UNIGE document Scientific Article
previous document  unige:10044  next document
add to browser collection
Title

Les "synapses neurosécrétoires", hier et aujourd'hui

Authors
Dreifuss, Jean-Jacques
Published in Annales d'endocrinologie. 1985, vol. 46, no. 1, p. 47-53
Abstract The concept of peptidergic neurotransmission in the central nervous system ranks high in contemporary neurobiology. It was first formulated by J. Barry when reporting, in 1954-55, his observation with light microscopy of the existence of "Gomori-positive" synapses in sections of the mammalian brain. However, this important discovery had virtually no impact on the scientific community for about twenty years because of an extremely restrictive definition of "neurosecretion" during this period by the practitioners of the new field known as neuroendocrinology. The rejection of Barry's finding raises numerous epistemological questions; it provides another example of a "premature discovery", such as those of A.A. Berthold (testicular transplant studies) and of J.G. Mendel (artificial plant hybridization) during the last century.
Keywords AnimalsCalcium/metabolismHippocampus/physiologyHypothalamus/physiologyMicroscopy, ElectronModels, BiologicalNeurosecretionNeurosecretory Systems/ cytologyOxytocin/pharmacologyPotassium/pharmacologyRatsReceptors, Angiotensin/metabolismReceptors, OxytocinSnakesSynapses/ physiologyVasopressins/metabolismVeratridine/pharmacology
Identifiers
PMID: 3002229
Full text
This document has no fulltext available yet, but you can contact its author by using the form below.
Structures
Citation
(ISO format)
DREIFUSS, Jean-Jacques, RAGGENBASS, Mario. Les "synapses neurosécrétoires", hier et aujourd'hui. In: Annales d'endocrinologie, 1985, vol. 46, n° 1, p. 47-53. https://archive-ouverte.unige.ch/unige:10044

119 hits

0 download

Update

Deposited on : 2010-08-06

Export document
Format :
Citation style :