Section des sciences pharmaceutiques

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2020

Scientific Articles

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A combined activation mechanism for the glucagon receptorMattedi, Giulio; Acosta-Gutiérrez, Silvia; Clark, Timothy; Gervasio, Francesco Luigi;
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An Adherence-Enhancing Program Increases Retention in Care in the Swiss HIV CohortKamal, Susan; Glass, Tracy R; Doco-Lecompte, Thanh; Locher, Sophie; ... Schneider Voirol, Marie Paule
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An Update on Antimicrobial Peptides (AMPs) and Their Delivery Strategies for Wound InfectionsPatrulea, Viorica; Borchard, Gerrit; Jordan, Olivier;
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Antiproliferative activity of a new xanthone derivative from leaves of Garcinia nobilis EnglFouotsa, Hugues; Dzoyem, Jean Paul; Lannang, Alain Meli; Stammler, Hans-Georg; ... Sewald, Norbert
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Antiseizure potential of the ancient Greek medicinal plant Helleborus odorus subsp. cyclophyllus and identification of its main active principlesBrillatz, Théo; Jacmin, Maxime; Vougogiannopoulou, Konstantina; Petrakis, Eleftherios A.; ... Wolfender, Jean-Luc
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Applicability of Supercritical fluid chromatography–Mass spectrometry to metabolomics. II–Assessment of a comprehensive library of metabolites and evaluation of biological matricesLosacco, Gioacchino Luca; Ismail, Omar; Pezzatti, Julian; Gonzalez Ruiz, Victor; ... Guillarme, Davy
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Are Antimicrobial Peptide Dendrimers an Escape from ESKAPE?Kawano, Yayoi; Jordan, Olivier; Hanawa, Takehisa; Borchard, Gerrit; Patrulea, Viorica
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Automated middle-up approach for the characterization of biotherapeutic products by combining on-line hinge-specific digestion with RPLC-HRMS analysisCamperi, Julien; Guillarme, Davy; Lei, Ming; Stella, Cinzia;
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Bacterial cell cycle control by citrate synthase independent of enzymatic activityBerge, Matthieu; Pezzatti, Julian; Gonzalez Ruiz, Victor; Degeorges, Laurence; ... Viollier, Patrick
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Capillary Electrophoresis-Mass Spectrometry at Trial by Metabo-Ring: Effective Electrophoretic Mobility for Reproducible and Robust Compound AnnotationDrouin, Nicolas; van Mever, Marlien; Zhang, Wei; Tobolkina, Elena; ... Ramautar, Rawi
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Comparison of Bioinformatics Pipelines and Operating Systems for the Analyses of 16S rRNA Gene Amplicon Sequences in Human Fecal SamplesMarizzoni, Moira; Gurry, Thomas; Provasi, Stefania; Greub, Gilbert; ... Cattaneo, Annamaria
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Comprehensive Examination of the Mouse Lung Metabolome Following Mycobacterium tuberculosis Infection Using a Multiplatform Mass Spectrometry ApproachFernández-García, Miguel; Rey-Stolle, Fernanda; Boccard, Julien; Reddy, Vineel P.; ... Barbas, Coral
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Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33Rouaud, Florian; Tessaro, Francesca; Aimaretti, Laura; Scapozza, Leonardo; Citi, Sandra
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Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related productsFarsang, Evelin; Guillarme, Davy; Veuthey, Jean-Luc; Beck, Alain; ... Fekete, Szabolcs
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Cultivar, site or harvest date: the gordian knot of wine terroirSchmidtke, L. M.; Antalick, G.; Šuklje, K.; Blackman, J. W.; ... Deloire, A.
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Current and future trends in reversed-phase liquid chromatography-mass spectrometry of therapeutic proteinsD'Atri, Valentina; Murisier, Amarande; Fekete, Szabolcs; Veuthey, Jean-Luc; Guillarme, Davy
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Cytotoxicity of a new tirucallane derivative isolated from Stereospermum acuminatissimum K. Schum stem barkLeutcha, Bosco Peron; Sema, Denis Kehdinga; Dzoyem, Jean Paul; Ayimele, Godfred Aponglen; ... Meli Lannang, Alain
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Deprescribing in nursing homes: Protocol for nested, randomised controlled hybrid trials of deprescribing interventionsCateau, Damien; Ballabeni, Pierluigi; Mena, Stéphanie; Bugnon, Olivier Jean; Niquille, Anne
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Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificitiesWagner, Elsa; Colas, Olivier; Chenu, Stéphane; Goyon, Alexandre; ... Beck, Alain
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Development and validation of a chiral UHPLC-MS method for the analysis of cysteine enantiomers in biological samplesPucciarini, Lucia; Gonzalez Ruiz, Victor; Zangari, Josephine; Martinou, Jean-Claude; ... Rudaz, Serge
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Development of a 3D-LC/MS Workflow for Fast, Automated, and Effective Characterization of Glycosylation Patterns of Biotherapeutic ProductsCamperi, Julien; Dai, Lu; Guillarme, Davy; Stella, Cinzia;
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Development of an innovative salt-mediated pH gradient cation exchange chromatography method for the characterization of therapeutic antibodiesGoyon, Alexandre; McDonald, Daniel; Fekete, Szabolcs; Guillarme, Davy; Stella, Cinzia
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Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma TreatmentZoetemelk, Marloes; Ramzy, George Mourad; Rausch, Magdalena; Nowak-Sliwinska, Patrycja;
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E-Learning Training to Improve Pediatric Parenteral Nutrition Practice: A Pilot Study in Two University HospitalsPetit, Laëtitia Marie; Le Pape, Pauline; Delestras, Stephanie; Nguyen, Christina; ... Fonzo-Christe, Caroline Cécile
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Editorial for the special issue titled "Biopharmaceuticals 2020"Fekete, Szabolcs; Guillarme, Davy;
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Editorial for the virtual special issue SEP 2019Guillarme, Davy; West, Caroline;
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Electromembrane Extraction of Highly Polar Compounds: Analysis of Cardiovascular Biomarkers in PlasmaDrouin, Nicolas; Kloots, Tim; Schappler, Julie; Rudaz, Serge; ... Hankemeier, Thomas
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Enhancing ovarian cancer conventional chemotherapy through the combination with cannabidiol loaded microparticlesFraguas-Sánchez, A.I.; Fernández-Carballido, A.; Delie Salmon, Florence; Cohen, Marie-Benoîte; ... Torres-Suárez, A.I.
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Evaluation of additives on reversed-phase chromatography of monoclonal antibodies using a 1000 Å stationary phaseMcCalley, David V.; Guillarme, Davy;
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Evaluation of Different Tandem MS Acquisition Modes to Support Metabolite Annotation in Human Plasma Using Ultra High-Performance Liquid Chromatography High-Resolution Mass Spectrometry for Untargeted MetabolomicsPezzatti, Julian; Gonzalez Ruiz, Victor; Boccard, Julien; Guillarme, Davy; Rudaz, Serge
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Evaluation of ion mobility in capillary electrophoresis coupled to mass spectrometry for the identification in metabolomicsDrouin, Nicolas; Mielcarek, Andreas; Wenz, Christian; Rudaz, Serge;
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Evolution of potentially inappropriate medication use in nursing homes: Retrospective analysis of drug consumption dataCateau, Damien; Bugnon, Olivier Jean; Niquille, Anne;
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Fast and Automated Characterization of Monoclonal Antibody Minor Variants from Cell Cultures by Combined Protein-A and Multidimensional LC/MS MethodologiesCamperi, Julien; Dai, Lu; Guillarme, Davy; Stella, Cinzia;
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From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterization of therapeutic antibodiesGoyon, Alexandre; Dai, Lu; Chen, Tao; Wei, Bingchuan; ... Stella, Cinzia
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Functional and computational genomics reveal unprecedented flexibility in stage-specific Toxoplasma metabolismKrishnan, Aarti; Kloehn, Joachim; Lunghi, Matteo; Chiappino-Pepe, Anush; ... Soldati-Favre, Dominique
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Gestion de la pandémie COVID-19 en Suisse : rôles et défis d’une pharmacie interhospitalièreSchumacher, Laurence; Blatrie, Cédric; Krähenbühl, Séverine; Pasteur, Camilla; ... Widmer, Nicolas
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Glycan-Mediated Technology for Obtaining Homogeneous Site-Specific Conjugated Antibody-Drug Conjugates: Synthesis and Analytical Characterization by Using Complementary Middle-up LC/HRMS AnalysisDuivelshof, Bastiaan; Deslignière, Evolène; Hernandez-Alba, Oscar; Ehkirch, Anthony; ... D'Atri, Valentina
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How the Lack of Chitosan Characterization Precludes Implementation of the Safe-by-Design ConceptMarques, Cintia; Som, Claudia; Schmutz, Mélanie; Borges, Olga; Borchard, Gerrit
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Identification of anti-mycobacterium and anti-legionella compounds with potential distinctive structural scaffolds from an HD-PBL using phenotypic screens in amoebae host modelsHanna, Nabil; Kicka, Sébastien; Chiriano, Gianpaolo; Harrison, Christopher; ... Soldati, Thierry
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Identification of low-dose multidrug combinations for sunitinib-naive and pre-treated renal cell carcinomaRausch, Magdalena; Weiss, Andrea; Achkhanian, Joanna; Rotari, Andrei; Nowak-Sliwinska, Patrycja
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Impact of the column on effluent pH in cation exchange pH gradient chromatography, a practical studyFarsang, Evelin; Horváth, Krisztián; Beck, Alain; Wang, Qi; ... Fekete, Szabolcs
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Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorialPezzatti, Julian; Boccard, Julien; Codesido, Santiago; Gagnebin, Yoric; ... Rudaz, Serge
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Improving selectivity and performing online on-column fractioning in liquid chromatography for the separation of therapeutic biopharmaceutical productsFekete, Szabolcs; Ritchie, Harald; Lawhorn, Jason; Veuthey, Jean-Luc; Guillarme, Davy
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In Vitro Anti-Inflammatory Activity in Arthritic Synoviocytes of A. brachypoda Root Extracts and Its Unusual Dimeric FlavonoidsDe Lacerda Salgado, Carlota; Morin, Hugo; Coriolano de Aquino, Nayara; Neff, Laurence Anne; ... Allémann, Eric
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Inhibition of enteric methanogenesis in dairy cows induces changes in plasma metabolome highlighting metabolic shifts and potential markers of emissionYanibada, Bénédict; Hohenester, Ulli; Pétéra, Mélanie; Canlet, Cécile; ... Boudra, Hamid
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Insights on the Structural and Metabolic Resistance of Potato (Solanum tuberosum) Cultivars to Tuber Black Dot (Colletotrichum coccodes)Massana Codina, Josep; Schnee, Sylvain; Allard, Pierre-Marie; Rutz, Adriano; ... Wolfender, Jean-Luc
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Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatmentvan Beijnum, Judy R; Weiss, Andrea; Berndsen, Robert H.; Wong, Tse J; ... Nowak-Sliwinska, Patrycja
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Interlaboratory and Interplatform Study of Steroids Collision Cross Section by Traveling Wave Ion Mobility SpectrometryHernández-Mesa, Maykel; D'Atri, Valentina; Barknowitz, Gitte; Fanuel, Mathieu; ... Le Bizec, Bruno
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Investigating the use of unconventional temperatures in supercritical fluid chromatographyLosacco, Gioacchino Luca; Fekete, Szabolcs; Veuthey, Jean-Luc; Guillarme, Davy;
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Is pain temporary and glory forever? Detection of tramadol using dried blood spot in cycling competitionsSalamin, Olivier; Garcia, Arnaud; Gonzalez Ruiz, Victor; Rossi, Francesca; ... Rudaz, Serge
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Metabolomics approach reveals disruption of metabolic pathways in the marine bivalve Mytilus galloprovincialis exposed to a WWTP effluent extractDumas, Thibaut; Bonnefille, Bénilde; Gomez, Elena; Boccard, Julien; ... Courant, Frédérique
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Multifactorial Analysis of Environmental Metabolomic Data in Ecotoxicology: Wild Marine Mussel Exposed to WWTP Effluent as a Case StudyDumas, Thibaut; Boccard, Julien; Gomez, Elena; Fenet, Hélène; Courant, Frédérique
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Nano wet milled celecoxib extended release microparticles for local management of chronic inflammationSalgado, Carlota; Guénée, Laure; Černý, Radovan; Allémann, Eric; Jordan, Olivier
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Non-invasive targeted iontophoretic delivery of cetuximab to skinLapteva, Maria; Sallam, Marwa A.; Goyon, Alexandre; Guillarme, Davy; ... Kalia, Yogeshvar
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Ocular Biodistribution of Spironolactone after a Single Intravitreal Injection of a Biodegradable Sustained-Release Polymer in RatsDahmana, Naoual; Kowalczuk, Laura; Gabriel, Doris; Behar-Cohen, Francine; ... Kalia, Yogeshvar
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Optimization for multidrug combinations: Challenges and perspectives in complex disordersNowak-Sliwinska, Patrycja;
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Optimized Combination of HDACI and TKI Efficiently Inhibits Metabolic Activity in Renal Cell Carcinoma and Overcomes Sunitinib ResistanceRausch, Magdalena; Weiss, Andrea; Zoetemelk, Marloes; Piersma, Sander R; ... Nowak-Sliwinska, Patrycja
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Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatmentZoetemelk, Marloes; Ramzy, George Mourad; Rausch, Magdalena; Kossler, Thibaud; ... Nowak-Sliwinska, Patrycja
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Optimized one-pot derivatization and enantioseparation of cysteine: Application to the study of a dietary supplementPucciarini, Lucia; Saluti, Giorgio; Galarini, Roberta; Carotti, Andrea; ... Sardella, Roccaldo
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Patient-Derived In Vitro Models for Drug Discovery in Colorectal CarcinomaRamzy, George Mourad; Koessler, Thibaud; Ducrey, Eloise; Mckee, Thomas Alexander; ... Nowak-Sliwinska, Patrycja
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Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6Balaphas, Alexandre; Meyer, Jérémy; Perozzo, Remo; Zeisser-Labouebe, Magali; ... Buehler, Leo Hans
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PLGA Nanoparticles for the Intraperitoneal Administration of CBD in the Treatment of Ovarian Cancer: In Vitro and In Ovo AssessmentFraguas-Sánchez, Ana I.; Torres-Suárez, Ana I.; Cohen, Marie-Benoîte; Delie Salmon, Florence; ... Fernández-Carballido, Ana
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Population pharmacokinetics of erlotinib in patients with non-small cell lung cancer: Its application for individualized dosing regimens in older patientsCardoso, Evelina; Guidi, Monia; Khoudour, Nihel; Boudou-Rouquette, Pascaline; ... Csajka, Chantal
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Production of Highly Active Antiparasitic Compounds from the Controlled Halogenation of the Arrabidaea brachypoda Crude Plant ExtractNeuenschwander, Alexandra; Rocha, Vinicius P. C.; Bastos, Tanira M.; Marcourt, Laurence; ... Ferreira Queiroz, Emerson
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Profiling of anabolic androgenic steroids and selective androgen receptor modulators for interference with adrenal steroidogenesisPatt, Melanie; Beck, Katharina R.; Di Marco, Tobias; Jäger, Marie-Christin; ... Odermatt, Alex
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Programmed death, cells on the last train to gloryNowak-Sliwinska, Patrycja; Griffioen, Arjan W;
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Reshaping the LandscapeGuillarme, Davy; Koen, Sandra;
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Satisfaction and experiences of patients taking fingolimod and involved in a pharmacy-based patient support program in Switzerland — a qualitative studyBourdin, Aline; Dubois, Julie; Foley, Rose-Anna; Schluep, Myriam; ... Berger, Jérôme
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Semen endocannabinoids are correlated to sperm quality in a cohort of 200 young Swiss menZufferey, Fanny; Donzé, Nicolas; Rahban, Rita; Senn, Alfred Paul; ... Rossier, Michel
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Silver-Containing Titanium Dioxide Nanocapsules for Combating Multidrug-Resistant BacteriaHérault, Nelly; Wagner, Julia; Abram, Sarah-Luise; Widmer, Jérôme; ... Fromm, Katharina M
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Steroid profile analysis by LC-HRMS in human seminal fluidOlesti, Eulalia; Garcia, Arnaud; Rahban, Rita; Rossier, Michel; ... Rudaz, Serge
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Supercritical fluid chromatography – Mass spectrometry in metabolomics: Past, present, and future perspectivesvan de Velde, Bas; Guillarme, Davy; Kohler, Isabelle;
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Supercritical fluid chromatography–mass spectrometry in routine anti-doping analyses: Estimation of retention time variability under reproducible conditionsLosacco, Gioacchino Luca; Marconetto, Elisa; Nicoli, Raul; Kuuranne, Tiia; ... Guillarme, Davy
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Surface sensing triggers a broad-spectrum antimicrobial response in Pseudomonas aeruginosaGdaniec, Bartosz Gérard; Allard, Pierre-Marie; Ferreira Queiroz, Emerson; Wolfender, Jean-Luc; ... Kohler, Thilo
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Swiss Armed Forces deployment during the COVID-19 pandemic: militia pharmacy officers' roles and dutiesWidmer, Nicolas; Abbet, Christian; Brunner, Joël; Faro Barros, Jonathan; ... Herklotz, Roberto
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Targeted Bottom-up Characterization of Recombinant Monoclonal Antibodies by Multidimensional LC/MSCamperi, Julien; Guillarme, Davy; Stella, Cinzia;
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Targeted cutaneous delivery of etanercept using Er:YAG fractional laser ablationDel Río-Sancho, Sergio; Lapteva, Maria; Sonaje, Kiran; Böhler, Christof; ... Kalia, Yogeshvar
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The analysis of cannabinoids in cannabis samples by supercritical fluid chromatography and ultra‐high‐performance liquid chromatography: A comparison studyDeidda, Riccardo; Schelling, Cédric; Roussel, Jean‐Marc; Dispas, Amandine; ... Veuthey, Jean-Luc
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The CzcCBA efflux system requires the CadA P-type ATPase for timely expression upon zinc excess in pseudomonas aeruginosaDucret, Verena; Gonzalez, Manuel R.; Leoni, Sara; Valentini, Martina; Perron, Karl
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The steps to therapeutic drug monitoring: A structured approach illustrated with imatinibBuclin, Thierry; Thoma, Yann; Widmer, Nicolas; André, Pascal; ... Decosterd, Laurent
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Therapeutic drug monitoring of targeted anticancer protein kinase inhibitors in routine clinical use: A critical reviewCardoso, Evelina; Guidi, Monia; Blanchet, Benoît; Schneider Voirol, Marie Paule; ... Widmer, Nicolas
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Tissue Levels of Flurbiprofen in the Rat Plantar Heel after Short-Duration Topical Iontophoresis are Sufficient to Induce Pharmacodynamic Responses to Local Pain StimuliCai, Yilu; Zhou, Ye; Zhang, Peiyan; Kalia, Yogeshvar; ... Chen, Yong
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TOP-ID: a Delphi technique-guided development of a prescription and deprescription tool for adults with intellectual disabilitiesLonchampt, Sophie; Gerber, Fabienne Maria Y.; Aubry, Jean-Michel; Desmeules, Jules Alexandre; ... Kosel, Markus Mathaus
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Ultra‐high performance supercritical fluid chromatography coupled to tandem mass spectrometry for antidoping analyses: Assessment of the inter‐laboratory reproducibility with urine samplesLosacco, Gioacchino Luca; Rentsch, Marco; Plachká, Kateřina; Monteau, Fabrice; ... Guillarme, Davy
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Validation and Clinical Application of a Multiplex High Performance Liquid Chromatography - Tandem Mass Spectrometry Assay for the Monitoring of Plasma Concentrations of 12 Antibiotics in Patients with Severe Bacterial InfectionsDecosterd, Laurent; Mercier, Thomas; Ternon, Beatrice; Cruchon, Sandra; ... Marchetti, Oscar

Professional Articles

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Development and validation of an UHPLC–MS/MS method for extended serum steroid profiling in female populationsSalamin, Olivier; Ponzetto, Federico; Cauderay, Michel Jean; Boccard, Julien; ... Nicoli, Raul

Book Chapters

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Drug Loading and Distribution of ADCs After Reduction or IdeS Digestion and ReductionWagner-Rousset, Elsa; Colas, Olivier; François, Yannis-Nicolas; Heinisch, Sabine; ... Beck, Alain

Doctoral Thesis

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Application and evaluation of liquid chromatography - high resolution mass spectrometry in untargeted metabolomics for compound annotations in biological matricesPezzatti, Julian;
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Challenges and considerations in designing multidrug combinations for cancer treatmentZoetemelk, Marloes;
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Comprehensive chemical profiling for plant chemotaxonomy and quality control of herbal medicines – An MS-based metabolomics and molecular network perspectiveAfzan, Adlin;
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Epidemiological insights, cultivar resistance and natural products to control black dot (Colletotrichum coccodes) and silver scurf (Helminthosporium solani) on potato (Solanum tuberosum) tubersMassana Codina, Josep;
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L’adhésion aux guidelines chez les médecins et l’adhésion aux médicaments chez les patients dans le domaine de la cardiologie : état des lieux et stratégies d’optimisationBruggmann, Christel;
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Medicinal Plants to Treat Epilepsy: Discovery of Antiseizure Compounds by In Vivo Zebrafish Bioactivity-Guided IsolationBrillatz, Théo;
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