Section des sciences pharmaceutiques

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2022

Scientific Articles

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A New Practice to Monitor the Fabrication Process of Fab-Targeting Ligands from Bevacizumab by LC-MS: Preparation and Analytical CharacterizationMarquet, Franck; D'Atri, Valentina; Guillarme, Davy; Borchard, Gerrit;
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A simple mathematical treatment for predicting linear solvent strength behavior in gradient elution: Application to biomoleculesGuillarme, Davy; Bouvarel, Thomas; Rouvière, Florent; Heinisch, Sabine;
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An integrated metabolomics and proteogenomics approach reveals molecular alterations following carbamazepine exposure in the male mussel Mytilus galloprovincialisDumas, Thibaut; Courant, Frédérique; Almunia, Christine; Boccard, Julien; ... Gomez, Elena
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Analytical Similarity Assessment of Biosimilars: Global Regulatory Landscape, Recent Studies and Major Advancements in Orthogonal PlatformsNupur, Neh; Joshi, Srishti; Guillarme, Davy; Rathore, Anurag S.;
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Anion-Exchange Chromatography at the Service of Gene Therapy: Baseline Separation of Full/Empty Adeno-Associated Virus Capsids by Screening of Conditions and Step Gradient Elution ModeAebischer, Megane Klothylde; Gizardin-Fredon, Hugo; Lardeux, Honorine; Kochardt, Dominik; ... D'Atri, Valentina
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Antibiofilm Synergistic Activity of Streptomycin in Combination with Thymol-Loaded Poly (Lactic-co-glycolic Acid) Nanoparticles against Klebsiella pneumoniae IsolatesNdezo Bisso, Borel; Tokam Kuaté, Christian Ramsès; Boulens, Nathalie; Allémann, Eric; ... Dzoyem, Jean Paul
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Automated Hydrophobic Interaction Chromatography Screening Combined with In Silico Optimization as a Framework for Nondenaturing Analysis and Purification of BiopharmaceuticalsBarrientos, Rodell C.; Losacco, Gioacchino Luca; Azizi, Mohammadmehdi; Wang, Heather; ... Haidar Ahmad, Imad A.
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Bioadhesive Hyaluronic Acid/Dopamine Hydrogels for Vascular Applications Prepared by Initiator-Free CrosslinkingMelnik, Tamara; Ben Ameur, Senda; Kanfar, Nasreddine; Vinet, Laurent; ... Jordan, Olivier
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Bioadhesive Perivascular Microparticle-Gel Drug Delivery System for Intimal Hyperplasia Prevention: In Vitro Evaluation and Preliminary Biocompatibility AssessmentMelnik, Tamara; Porcello, Alexandre; Saucy, François; Delie Salmon, Florence; Jordan, Olivier
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Bispecific antibody characterization by a combination of intact and site-specific/chain-specific LC/MS techniquesDuivelshof, Bastiaan; Debecker, Alain; Guillarme, Davy; D'Atri, Valentina;
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Boosting the Liquid Chromatography Separation of Complex Bispecific Antibody Products by Using the Multi-Isocratic Elution ModeMurisier, Amarande; D'Atri, Valentina; Larraillet, Vincent; Pirner, Sebastian; Guillarme, Davy
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Case report: Confirming a diagnosis of severe olmesartan-associated enteropathyRoulet, Lucien; Bedatsova, Lucia; Merz, Laurent; Desmeules, Jules Alexandre; Saiah, Lila
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CEMIP ( HYBID , KIAA1199 ): structure, function and expression in health and diseaseSpataro, Sofia Carmen Suzanne; Guerra, Concetta; Cavalli, Andrea; Sgrignani, Jacopo; ... Prunotto, Marco
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Challenges in ESI-MS-based Untargeted MetabolomicsTobolkina, Elena; Gonzalez Ruiz, Victor; Meister, Isabel; De Figueiredo, Miguel; ... Rudaz, Serge
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Chemoenzymatic synthesis of complex phenylpropanoid derivatives by the Botrytis cinerea secretome and evaluation of their wnt inhibition activityHuber, Robin; Marcourt, Laurence; Koval, Alexey; Schnee, Sylvain; ... Ferreira Queiroz, Emerson
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Chemoenzymatic synthesis of original stilbene dimers possessing wnt inhibition activity in triple-negative breast cancer cells using the enzymatic secretome of Botrytis cinerea persHuber, Robin; Koval, Alexey; Marcourt, Laurence; Heritier, Margaux; ... Ferreira Queiroz, Emerson
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Chiral separation of stilbene dimers generated by biotransformation for absolute configuration determination and antibacterial evaluationHuber, Robin; Marcourt, Laurence; Quiros Guerrero, Luis Manuel; Luscher, Alexandre; ... Ferreira Queiroz, Emerson
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Circadian rhythm of lipid metabolismSinturel, Flore; Spaleniak, Weronika Karolina; Dibner, Charna;
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Combination of mesenchymal stem cells and bioactive molecules in hydrogels for osteoarthritis treatmentGonzalez Fernandez, Paula; Rodriguez-Nogales, Carlos; Jordan, Olivier; Allémann, Eric;
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Design, Synthesis, and Anticancer Activity of a Selenium‐Containing Galectin‐3 and Galectin‐9N InhibitorGervasio, Francesco Luigi; Galdadas, Yiannis; Di Gaetano, Sophia; Pirone, Luciano; ... Capasso, Domenica
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Development and application of a liquid chromatography coupled to mass spectrometry method for the simultaneous determination of 23 antineoplastic drugs at trace levelsFleury, Sandrine; Maurin, J; Guillarme, Davy; Rudaz, Serge; Bonnabry, Pascal
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Development and assessment of PharmaCheck: an electronic screening tool for the prevention of twenty major adverse drug eventsSkalafouris, Christian; Reny, Jean-Luc; Stirnemann, Jérôme; Grosgurin, Olivier; ... Guignard, Bertrand
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Dexamethasone exposure in normal-weight and obese hospitalized COVID-19 patients: An observational exploratory trialAbouir, Kenza; Gosselin, Pauline; Guerrier, Stéphane; Daali, Youssef; ... Ing Lorenzini, Kuntheavy
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Digoxin Induces Human Astrocyte Reaction In VitroPamies, David; Vujic, Tatjana; Schvartz, Domitille; Boccard, Julien; ... Zurich, Marie-Gabrielle
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Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody productsMurisier, Amarande; Andrie, Marie Josette Luce; Fekete, Szabolcs; Lauber, Matthew; ... Guillarme, Davy
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Discovery of anti-Formin-like 1 protein (FMNL1) antibodies in membranous nephropathy and other glomerular diseasesBruschi, Maurizio; Cavalli, Andrea; Moll, Solange; Candiano, Giovanni; ... Prunotto, Marco
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Editorial: Precision Medicine: Impact of Cytochromes P450 and Transporters Genetic Polymorphisms, Drug-Drug Interactions, Disease on Safety and Efficacy of DrugsDaali, Youssef; Rostami, Amin; Samer, Caroline Flora;
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Efficiently handling high‐dimensional data from multifactorial designs with unequal group sizes using Rebalanced ASCA (RASCA)De Figueiredo, Miguel; Giannoukos, Stamatios; Rudaz, Serge; Zenobi, Renato; Boccard, Julien
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Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6-hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spotsMagliocco, Gaëlle; Desmeules, Jules Alexandre; Samer, Caroline Flora; Thomas, Aurélien; Daali, Youssef
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Expediting the chromatographic analysis of COVID-19 antibody therapeutics with ultra-short columns, retention modeling and automated method developmentDuivelshof, Bastiaan; Zöldhegyi, Arnold; Guillarme, Davy; Lauber, Matthew; Fekete, Szabolcs
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Exploring the Reasons Behind the Substantial Discontinuation Rate Among Patients Taking CT-P13 in a Large Tertiary Hospital in Western Switzerland: A Retrospective Cohort Study Using Routinely Collected Medical DataKrstic, Marko; Devaud, Jean-Christophe; Marti, Joachim; Sadeghipour, Farshid;
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Extending the performance of FcRn and FcγRIIIa affinity liquid chromatography for protein biopharmaceuticalsBouvarel, Thomas; Duivelshof, Bastiaan; Camperi, Julien; Schlothauer, Tilman; ... Guillarme, Davy
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Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapyvan Beijnum, Judy R.; Huijbers, Elisabeth J. M.; van Loon, Karlijn; Blanas, Athanasios; ... Griffioen, Arjan W.
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Fast Optimization of Supercritical Fluid Chromatography–Mass Spectrometry Interfacing Using Prediction EquationsPlachká, Kateřina; Gazárková, Tat’ána; Škop, Jan; Guillarme, Davy; ... Novakova, Lucie
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Fecal microbiota transplantation: a review on current formulations in Clostridioides difficile infection and future outlooksRakotonirina, Mandimbinomena Adèle; Galperine, Tatiana; Allémann, Eric;
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Fluorescence Sensors Based on Hydroxycarbazole for the Determination of Neurodegeneration-Related Halide AnionsGonzalez Ruiz, Victor; Cores, Ángel; Caja, M. Mar; Sridharan, Vellaisamy; ... Menéndez, J. Carlos
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FOLFOXIRI Resistance Induction and Characterization in Human Colorectal Cancer CellsRamzy, George Mourad; Boschung, Laura; Kossler, Thibaud; Delucinge, Céline; ... Nowak-Sliwinska, Patrycja
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Full-scale simulations to improve disaster preparedness in hospital pharmaciesSchumacher, Laurence; Senhaji, Salim; Gartner, Birgit Andrea; Carrez, Laurent; ... Widmer, Nicolas
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Hydromorphone Prescription for Pain in Children - What Place in Clinical Practice?Rodieux, Frédérique; Ivanyuk, Anton; Besson, Marie; Desmeules, Jules Alexandre; Samer, Caroline Flora
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Impact of the Genotype and Phenotype of CYP3A and P-gp on the Apixaban and Rivaroxaban Exposure in a Real-World SettingLenoir, Camille; Terrier, Jean; Gloor, Yvonne Sylvia; Gosselin, Pauline; ... Rollason, Victoria
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Inhibition of IL-1β release from macrophages targeted with necrosulfonamide-loaded porous nanoparticlesBoersma, Bart Nicolaas; Möller, Karin; Wehl, Lisa; Puddinu, Viola; ... Bein, Thomas
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Internal calibration as an emerging approach for endogenous analyte quantification: Application to steroidsVisconti, Gioele; Olesti, Eulalia; Gonzalez Ruiz, Victor; Glauser, Gaëtan; ... Rudaz, Serge
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Interventions to Support Adherence to Oral Anticancer Therapies: Research challenges, lessons learned, and strategies to overcome them from Australia and SwitzerlandBandiera, Carole; Skrabal Ross, Xiomara; Cardoso, Evelina; Wagner, Dorothea; ... Schneider Voirol, Marie Paule
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Medication adherence evaluated through electronic monitors during the 2020 COVID-19 pandemic lockdown in Switzerland: a longitudinal analysisBandiera, Carole; Pasquier, Jérôme; Locatelli, Isabella; Niquille, Anne; ... Schneider Voirol, Marie Paule
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Metabolomics in Ecology and Bioactive Natural Products Discovery: Challenges and Prospects for a Comprehensive Study of the Specialised MetabolomeWolfender, Jean-Luc; Gaudry, Arnaud; Rutz, Adriano; Quiros Guerrero, Luis Manuel; ... Allard, Pierre-Marie
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Nanoforming hyaluronan-based thermoresponsive hydrogels: optimized and tunable functionality in osteoarthritis managementPorcello, Alexandre; Gonzalez Fernandez, Paula; Jordan, Olivier; Allémann, Eric;
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Oxidative Stress and Extracellular Matrix Remodeling Are Signature Pathways of Extracellular Vesicles Released upon Morphine Exposure on Human Brain Microvascular Endothelial CellsVujic, Tatjana; Schvartz, Domitille; Furlani, Izadora; Meister, Isabel; ... Sanchez, Jean-Charles
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Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondiiLunghi, Matteo; Kloehn, Joachim; Krishnan, Aarti; Varesio, Emmanuel; ... Soldati-Favre, Dominique
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Patients’ perceptions of conflicting information on chronic medications: a prospective survey in SwitzerlandSantos, Beatriz; Blondon, Katherine S; Van Gessel, Elisabeth; Cerutti, Bernard; ... Schneider Voirol, Marie Paule
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PEGylated Gold Nanoparticles Target Age-Associated B Cells In VivoHocevar, Sandra; Puddinu, Viola; Haeni, Laetitia; Petri-Fink, Alke; ... Bourquin, Carole
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Pharmaceutical interventions on hospital discharge prescriptions: Prospective observational study highlighting challenges for community pharmacistsGrandchamp, Sophie; Blanc, Anne-Laure; Roussel, Marine Aurore Elodie; Tagan, Damien; ... Widmer, Nicolas
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Pharmacological prevention of intimal hyperplasia: A state-of-the-art reviewMelnik, Tamara; Jordan, Olivier; Corpataux, Jean-Marc; Delie Salmon, Florence; Saucy, François
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Polyethylenimine/cGAMP Nanocomplexes for STING-Mediated Cancer Immunotherapy: Formulation and Characterization Using Orthogonal TechniquesPetrovic, Marija; Borchard, Gerrit; Jordan, Olivier;
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Population pharmacokinetics of palbociclib and its correlation with clinical efficacy and safety in patients with advanced breast cancerCourlet, Perrine; Cardoso, Evelina; Bandiera, Carole; Stravodimou, Athina; ... Csajka, Chantal
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Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokineticsLenoir, Camille; Niederer, Amine; Rollason, Victoria; Desmeules, Jules Alexandre; ... Samer, Caroline Flora
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Preventing Antibiotic-Resistant Infections: Additively Manufactured Porous Ti6Al4V Biofunctionalized with Ag and Fe NanoparticlesPutra, Niko E; Leeflang, Marius A; Ducret, Verena; Patrulea, Viorica; ... Zadpoor, Amir A
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Primary cilia control endothelial permeability by regulating expression and location of junction proteinsDiagbouga, Mannekomba Roxane; Morel, Sandrine; Cayron, Anne France Judith; Haemmerli, Julien; ... Kwak, Brenda
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Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergyNowak-Sliwinska, Patrycja; van Beijnum, Judy R; Griffioen, Christian J; Huinen, Zowi R; ... Griffioen, Arjan W
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Separation and determination of cysteine enantiomers in plasma after derivatization with 4-fluoro-7-nitrobenzofurazanFerre, Sabrina Myriam; Gonzalez Ruiz, Victor; Zangari, Josephine; Girel, Sergey; ... Rudaz, Serge
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Sub/supercritical fluid chromatography versus liquid chromatography for peptide analysisDeidda, Riccardo; Losacco, Gioacchino Luca; Schelling, Cédric; Regalado, Erik L.; ... Guillarme, Davy
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Swiss priority setting on implementing medication adherence interventions as part of the European ENABLE COST actionBandiera, Carole; Ribaut, Janette; Dima, Alexandra L.; Allemann, Samuel S.; ... Schneider Voirol, Marie Paule
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Synergistic effects of antimicrobial peptide dendrimer-chitosan polymer conjugates against Pseudomonas aeruginosaPatrulea, Viorica; Gan, Bee-Ha; Perron, Karl; Cai, Xingguang; ... Jordan, Olivier
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Synthesis, Formulation and Characterization of Immunotherapeutic Glycosylated Dendrimer/cGAMP Complexes for CD206 Targeted Delivery to M2 Macrophages in Cold TumorsPetrovic, Marija; Porcello, Alexandre; Tankov, Stoyan; Majchrzak, Oliwia Barbara; ... Jordan, Olivier
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Target Metabolome Profiling-Based Machine Learning as a Diagnostic Approach for Cardiovascular Diseases in AdultsMoskaleva, Natalia E; Shestakova, Ksenia M; Kukharenko, Alexey V; Markin, Pavel A; ... Appolonova, Svetlana A
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Teg58, a small regulatory RNA, is involved in regulating arginine biosynthesis and biofilm formation in Staphylococcus aureusManna, Adhar C.; Leo, Stefano; Girel, Sergey; Gonzalez Ruiz, Victor; ... Cheung, Ambrose L.
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The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotidesLardeux, Honorine; Goyon, Alexandre; Zhang, Kelly; Nguyen, Jennifer M; ... D'Atri, Valentina
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The LOTUS initiative for open knowledge management in natural products researchRutz, Adriano; Sorokina, Maria; Galgonek, Jakub; Mietchen, Daniel; ... Allard, Pierre-Marie
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The safe handling of chemotherapy drugs in low- and middle-income countries: An overview of practicesVon Grunigen, Sandrine; Geissbuhler, Antoine; Bonnabry, Pascal;
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Trapping‐Enrichment Multi‐dimensional Liquid Chromatography with On‐Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram ScaleAhmad, Imad A. Haidar; Losacco, Gioacchino Luca; Shchurik, Vladimir; Wang, Xiao; ... Regalado, Erik L.
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Ultra-fast middle-up reversed phase liquid chromatography analysis of complex bispecific antibodies obtained in less than one minuteMurisier, Amarande; D'Atri, Valentina; Pirner, Sebastian; Larraillet, Vincent; ... Guillarme, Davy
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Zinc homeostasis in PseudomonasDucret, Verena; Gonzalez, Diego; Perron, Karl;

Professional Articles

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Austrittsrezepte: pharmazeutische Interventionen in der OffizinDobrinas-Bonazzi, Maria; Grandchamp, Sophie; Roussel, Marine Aurore Elodie; Blanc, Anne-Laure; Widmer, Nicolas

Books

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Microworld : Voyage au centre du microbiote intestinalWeber, Aurélia; Perron, Karl;

Book Chapters

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Application space for SFC in pharmaceutical drug discovery and developmentLosacco, Gioacchino Luca; Dispas, Amandine; Veuthey, Jean-Luc; Guillarme, Davy;
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Evaluation of Prototype CE-MS InterfacesFerre, Sabrina Myriam; Boccard, Julien; Rudaz, Serge; Gonzalez Ruiz, Victor;

Doctoral Thesis

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Anti-proliferative Natural Compounds and their Derivatives in various in vitro Multiple Myeloma ModelsFaria Freitas Misakyan, Micaela;
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Approches pédagogiques innovantes sur la sécurité d’utilisation des médicaments : création et évaluation de formations pour les professionnels de santé hospitaliers et d’une action de sensibilisation pour les patientsFlornoy, Audrey Marie Angélique;
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Comprehensive Study of the Fungal Endophyte Community of the Long-lived Amazonian Palm Astrocaryum Sciophilum: A Model for Deciphering Plant-microbe Interactions at Chemical and Bioactive LevelsPellissier, Léonie;
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Conception, évaluation et impact d'une aide à la décision informatisée destinée aux pharmaciens cliniciensSkalafouris, Christian;
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Controlled drug delivery systems for perivascular application and intimal hyperplasia preventionMelnik, Tamara;
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Cytochrome P450 Activity Assessment: Toward Validation of Endogenous Metrics and Discovery of New Biomarkers Using Untargeted MetabolomicsMagliocco, Gaëlle;
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Design of STING ligand nanoparticles for improved cold cancer immunotherapyPetrovic, Marija;
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Development and Validation of Automatic Tools to Improve Adverse Drug Event Management in Hospitalised Older PatientsLisibach, Angela Edith;
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Development of liquid chromatographic techniques and their possible hyphenation to mass spectrometry for therapeutic protein characterizationMurisier, Amarande;
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Development of new formulation strategies for targeted drug delivery of low and high molecular weight therapeutic agentsDarade, Aditya Ramnath;
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Exploring Metabolic Alterations in Cancer for Photodynamic PurposesKiening, Martin;
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Genetic and multidrug combinatorial screens unravel new mechanistic clues and optimised therapeutics for estrogen receptor alpha-mediated breast cancerHany, Dina;
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Hyaluronan-Based Hydrogel Formulations for Therapeutic ApplicationsPorcello, Alexandre;
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Integrative Analytical and Computational Strategies for Qualitative and Semi-quantitative Plant Metabolome CharacterizationRutz, Adriano;
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Jasmonate pathway initiation in the distal leaf primary vasculature after mechanical wounding in Arabidopsis thalianaMorin, Hugo;
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Nanofitin as a novel shuttle for oral delivery of biologicsMasloh, Solene Nisrine Coraline;
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Optimisation de la pharmacothérapie aux soins intensifs de pédiatrie et de néonatologie : le rôle des recommandations de bonnes pratiques cliniquesVon Rohr, Thomas;
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Photosensitizer prodrug-induced protein expression in cancer cellsSansaloni Pastor, Sara;
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Precision medicine: a phenotypic perspective on drug safety through clinical trials in hospitalized patientsLenoir, Camille;
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Role of Intratumoral HMGB1 in the Antitumor Immune ResponseTaskoparan Yaglikci, Betul;
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