Département de chimie organique

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2020

Scientific Articles

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A Catalytic Dual Isomerization/Allylboration Sequence for the Stereoselective Construction of Congested Secondary Homoallylic AlcoholsLiu, Yangbin; Mazet, Clement;
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Caprin‐1 Promotes Cellular Uptake of Nucleic Acids with Backbone and Sequence DiscriminationGalli, Valentina; Sadhu, Kalyan Kumar; Masi, Daniela; Saarbach, Jacques; ... Winssinger, Nicolas
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Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane NetworksLopez Andarias, Javier; Saarbach, Jacques; Moreau, Dimitri; Cheng, Yangyang; ... Matile, Stefan
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Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9Plank, Michaël; Perepelkina, Mariya; Muller, Markus Johann; Vaga, Stefania; ... Loewith, Robbie Joséph
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Chiroptical detection of a model ruthenium dye in water by circularly polarized-electrochemiluminescenceVoci, Silvia; Zinna, Francesco; Arrico, Lorenzo; Grass, Stéphane; ... Sojic, Neso
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Direct Access to Chiral Secondary Amides by Copper-Catalyzed Borylative Carboxamidation of Vinylarenes with IsocyanatesFiorito, Daniele; Liu, Yangbin; Besnard, Céline; Mazet, Clement;
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Empowering Global Chemical Biology at the Dawn of the New DecadeHoogendoorn, Sascha; Aye, Yimon;
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Enantiopure encaged Verkade's superbases: Synthesis, chiroptical properties, and use as chiral derivatizing agentYang, Jian; Chatelet, Bastien; Hérault, Damien; Dufaud, Véronique; ... Martinez, Alexandre
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Enhanced SNP-sensing using DNA-templated reactions through confined hybridization of minimal substrates (CHOMS)Kim, Kitae; Winssinger, Nicolas;
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Everything you wanted to know about phase and reference frequency in one- and two-dimensional NMR spectroscopySheberstov, Kirill; Sistare Guardiola, Eduard; Jeannerat, Damien;
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From reactive carbenes to chiral polyether macrocycles in two steps – synthesis and applications made easy?Homberg, Alexandre; Lacour, Jérôme;
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Kilian Muñiz (1970–2020)Streuff, Jan; Echavarren, Antonio M.; González, José Manuel; Oestreich, Martin; ... Winssinger, Nicolas
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Mapping Cell Membrane Organization and Dynamics Using Soft Nanoimprint LithographySansen, T.; Sanchez-Fuentes, D.; Rathar, R.; Colom Diego, Adai; ... Picas, L.
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Mechanosensitive membrane probes: push-pull papillonsHumeniuk, Heorhii; Licari, Giuseppe Léonardo; Vauthey, Eric; Sakai, Naomi; Matile, Stefan
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Merging polyacenes and cationic helicenes: from weak to intense chiroptical properties in the far red regionDuwald, Romain; Bosson, Johann; Pascal, Simon; Grass, Stéphane; ... Lacour, Jérôme
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Methyl Scanning for Mechanochemical Chalcogen‐Bonding Cascade SwitchesZhang, Xiang; Sakai, Naomi; Matile, Stefan;
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Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion couplingOberhauser, Lucie; Granziera, Sabrina; Colom Diego, Adai; Goujon, Antoine; ... Maechler, Pierre
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Peptide Stapling with Anion‐π CatalystsPham, Anh Tuan; Matile, Stefan;
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Photo-induced thiol–ene reactions for late-stage functionalization of unsaturated polyether macrocycles: regio and diastereoselective access to macrocyclic dithiol derivativesBrun, Elodie; Zhang, Kefeng; Guenee, Laure; Lacour, Jérôme;
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PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectinsFarrera Soler, Lluc; Daguer, Jean Pierre; Raunft, PATRICK; Barluenga Badiola, Sofia; ... Winssinger, Nicolas
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Primary Anion–π Catalysis of Epoxide‐Opening Ether Cyclization into Rings of Different Sizes: Access to New ReactivityParaja, Miguel; Matile, Stefan;
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Probing for Thiol-Mediated Uptake into BacteriaLaurent, Quentin François Antoine; Berthet, Mathéo; Cheng, Yangyang; Sakai, Naomi; ... Matile, Stefan
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SAN plot: A graphical representation of the signal, noise, and artifacts content of spectraSheberstov, Kirill F.; Sistare Guardiola, Eduard; Pupier, Marion; Jeannerat, Damien;
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Self-enhanced multicolor electrochemiluminescence by competitive electron-transfer processesVoci, Silvia; Duwald, Romain; Grass, Stéphane; Hayne, David J.; ... Sojic, Neso
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Small-molecule modulators of the ATPase VCP/p97 affect specific p97 cellular functionsFiguerola Conchas, Ainoa; Saarbach, Jacques; Daguer, Jean Pierre; Cieren, Adeline; ... Gotta, Monica
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Smartphone DNA or RNA Sensing Using Semisynthetic Luciferase-Based Logic DeviceChang, Dalu; Kim, Kitae; Lindberg, Eric; Winssinger, Nicolas;
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Synthesis, characterization, catalytic and biological application of half-sandwich ruthenium complexes bearing hemilabile (κ2-C,S)-thioether-functionalised NHC ligandsChen, Weiguang; Egly, Julien; Poblador Bahamonde, Amalia Isabel; Maisse-Francois, Aline; ... Achard, Thierry
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Twisting and tilting of a mechanosensitive molecular probe detects order in membranesLicari, Giuseppe Léonardo; Strakova, Karolina; Matile, Stefan; Tajkhorshid, Emad;
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Untying the Photophysics of Quinolinium‐Based Molecular Knots and LinksCaprice, Kenji; Aster, Alexander; Cougnon, Fabien; Kumpulainen, Tatu Samuli;

Book Chapters

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Circularly Polarized Luminescence from Intramolecular ExcimersZinna, Francesco; Brun, Elodie; Homberg, Alexandre; Lacour, Jérôme;

2019

Scientific Articles

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In My Element: SulfurMatile, Stefan;
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A Chalcogen-Bonding Cascade Switch for Planarizable Push-Pull ProbesMacchione, Mariano; Goujon, Antoine; Strakova, Karolina; Humeniuk, Heorhii; ... Matile, Stefan
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Anion Transport with Pnictogen Bonds in Direct Comparison with Chalcogen and Halogen BondsLee, Lucia M.; Tsemperouli, Maria; Poblador Bahamonde, Amalia Isabel; Benz, Sebastian; ... Matile, Stefan
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Anion-π Catalysis on Carbon NanotubesBornhof, Anna-Bea; Vázquez-Nakagawa, Mikiko; Rodríguez-Pérez, Laura; Ángeles Herranz, María; ... Lopez Andarias, Javier
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Black Lipid Membranes: Challenges in Simultaneous Quantitative Characterization by Electrophysiology and Fluorescence MicroscopyTsemperouli, Maria; Amstad, Esther; Sakai, Naomi; Matile, Stefan; Sugihara, Kaori
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Cell-Penetrating Dynamic-Covalent Benzopolysulfane NetworksCheng, Yangyang; Zong, Lili; Lopez Andarias, Javier; Bartolami, Eline; ... Matile, Stefan
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Cellular Uptake Mediated by Cyclic OligochalcogenidesMartinent, Rémi; Laurent, Quentin François Antoine; Sakai, Naomi; Matile, Stefan;
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Circularly-Polarized Electrochemiluminescence from a Chiral Bispyrene Organic MacrocycleZinna, Francesco; Voci, Silvia; Arrico, Lorenzo; Brun, Elodie; ... Di Bari, Lorenzo
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Configurational Lability of Imino-Substituted Ethano Tröger Bases. Insight on the Racemization MechanismBosmani, Alessandro; Guarnieri Ibanez, Alejandro José; Lacour, Jérôme;
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Coupling of DNA Circuit and Templated Reactions for Quadratic Amplification and Release of Functional MoleculesKim, Kitae; Angerani, Simona; Chang, Dalu; Winssinger, Nicolas;
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Diselenolane‐Mediated Cellular Uptake: Efficient Cytosolic Delivery of Probes, Peptides, Proteins, Artificial Metalloenzymes and Protein‐Coated Quantum DotsBartolami, Eline; Basagiannis, Dimitris; Zong, Lili; Martinent, Rémi; ... Matile, Stefan
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Dithienothiophenes at Work: Access to Mechanosensitive Fluorescent Probes, Chalcogen-Bonding Catalysis, and BeyondStrakova, Karolina; Assies, Léa; Goujon, Antoine; Piazzolla, Francesca; ... Matile, Stefan
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Fluorescent Flipper Probes: Comprehensive Twist CoverageStrakova, Karolina; Poblador Bahamonde, Amalia Isabel; Sakai, Naomi; Matile, Stefan;
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Ion-Mobility Mass Spectrometry for the Rapid Determination of the Topology of Interlocked and Knotted MoleculesKruve, Anneli; Caprice, Kenji; Lavendomme, Roy; Wollschläger, Jan M.; ... Schalley, Christoph A.
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Luciferase-Induced Photouncaging: BioluminolysisChang, Dalu; Lindberg, Eric; Feng, Suihan; Angerani, Simona; ... Winssinger, Nicolas
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Lysosome-targeted photoactivation reveals local sphingosine metabolism signaturesFeng, Suihan; Harayama, Takeshi; Chang, Dalu; Hannich, Joerg Thomas; ... Riezman, Howard
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Mechanosensitive Fluorescent Probes to Image Membrane Tension in Mitochondria, Endoplasmic Reticulum, and LysosomesGoujon, Antoine; Colom Diego, Adai; Strakova, Karolina; Mercier, Vincent; ... Matile, Stefan
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Microwave‐Assisted Synthesis and Transformations of Cationic CpRu(II)(naphthalene) and CpRu(II)(naphthoquinone) ComplexesBocekova, Eva; Epik, Bugra; Chou, Jingyu; Akiyama, Katsuhiro; ... Kundig, Ernst Peter
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Ni-Catalyzed Enantioselective Intermolecular Hydroamination of Branched 1,3-Dienes Using Primary Aliphatic AminesTran, Gaël; Shao, Wen; Mazet, Clement;
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Ni-Catalyzed Regioselective Hydroalkoxylation of Branched 1,3-DienesTran, Gaël; Mazet, Clement;
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One-Step Synthesis of Diaza Macrocycles by Rh(II)-Catalyzed [3 + 6 + 3 + 6] Condensations of Morpholines and α-Diazo-β-ketoestersHomberg, Alexandre; Poggiali, Daniele; Vishe, Mahesh; Besnard, Céline; ... Lacour, Jérôme
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Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeuticsSaarbach, Jacques; Sabale, Pramod Madhavrao; Winssinger, Nicolas;
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Remote Functionalization of α,β-Unsaturated Carbonyls by Multimetallic Sequential CatalysisRomano, Ciro; Fiorito, Daniele; Mazet, Clement;
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Single-Molecule Kinetics of Growth and Degradation of Cell-Penetrating Poly(disulfide)sPulcu, Gökçe Su; Galenkamp, Nicole Stéphanie; Qing, Yujia; Gasparini, Giulio; ... Bayley, Hagan
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Sphingolipids and membrane targets for therapeuticsLoewith, Robbie Joséph; Riezman, Howard; Winssinger, Nicolas;
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Stereochemical significance of O to N atom interchanges within cationic helicenes: experimental and computational evidence of near racemization to remarkable enantiospecificityLabrador Beltran, Maria Géraldine; Besnard, Céline; Buergi, Thomas; Poblador Bahamonde, Amalia Isabel; ... Lacour, Jérôme
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Stereoselective deconjugation of macrocyclic α,β-unsaturated esters by sequential amidation and olefin transposition: application to enantioselective phase transfer catalysisHomberg, Alexandre; Hrdina, Radim; Vishe, Mahesh; Guenee, Laure; Lacour, Jérôme
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Streptavidin interfacing as a general strategy to localize fluorescent membrane tension probes in cellsGoujon, Antoine; Strakova, Karolina; Sakai, Naomi; Matile, Stefan;
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Synchronized On/Off Switching of Four Binding Sites for Water in a Molecular Solomon LinkCaprice, Kenji; Pupier, Marion; Bauzá, Antonio; Frontera, Antonio; Cougnon, Fabien
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The Opening of 1,2-Dithiolanes and 1,2-Diselenolanes: Regioselectivity, Rearrangements, and Consequences for Poly(disulfide)s, Cellular Uptake and Pyruvate Dehydrogenase ComplexesLaurent, Quentin François Antoine; Sakai, Naomi; Matile, Stefan;
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The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product researchMcAlpine, James B.; Pauli, Guido F.; Jeannerat, Damien;
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TORC2 controls endocytosis through plasma membrane tensionRiggi, Margot; Bourgoint, Clelia; Macchione, Mariano; Matile, Stefan; ... Roux, Aurélien
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Tuning symmetry breaking charge separation in perylene bichromophores by conformational controlAster, Alexander; Licari, Giuseppe Léonardo; Zinna, Francesco; Brun, Elodie; ... Vauthey, Eric
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Turn On of a Ruthenium(II) Photocatalyst by DNA-Templated LigationAnzola, Marcello; Winssinger, Nicolas;
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Ultrafast broadband circular dichroism in the deep ultravioletOppermann, Malte; Bauer, Benjamin; Rossi, Thomas; Zinna, Francesco; ... Chergui, Majed
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Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical BiologyAngerani, Simona; Winssinger, Nicolas;

Doctoral Thesis

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Alkenes and 1,3-dienes as platforms for selective transition metal catalysisFiorito, Daniele;
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Chemoproteomics-enabled development of novel cysteine and serine reactive small molecules: from target identification to inhibitor discoveryWang, Chao;
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Complementarity of decoupling elements with respect to spectral quality in 2D pure-shift homonuclear experimentsBrucka, Marta;
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Discovery of targets of cysteine-reactive natural productsHoch, Dominic Gregor;
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Nitrogen ylide formation and subsequent reactions via Cp-Ruthenium catalyzed diazo decompositionBultel, Joël Ruben;
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Peptide nucleic acids: synthesis, cellular uptake, encoding and templated reactionSaarbach, Jacques;
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Synthesis of novel heterocycles and macrocycles via Rh(II)-catalyzed decomposition of N-Sulfonyl-1,2,3-triazolesGuarnieri Ibanez, Alejandro José;
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Synthesis, mechanism and applications of azido functionalized and α-imino carbene derived Tröger BasesBosmani, Alessandro;
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Top resolution in 2D NMR experiments combining chemical shift encoded aliased spectra and spectral reconstructionSistare Guardiola, Eduard;

2018

Scientific Articles

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A cell-penetrating artificial metalloenzyme regulates a gene switch in a designer mammalian cellOkamoto, Yasunori; Kojima, Ryosuke; Schwizer, Fabian; Bartolami, Eline; ... Ward, Thomas R.
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A fluorescent membrane tension probeColom Diego, Adai; Derivery, Emmanuel; Soleimanpour, Saeideh; Tomba, Caterina; ... Roux, Aurélien
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A General Nickel-Catalyzed Kumada Vinylation for the Preparation of 2-Substituted 1,3-DienesFiorito, Daniele; Folliet, Sarah; Liu, Yangbin; Mazet, Clement;
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A Strategy to Synthesize Molecular Knots and Links Using the Hydrophobic EffectCougnon, Fabien; Caprice, Kenji; Pupier, Marion; Bauzá, Antonio; Frontera, Antonio
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Accelerating Turnover Frequency in Nucleic Acid Templated ReactionsChang, Dalu; Kim, Kitae; Lindberg, Eric; Winssinger, Nicolas;
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Anion-π Catalysis: Focus on Nonadjacent StereocentersZhang, Xiang; Liu, Le; Lopez Andarias, Javier; Wang, Chao; ... Matile, Stefan
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Biography of Professor Nicolaou: a journey to the extremes of molecular complexityWinssinger, Nicolas;
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Bioorthogonal ChemistryWinssinger, Nicolas;
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C-Functionalized Cationic Diazaoxatriangulenes: Late-Stage Synthesis and Tuning of Physicochemical PropertiesHernandez Delgado, Irene; Pascal, Simon; Besnard, Céline; Voci, Silvia; ... Lacour, Jérôme
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Catalysis with Pnictogen, Chalcogen, and Halogen BondsBenz, Sebastian; Poblador Bahamonde, Amalia Isabel; Low-Der's, Nicolas Vinh Tri; Matile, Stefan;
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Chalcogen-Bonding Catalysis: From Neutral to Cationic Benzodiselenazole ScaffoldsBenz, Sebastian; Besnard, Céline; Matile, Stefan;
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Chimeric Streptavidins as Host Proteins for Artificial MetalloenzymesPellizzoni, Michela M.; Schwizer, Fabian; Wood, Christopher W.; Sabatino, Valerio; ... Ward, Thomas R.
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Combined reversible switching of ECD and quenching of CPL with chiral fluorescent macrocyclesHomberg, Alexandre; Brun, Elodie; Zinna, Francesco; Pascal, Simon; ... Lacour, Jérôme
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Conjugated Polyimine Dynamers as Phase-Sensitive Membrane ProbesSakai, Naomi; Matile, Stefan;
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Copper-catalyzed enantioselective 1,2-borylation of 1,3-dienesLiu, Yangbin; Fiorito, Daniele; Mazet, Clement;
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Cysteine-reactive probes and their use in chemical proteomicsHoch, Dominic Gregor; Abegg, Daniel; Adibekian, Alexander;
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Decrease in plasma membrane tension triggers PtdIns(4,5)P2 phase separation to inactivate TORC2Riggi, Margot; Niewola-Staszkowska, Karolina; Chiaruttini, Nicolas; Colom Diego, Adai; ... Loewith, Robbie Joséph
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Detecting order and lateral pressure at biomimetic interfaces using a mechanosensitive second-harmonic-generation probeLicari, Giuseppe Léonardo; Beckwith, Joseph; Soleimanpour, Saeideh; Matile, Stefan; Vauthey, Eric
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Diselenolane-mediated cellular uptakeChuard, Nicolas; Poblador Bahamonde, Amalia Isabel; Zong, Lili; Bartolami, Eline; ... Matile, Stefan
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Double-Stranded RNA-Specific Templated Reaction with Triplex Forming PNAKim, Kitae; Chang, Dalu; Winssinger, Nicolas;
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Editorial overview: Synthetic biomoleculesPayne, Richard J.; Winssinger, Nicolas;
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Efficient Synthesis of Ditopic Polyamide Receptors for Cooperative Ion Pair Recognition in Solution and Solid StatesRay, Sumit Kumar; Homberg, Alexandre; Vishe, Mahesh; Besnard, Céline; Lacour, Jérôme
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Excimer-Based On-Off Bis(pyreneamide) Macrocyclic ChemosensorsVishe, Mahesh; Lathion, Timothee; Pascal, Simon; Yushchenko, Oleksandr; ... Lacour, Jérôme
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Exploring the mechanism of the Pd-catalyzed spirocyclization reaction: a combined DFT and experimental studyFranzoni, Ivan; Yoon, Hyung; García-López, José-Antonio; Poblador Bahamonde, Amalia Isabel; Lautens, Mark
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Ganglioside-Selective Mechanosensitive Fluorescent Membrane ProbesStrakova, Karolina; Soleimanpour, Saeideh; Diez Castellnou, Marta; Sakai, Naomi; Matile, Stefan
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