Département de chimie organique

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2021

Scientific Articles

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Biosupramolecular Systems: Integrating Cues into ResponsesWatson, Emma; Angerani, Simona; Sabale, Pramod Madhavrao; Winssinger, Nicolas;
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Bright Long‐Lived Circularly Polarized Luminescence in Chiral Chromium(III) ComplexesJimenez, Juan; Poncet, Maxime Arnaud; Míguez‐Lago, Sandra; Grass, Stéphane; ... Piguet, Claude
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Chiral Near‐Infrared Fluorophores by Self‐Promoted Oxidative Coupling of Cationic Helicenes with Amines/EnaminesBosson, Johann; Labrador Beltran, Maria Géraldine; Besnard, Céline; Jacquemin, Denis; Lacour, Jérôme
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Combined spectroscopic studies on post-functionalized Au25 cluster as an ATR-FTIR sensor for cationsBaghdasaryan, Ani; Brun, Elodie; Wang, Yuming; Salassa, Giovanni; ... Buergi, Thomas
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Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2Farrera Soler, Lluc; Daguer, Jean Pierre; Barluenga Badiola, Sofia; Winssinger, Nicolas;
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Fluorescent Membrane Tension Probes for Early EndosomesPiazzolla, Francesca; Mercier, Vincent; Assies, Léa; Sakai, Naomi; ... Matile, Stefan
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Genetically Encoded Supramolecular Targeting of Fluorescent Membrane Tension Probes within Live Cells: Precisely Localized Controlled Release by External Chemical StimulationLopez Andarias, Javier; Strakova, Karolina; Martinent, Rémi; Jimenez Rojo, Noemi; ... Matile, Stefan
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High Sensitivity Detection of a Solubility Limiting Surface Transformation of Drug Particles by DNP SENSViger-Gravel, Jasmine; Pinon, Arthur C.; Björgvinsdóttir, Snædís; Skantze, Urban; ... Emsley, Lyndon
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Hybrids of cationic [4]helicene and N-heterocyclic carbene as ligands for complexes exhibiting (chir)optical properties in the far red spectral windowTarrieu, Robert; Hernandez Delgado, Irène; Zinna, Francesco; Dorcet, Vincent; ... Lacour, Jérôme
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Inhibitors of thiol-mediated uptakeCheng, Yangyang; Pham, Anh Tuan; Kato, Takehiro; Lim, Bumhee; ... Matile, Stefan
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Kinesin-1 activity recorded in living cells with a precipitating dyeAngerani, Simona; Lindberg, Eric; Klena, Nikolai; Bleck, Christopher K. E.; ... Winssinger, Nicolas
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Lifetime Broadening and Impulsive Generation of Vibrational Coherence Triggered by Ultrafast Electron TransferAster, Alexander; Bornhof, Anna-Bea; Sakai, Naomi; Matile, Stefan; Vauthey, Eric
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Long-lived triplet charge-separated state in naphthalenediimide based donor–acceptor systemsAster, Alexander; Rumble, Christopher Allen; Bornhof, Anna-Bea; Huang, Hsin-Hua; ... Vauthey, Eric
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Luciferase Controlled Protein InteractionsChang, Dalu; Feng, Suihan; Girik, Vladimir; Riezman, Howard; Winssinger, Nicolas
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Mitochondrial membrane tension governs fissionMahecic, Dora; Carlini, Lina; Kleele, Tatjana; Colom Diego, Adai; ... Manley, Suliana
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Oligomers of Cyclic Oligochalcogenides for Enhanced Cellular UptakeMartinent, Rémi; Du, Dongchen; Lopez Andarias, Javier; Sakai, Naomi; Matile, Stefan
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Organic Chemistry for First Year Medical Students: Addressing the 'Grand Public'Matile, Stefan;
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Regiodivergent synthesis of pyrazino-indolines vs. triazocines via α-imino carbenes addition to imidazolidinesGuarnieri Ibanez, Alejandro José; de Aguirre, Adiran; Besnard, Céline; Poblador Bahamonde, Amalia Isabel; Lacour, Jérôme
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Rh(II)-Catalyzed Condensations of N-Sulfonyl-1,2,3-triazoles with AminalsSaleh, Nidal; Lacour, Jérôme;
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Role of Intercluster and Interligand Dynamics of [Ag25(DMBT)18] Nanoclusters by Multinuclear Magnetic Resonance SpectroscopySalassa, Giovanni; Krishnadas, Kumaranchira Ramankutty; Pupier, Marion; Viger-Gravel, Jasmine; Buergi, Thomas
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Singlet Fission in a Flexible Bichromophore with Structural and Dynamic ControlAster, Alexander; Zinna, Francesco; Rumble, Christopher Allen; Lacour, Jérôme; Vauthey, Eric
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The Nuclear Transport Protein Importin-5: A Promising Target in Oncology and VirologyPatouret, Rémi;
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The primary dipole of flipper probesGARCIA, José; Lopez Andarias, Javier; Sakai, Naomi; Matile, Stefan;
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Total Syntheses of Paraconic Acids and 1,10-seco-Guaianolides via a Barbier Allylation/Translactonization Cascade of 3-(Bromomethyl)-2(5H)-furanoneLiu, Weilong; Yu, Zhimei; Winssinger, Nicolas;
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Transition metal-catalyzed alkene isomerization as an enabling technology in tandem, sequential and domino processesFiorito, Daniele; Scaringi, Simone; Mazet, Clement;
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Two-step immobilization of metronidazole prodrug on TEMPO cellulose nanofibrils through thiol-yne click chemistry for in situ controlled releaseDurand, Hippolyte; Baussanne, Isabelle; Demeunynck, Martine; Viger-Gravel, Jasmine; ... Bras, Julien

Book Chapters

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Anion Transport in Lipid Bilayer Membranes Using Halogen BondsVargas Jentzsch, Rodrigo Andreas; Matile, Stefan;

2020

Scientific Articles

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A Catalytic Dual Isomerization/Allylboration Sequence for the Stereoselective Construction of Congested Secondary Homoallylic AlcoholsLiu, Yangbin; Mazet, Clement;
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Access to Chiral Rigid Hemicyanine Fluorophores from Tröger Bases and α-Imino CarbenesSaleh, Nidal; Bosmani, Alessandro; Besnard, Céline; Buergi, Thomas; ... Lacour, Jérôme
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Access to Optically Active 7-Membered Rings by a 2-Step Synthetic Sequence: Cu-Catalyzed Stereoselective Cyclopropanation of Branched 1,3-Dienes/Rh-Catalyzed Stereoconvergent [5 + 2] CycloadditionGarbo, Michele; Besnard, Céline; Guenee, Laure; Mazet, Clement;
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Automated high-content imaging for cellular uptake, from the Schmuck cation to the latest cyclic oligochalcogenidesMartinent, Rémi; Lopez Andarias, Javier; Moreau, Dimitri; Cheng, Yangyang; ... Matile, Stefan
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Caprin‐1 Promotes Cellular Uptake of Nucleic Acids with Backbone and Sequence DiscriminationGalli, Valentina; Sadhu, Kalyan Kumar; Masi, Daniela; Saarbach, Jacques; ... Winssinger, Nicolas
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Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane NetworksLopez Andarias, Javier; Saarbach, Jacques; Moreau, Dimitri; Cheng, Yangyang; ... Matile, Stefan
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Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9Plank, Michaël; Perepelkina, Mariya; Muller, Markus Johann; Vaga, Stefania; ... Loewith, Robbie Joséph
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Chiroptical detection of a model ruthenium dye in water by circularly polarized-electrochemiluminescenceVoci, Silvia; Zinna, Francesco; Arrico, Lorenzo; Grass, Stéphane; ... Sojic, Neso
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Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory PathwayJimenez Rojo, Noemi; Leonetti, Manuel D.; Zoni, Valeria; Colom Diego, Adai; ... Riezman, Howard
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Direct Access to Chiral Secondary Amides by Copper-Catalyzed Borylative Carboxamidation of Vinylarenes with IsocyanatesFiorito, Daniele; Liu, Yangbin; Besnard, Céline; Mazet, Clement;
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EditorialKundig, Ernst Peter;
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Empowering Global Chemical Biology at the Dawn of the New DecadeHoogendoorn, Sascha; Aye, Yimon;
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Enantiopure encaged Verkade's superbases: Synthesis, chiroptical properties, and use as chiral derivatizing agentYang, Jian; Chatelet, Bastien; Hérault, Damien; Dufaud, Véronique; ... Martinez, Alexandre
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Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formationMercier, Vincent; Larios, Jorge; Molinard, Guillaume; Goujon, Antoine; ... Roux, Aurélien
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Enhanced SNP-sensing using DNA-templated reactions through confined hybridization of minimal substrates (CHOMS)Kim, Kitae; Winssinger, Nicolas;
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Everything you wanted to know about phase and reference frequency in one- and two-dimensional NMR spectroscopySheberstov, Kirill; Sistare Guardiola, Eduard; Jeannerat, Damien;
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Fluorescent Membrane Tension Probes for Super-Resolution Microscopy: Combining Mechanosensitive Cascade Switching with Dynamic-Covalent Ketone ChemistryGARCIA, José; Maillard, Jimmy Stéphane; Fureraj, Ina; Strakova, Karolina; ... Matile, Stefan
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Fluorescent small-molecule agonists as follicle-stimulating hormone receptor imaging toolsHoogendoorn, Sascha; van Puijvelde, Gijs H. M.; van der Marel, Gijs A.; van Koppen, Chris J.; ... Overkleeft, Herman S.
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From Phenotypic Hit to Chemical Probe: Chemical Biology Approaches to Elucidate Small Molecule Action in Complex Biological SystemsPasquer, Quentin; Tsakoumagkos, Ioannis; Hoogendoorn, Sascha;
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From reactive carbenes to chiral polyether macrocycles in two steps – synthesis and applications made easy?Homberg, Alexandre; Lacour, Jérôme;
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HaloFlippers: a General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living CellsStrakova, Karolina; Lopez Andarias, Javier; Jimenez Rojo, Noemi; Chambers, Joseph E.; ... Matile, Stefan
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High-speed atomic force microscopy highlights new molecular mechanism of daptomycin actionZuttion, Francesca; Colom Diego, Adai; Matile, Stefan; Farago, Denes; ... Casuso, Ignacio
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Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasmaFarrera Soler, Lluc; Daguer, Jean Pierre; Barluenga Badiola, Sofia; Vadas, Oscar; ... Winssinger, Nicolas
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Kilian Muñiz (1970–2020)Streuff, Jan; Echavarren, Antonio M.; González, José Manuel; Oestreich, Martin; ... Winssinger, Nicolas
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Ligand exchange reactions on the chiral Au38 cluster: CD modulation caused by the modification of the ligand shell compositionBaghdasaryan, Ani; Martin, Kévin; Lawson Daku, Latevi Max; MastropasquaTalamo, Maurizio; ... Buergi, Thomas
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Mapping Cell Membrane Organization and Dynamics Using Soft Nanoimprint LithographySansen, T.; Sanchez-Fuentes, D.; Rathar, R.; Colom Diego, Adai; ... Picas, L.
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Mechanosensitive Fluorescent Probes, Changing Color Like Lobsters during Cooking: Cascade Switching VariationsKato, Takehiro; Strakova, Karolina; Garcia, José; Sakai, Naomi; Matile, Stefan
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Mechanosensitive membrane probes: push-pull papillonsHumeniuk, Heorhii; Licari, Giuseppe Léonardo; Vauthey, Eric; Sakai, Naomi; Matile, Stefan
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Merging polyacenes and cationic helicenes: from weak to intense chiroptical properties in the far red regionDuwald, Romain; Bosson, Johann; Pascal, Simon; Grass, Stéphane; ... Lacour, Jérôme
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Methyl Scanning for Mechanochemical Chalcogen‐Bonding Cascade SwitchesZhang, Xiang; Sakai, Naomi; Matile, Stefan;
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Naphthalenediimides with Cyclic Oligochalcogenides in Their CoreShybeka, Inga; Aster, Alexander; Cheng, Yangyang; Sakai, Naomi; ... Matile, Stefan
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Near-infrared electrochemiluminescence in water through regioselective sulfonation of diaza [4] and [6]helicene dyesLi, Haidong; Duwald, Romain; Pascal, Simon; Voci, Silvia; ... Sojic, Neso
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Ni-Catalyzed Regiodivergent and Stereoselective Hydroalkylation of Acyclic Branched Dienes with Unstabilized C(sp3) NucleophilesShao, Wen; Besnard, Céline; Guenee, Laure; Mazet, Clement;
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Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion couplingOberhauser, Lucie; Granziera, Sabrina; Colom Diego, Adai; Goujon, Antoine; ... Maechler, Pierre
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Peptide Stapling with Anion‐π CatalystsPham, Anh Tuan; Matile, Stefan;
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Photo-induced thiol–ene reactions for late-stage functionalization of unsaturated polyether macrocycles: regio and diastereoselective access to macrocyclic dithiol derivativesBrun, Elodie; Zhang, Kefeng; Guenee, Laure; Lacour, Jérôme;
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PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectinsFarrera Soler, Lluc; Daguer, Jean Pierre; Raunft, PATRICK; Barluenga Badiola, Sofia; ... Winssinger, Nicolas
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Pnictogen-bonding catalysis: brevetoxin-type polyether cyclizationsGini, Andrea; Paraja, Miguel; Galmés, Bartomeu; Besnard, Céline; ... Matile, Stefan
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Pnictogen‐Bonding Catalysis: An Interactive Tool to Uncover Unorthodox Mechanisms in Polyether Cascade CyclizationsParaja, Miguel; Gini, Andrea; Sakai, Naomi; Matile, Stefan;
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Polyether Natural Product Inspired Cascade Cyclizations: Autocatalysis on π‐Acidic Aromatic SurfacesParaja, Miguel; Hao, Xiaoyu; Matile, Stefan;
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Preparation and Structural Characterization of [CpRu(1,10‐phenanthroline)(CH3CN)][X] and Precursor Complexes (X=PF6, BArF, TRISPHAT‐N)Achard, Thierry; Egger, Léo; Tortoreto, Cecilia; Guenee, Laure; Lacour, Jérôme
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Primary Anion–π Catalysis of Epoxide‐Opening Ether Cyclization into Rings of Different Sizes: Access to New ReactivityParaja, Miguel; Matile, Stefan;
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Probing for Thiol-Mediated Uptake into BacteriaLaurent, Quentin François Antoine; Berthet, Mathéo; Cheng, Yangyang; Sakai, Naomi; ... Matile, Stefan
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SAN plot: A graphical representation of the signal, noise, and artifacts content of spectraSheberstov, Kirill F.; Sistare Guardiola, Eduard; Pupier, Marion; Jeannerat, Damien;
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Self-enhanced multicolor electrochemiluminescence by competitive electron-transfer processesVoci, Silvia; Duwald, Romain; Grass, Stéphane; Hayne, David J.; ... Sojic, Neso
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Sense-and-Release Logic-Gated Molecular Network Responding to Dimeric Cell Surface ProteinsAngerani, Simona; Winssinger, Nicolas;
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Small Molecules Targeting the Hedgehog Pathway: From Phenotype to Mechanistic UnderstandingHoogendoorn, Sascha;
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Small-molecule modulators of the ATPase VCP/p97 affect specific p97 cellular functionsFiguerola Conchas, Ainoa; Saarbach, Jacques; Daguer, Jean Pierre; Cieren, Adeline; ... Gotta, Monica
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Smartphone DNA or RNA Sensing Using Semisynthetic Luciferase-Based Logic DeviceChang, Dalu; Kim, Kitae; Lindberg, Eric; Winssinger, Nicolas;
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Synthesis and properties of chiral fluorescent helicene-BODIPY conjugatesMoneva Lorente, Pau; Wallabregue, Antoine; Zinna, Francesco; Besnard, Céline; ... Lacour, Jérôme
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Synthesis, characterization, catalytic and biological application of half-sandwich ruthenium complexes bearing hemilabile (κ2-C,S)-thioether-functionalised NHC ligandsChen, Weiguang; Egly, Julien; Poblador Bahamonde, Amalia Isabel; Maisse-Francois, Aline; ... Achard, Thierry
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Synthesis, Resolution, Configurational Stability, and Properties of Cationic Functionalized [5]HelicenesMarinova, Maya Krasimirova; Pascal, Simon; Guenee, Laure; Besnard, Céline; ... Lacour, Jérôme
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Tateshina: Swiss Inspiration!Kundig, Ernst Peter;
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The RB596 antibody recognizes a linear epitope from the spike S protein from SARS-CoV-2Farrera Soler, Lluc; Daguer, Jean Pierre; Barluenga Badiola, Sofia; Winssinger, Nicolas;
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The Structure of Molecular and Surface Platinum Sites Determined by DNP-SENS and Fast MAS 195Pt Solid-State NMR SpectroscopyVenkatesh, Amrit; Lund, Alicia; Rochlitz, Lukas; Jabbour, Ribal; ... Rossini, Aaron J.
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Twisting and tilting of a mechanosensitive molecular probe detects order in membranesLicari, Giuseppe Léonardo; Strakova, Karolina; Matile, Stefan; Tajkhorshid, Emad;
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Untying the Photophysics of Quinolinium‐Based Molecular Knots and LinksCaprice, Kenji; Aster, Alexander; Cougnon, Fabien; Kumpulainen, Tatu Samuli;
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[n]Dendralenes as a Platform for Selective Catalysis: Ligand-Controlled Cu-Catalyzed Chemo-, Regio-, and Enantioselective BorylationsDesfeux, Camille Marie Odette; Besnard, Céline; Mazet, Clement;

Book Chapters

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Circularly Polarized Luminescence from Intramolecular ExcimersZinna, Francesco; Brun, Elodie; Homberg, Alexandre; Lacour, Jérôme;
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PNA-Encoded Synthesis (PES) and DNA Display of Small Molecule LibrariesSaarbach, Jacques; Barluenga Badiola, Sofia; Winssinger, Nicolas;

Doctoral Thesis

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Anion-pi Catalysis: Foldamers, Carbon Nanotubes and Electric FieldsBornhof, Anna-Bea;
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Mechanosensitive fluorescent probes for practical use in biology: towards more sensitive and precisely localized membrane tension reportersStrakova, Karolina;
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Sequence-Specific DNA/RNA Detection and Photouncaging in Chemical BiologyChang, Dalu;
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Synthesis and conformational study of imine- and hydrazone-based [2]catenanesCaprice, Kenji;
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Synthesis and Late-Stage Functionalization of pH-Sensitive Quinacridine and Diazaoxatriangulene FluorophoresMoneva Lorente, Pau;
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