giovanni Au, Rhoda Devine, Sherral Auerbach, Sanford Espinosa, Ana Boada, Mercè Ruiz, Agustín Johnson, Sterling C Koscik, Rebecca Wang, Jiun-Jie Hsu, Wen-Chuin Chen, Yao-Liang Toga, Arthur W show all authors [1 - 24]
Published in		JAMA Neurology. 2017, vol. 74, no. 10, p. 1178-1189
Abstract		It is unclear whether female carriers of the apolipoprotein E (APOE) ε4 allele are at greater risk of developing Alzheimer disease (AD) than men, and the sex-dependent association of mild cognitive impairment (MCI) and APOE has not been established.
Keywords		Aged — 80 and over — Alzheimer Disease/epidemiology/genetics — Apolipoproteins E/genetics — Case-Control Studies — Databases — Factual/statistics & numerical data — Female — Humans — Logistic Models — Male — Middle Aged — Risk Factors — Sex Characteristics
Identifiers		DOI: 10.1001/jamaneurol.2017.2188 PMID: 28846757
Full text		Article (Accepted version) (398 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de psychiatrie
Research group		Troubles de mémoire et maladie d'Alzeimer (935)
Citation (ISO format)		NEU, Scott C et al. Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis. In: JAMA Neurology, 2017, vol. 74, n° 10, p. 1178-1189. doi: 10.1001/jamaneurol.2017.2188 https://archive-ouverte.unige.ch/unige:100624