Section de médecine fondamentale

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2021

Scientific Articles

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A cytotoxic porphyrin from North Pacific brittle star Ophiura sarsiiKlimenko, Antonina; Huber, Robin; Marcourt, Laurence; Chardonnens, Estelle; ... Katanaev, Vladimir
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A mutual information-based in vivo monitoring of adaptive response to targeted therapies in melanomaBugi, Aurore; Noulet, Fanny; Liaudet, Nicolas; Merat, Rastine;
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A rationally designed oral vaccine induces immunoglobulin a in the murine gut that directs the evolution of attenuated salmonella variantsDiard, Médéric; Bakkeren, Erik; Lentsch, Verena; Rocker, Andrea; ... Slack, Emma
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ABCB4 variants in adult patients with cholestatic disease are frequent and underdiagnosedAvena, Antonella; Puggelli, Sandro; Morris, Michael; Cerny, Andreas; ... Terziroli Beretta-Piccoli, Benedetta
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Accoutumance à la morphine : probiotiques à la rescousseEl Matribi, Zacharie Elie; Gözlügöl, Ezgi; Lazzarotto, Célia Sophie Bernadette; Ollivier, Julien; ... Laumonier, Thomas
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Amino acid metabolism in apicomplexan parasitesKrishnan, Aarti; Soldati-Favre, Dominique;
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An organelle-tethering mechanism couples flagellation to cell division in bacteriaSiwach, Manisha; Kumar, Lokesh; Palani, Saravanan; Muraleedharan, Samada; ... Radhakrishnan, Sunish Kumar
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BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortexBraun, Simon; Petrova, Ralitsa; Tang, Jiong; Krokhotin, Andrey; ... Crabtree, Gerald R.
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Browning of white adipose tissue as a therapeutic tool in the fight against atherosclerosisRoth, Christel; Molica, Filippo; Kwak, Brenda;
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Bugs R Us: restoring sociability with microbiota in autismBellone, Camilla; Luscher, Christian;
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Calcium signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKGBalestra, Aurélia; Koussis, Konstantinos; Klages Jemelin, Natacha; Howell, Steven A.; ... Brochet, Mathieu
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Cell heterogeneity and paracrine interactions in human islet function: a perspective focused in β-cell regeneration strategiesBru Tari, Eva Maria; Oropeza, Daniel; Herrera, Pedro Luis;
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Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocksSinturel, Flore; Gos, Pascal; Petrenko, Volodymyr; Hagedorn, Claudia; ... Schibler, Ueli
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CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cellsRoy, Sougata; Sipthorp, James; Mahata, Bidesh; Pramanik, Jhuma; ... Teichmann, Sarah A.
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Clinical presentation and gene expression of acute alcohol-induced microvesicular steatosis mimicking alcoholic hepatitisSpahr, Laurent François Joséph; Lanthier, Nicolas; Tihy, Matthieu; Frossard, Jean-Louis; ... Goossens, Nicolas
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Clinical, virological and immunological features of a mild case of SARS-CoV-2 re-infectionVetter, Pauline; Cordey, Samuel; Schibler, Manuel; Vieux, Laure; ... Kaiser, Laurent
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Co-translational assembly and localized translation of nucleoporins in nuclear pore complex biogenesisLautier, Ophélie; Penzo, Arianna; Rouvière, Jérôme O; Chevreux, Guillaume; ... Palancade, Benoit
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Comparison of different activators of coagulation by turbidity analysis of hereditary dysfibrinogenemia and controlsMarchi Cappelletti, Rita; Neerman Arbez, Marguerite; Gay, Valérie; Mourey, Guillaume; ... Casini, Alessandro
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Consolidating the circuit model for addictionLuscher, Christian; Janak, Patricia H;
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COVID‐19 encephalopathy: Clinical and neurobiological featuresUginet, Marjolaine; Breville, Gautier; Assal, Frédéric; Lövblad, Karl-Olof; ... Allali, Gilles
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Detecting early myocardial ischemia in rat heart by MALDI imaging mass spectrometryAljakna Khan, Aleksandra; Bararpour, Nasim; Gorka, Marie; Joye, Timothée; ... Sabatasso, Sara
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Diagnostic accuracy of two commercial SARS-CoV-2 antigen-detecting rapid tests at the point of care in community-based testing centersBerger, Alice; Ngo Nsoga, Marie Thérèse; Perez Rodriguez, Francisco Javier; Abi Aad, Yasmine; ... Eckerle, Isabella Anne
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Dietary sodium intake does not alter renal potassium handling and blood pressure in healthy young malesPechere, Antoinette; Olivier, Valérie; Burnier, Michel; Udwan, Khalil; ... Feraille, Eric
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Differential role of nicotinamide adenine dinucleotide deficiency in acute and chronic kidney diseaseFaivre, Anna; Katsyuba, Elena; Verissimo, Thomas; Lindenmeyer, Maja; ... De Seigneux Matthey, Sophie
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Dysfunctional keratinocytes increase dermal inflammation in systemic sclerosis. Results from tissue-engineered scleroderma epidermisRusso, Barbara; Borowczyk, Julia; Boehncke, Wolf-Henning; Truchetet, Marie-Elise; ... Chizzolini, Carlo
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Dysmaturation Observed as Altered Hippocampal Functional Connectivity at Rest Is Associated With the Emergence of Positive Psychotic Symptoms in Patients With 22q11 Deletion SyndromeDelavari, Farnaz; Sandini, Corrado; Zoeller, Daniela; Mancini, Valentina; ... Eliez, Stéphan
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Editorial: memory T cells in chronic infections and tumorsHofmann, Maike; Jandus, Camilla; Lee, Lian Ni; Utzschneider, Daniel T;
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Effect of 5-HT2A receptor antagonism on levels of D2/3 receptor occupancy and adverse behavioral side-effects induced by haloperidol: a SPECT imaging study in the ratTsartsalis, Stergios; Tournier, Benjamin; Gloria, Yesica; Millet, Philippe; Ginovart, Nathalie
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eIF4E3 forms an active eIF4F complex during stresses (eIF4FS) targeting mTOR and re-programs the translatomeWeiss, Benjamin; Allen, George Edward; Kloehn, Joachim; Abid, Karim; ... Curran, Joseph
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Episodic future thinking in autism spectrum disorder and 22q11.2 deletion syndrome: association with anticipatory pleasure and social functioningFeller, Clémence; Dubois, Charlotte; Eliez, Stéphan; Schneider, Maude;
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Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patientsHannich, Joerg Thomas; Loizides-Mangold, Ursula Elfriede; Sinturel, Flore; Harayama, Takeshi; ... Dibner, Charna
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Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoidBertiaux, Eloise; Balestra, Aurélia; Bournonville, Lorène; Louvel, Vincent; ... Hamel, Virginie
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Fibrin clot properties to assess the bleeding phenotype in unrelated patients with hypodysfibrinogenemia due to novel fibrinogen mutationsMarchi Cappelletti, Rita; Ferreira Vilar Da Silva, Rui Filipe; Durual, Stéphane; Goodyer, Matthew; ... Casini, Alessandro
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Formation and immunomodulatory function of meningeal B-cell aggregates in progressive CNS autoimmunityMitsdörffer, Meike; Di Liberto, Giovanni; Dötsch, Sarah; Sie, Christopher; ... Korn, Thomas
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GDF11 rapidly increases lipid accumulation in liver cancer cells through ALK5-dependent signalingFrohlich, Jan; Mazza, Tommaso; Sobolewski, Cyril; Foti, Michelangelo; Vinciguerra, Manlio
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Gestational trophoblastic disease in Switzerland: retrospective study of the impact of a regional reference centreFehlmann, Aurore; Benkortbi, Khadidja; Rosseel, Ginette; Meyer-Hamme, Ulrike; ... Undurraga Malinverno, Manuela Stefania
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Happy birthday: 30 years of RNA helicasesValentini, Martina; Linder, Patrick;
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HDV pathogenesis: unravelling ariadne's threadTseligka, Eirini; Clement, Sophie; Negro, Francesco;
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Head-to-head evaluation of five automated SARS-CoV-2 serology immunoassays in various prevalence settingsAndrey, Diego Olivier; Yerly Ferrillo, Sabine; Meyer, Benjamin; Arm-Vernez, Isabelle; ... Vuilleumier, Nicolas
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Heat-stability study of various insulin types in tropical temperature conditions: new insights towards improving diabetes careKaufmann, Béatrice; Boulle, Philippa; Berthou, Flavien; Fournier, Margot; ... Scapozza, Leonardo
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Hepatitis C prevalence in the psychiatric setting: cost-effectiveness of scaling-up screening and direct-acting antiviral therapyGirardin, François; Painter, Chris; Hearmon, Natalie; Eddowes, Lucy; ... Vernaz-Hegi, Nathalie
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Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attackBonilla, Weldy V; Kirchhammer, Nicole; Marx, Anna-Friederike; Kallert, Sandra M; ... Pinschewer, Daniel D
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IL-1 family antagonists in mouse and human skin inflammationRodriguez Martin, Praxedis Sina; Goldstein, Jérémie David; Mermoud, Loïc Xavier; Diaz Barreiro, Alejandro; Palmer-Lourenco, Gaby
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IL-38 Ablation Reduces Local Inflammation and Disease Severity in Experimental Autoimmune EncephalomyelitisHuard, Arnaud; Do, Hoai Nam; Frank, Ann-Christin; Sirait-Fischer, Evelyn; ... Weigert, Andreas
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Impact of immunotherapy on CD4 T cell phenotypes and function in cancerSaillard, Margaux; Cenerenti, Mara; Romero, Pedro; Jandus, Camilla;
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Light polarization by biological nanocoatingsKryuchkov, Mikhail; Savitsky, Vladimir; Wilts, Bodo D; Gray, Elmer; Katanaev, Vladimir
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Lymphatic connexins and pannexins in health and diseaseEhrlich, Avigail; Molica, Filippo; Hautefort, Aurélie; Kwak, Brenda;
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Macroautophagy in lymphatic endothelial cells inhibits T cell-mediated autoimmunityHarle, Guillaume; Kowalski, Camille; Dubrot Armendariz, Juan; Brighouse, Dale; ... Hugues, Stéphanie
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Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cellsSeguin, Laetitia; Odouard, Soline; Corlazzoli, Francesca; Al Haddad, Sarah; ... Cosset, Erika
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MAFLD considerations as a part of the global hepatitis C elimination effort: an international perspectiveFouad, Yasser; Lazarus, Jeffrey V; Negro, Francesco; Peck-Radosavljevic, Markus; ... Colombo, Massimo
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Maladies infectieusesNguyen, Aude; Posfay Barbe, Klara; Blanchard Rohner, Géraldine; Buvelot, Hélène; ... Csaki Huttner, Angela
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Management of acute Wilsonian hepatitis with severe hemolysis: a successful combination of chelation and MARS dialysisHassoun, Jérémy; Hammer, Nathalie; Magini, Giulia; Ponte, Belen; ... Spahr, Laurent François Joséph
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MHC class II antigen presentation by lymphatic endothelial cells in tumors promotes intratumoral regulatory T cell-suppressive functionsGkountidi, Anastasia-Olga; Garnier, Laure; Dubrot Armendariz, Juan; Angelillo, Julien; ... Hugues, Stéphanie
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Molecular characterization of pathogenic OTOA gene conversions in hearing loss patientsLaurent, Sacha; Gehrig, Corinne; Nouspikel, Thierry; Amr, Sami S; ... Guipponi, Michel
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NAFLD and MAFLD as emerging causes of HCC: a populational studyMyers, Shuna; Neyroud, Isabelle; Spahr, Laurent François Joséph; Gkouvatsos, Konstantinos; ... Goossens, Nicolas
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Nanopattern surface improves cultured human myotube maturationBrunetti, Jessica; Konig, Stéphane; Monnier, Arthur; Frieden, Maud;
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Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2bChan, Li-Jin; Gandhirajan, Anugraha; Carias, Lenore L.; Dietrich, Melanie H.; ... Tham, Wai-Hong
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Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammationWoo, Marcel S; Ufer, Friederike; Rothammer, Nicola; Di Liberto, Giovanni; ... Friese, Manuel A
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Neuropathology associated with SARS-CoV-2 infectionEgervari, Kristof Levente; Thomas, Christian; Lobrinus, Johannes Alexander; Kuhlmann, Tanja; ... Merkler, Doron
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New advances in immune components mediating viral control in the CNS.Vincenti, Ilena; Merkler, Doron;
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Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulatorAllou, Lila; Andrey, Guillaume; Superti-Furga, Andrea;
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NREM sleep stages specifically alter dynamical integration of large-scale brain networksTarun, Anjali; Wainstein-Andriano, Danyal; Sterpenich, Virginie; Bayer, Laurence; ... Van De Ville, Dimitri
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Optimization of the clofazimine structure leads to a highly water-soluble C3-aminopyridinyl riminophenazine endowed with improved anti-Wnt and anti-cancer activity in vitro and in vivoKoval, Alexey; Bassanini, Ivan; xu, Jiabin; Tonelli, Michele; ... Katanaev, Vladimir
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Persistence of self-reactive CD8+ T cells in the CNS requires TOX-dependent chromatin remodelingPage, Nicolas; Lemeille, Sylvain; Vincenti, Ilena; Klimek, Bogna; ... Merkler, Doron
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PET imaging of dopamine neurotransmission during EEG neurofeedbackRos, Tomas; Kwiek, Jessica Bernadetta; Andriot, Théo; Michela, Abele; ... Ginovart, Nathalie
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Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulationJafari, Mehrnoosh; Schumacher, Adrian-Minh; Snaidero, Nicolas; Ullrich Gavilanes, Emily M; ... Kerschensteiner, Martin
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PPARɣ drives IL-33-dependent ILC2 pro-tumoral functionsErcolano, Giuseppe; Gomez Cadena, Alejandra; Dumauthioz, Nina; Vanoni, Giulia; ... Jandus, Camilla
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Primary cilia control endothelial permeability by regulating expression and location of junction proteinsDiagbouga, Mannekomba Roxane; Morel, Sandrine; Cayron, Anne France Judith; Haemmerli, Julien; ... Kwak, Brenda
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Prior reward conditioning dampens hippocampal and striatal responses during an associative memory taskMiendlarzewska, Ewa; Aberg, Carl Kristoffer; Bavelier, Daphné; Schwartz, Sophie;
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Protein phosphatase 1 regulates atypical mitotic and meiotic division in Plasmodium sexual stagesZeeshan, Mohammad; Pandey, Rajan; Subudhi, Amit Kumar; Ferguson, David J P; ... Tewari, Rita
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Psycho-social factors associated with mental resilience in the Corona lockdownVeer, Ilya M.; Riepenhausen, Antje; Zerban, Matthias; Wackerhagen, Carolin; ... Kalisch, Raffael
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Rapid transcriptional and metabolic adaptation of intestinal microbes to host immune activationBecattini, Simone; Sorbara, Matthew T.; Kim, Sohn G.; Littmann, Eric L.; ... Pamer, Eric G.
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Real-world effectiveness and safety of glecaprevir/pibrentasvir therapy in patients with chronic hepatitis C virus infection in SwitzerlandMüllhaupt, Beat; Semela, David; Ruckstuhl, Lisa; Magenta, Lorenzo; ... Semmo, Nasser
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Real-world outcomes in historically underserved patients with chronic hepatitis C infection treated with Glecaprevir/PibrentasvirAghemo, Alessio; Horsmans, Yves; Bourgeois, Stefan; Bondin, Mark; ... Lampertico, Pietro
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Recommandations pour le suivi des patients atteints d’hépatite C guérieBobzin, Carina; Bsiger, Christophe; Bruggmann, Philip; Cerny, Andreas; ... Thurnheer, Maria Christine
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Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapySiwicki, Marie; Gort-Freitas, Nicolas A; Messemaker, Marius; Bill, Ruben; ... Pittet, Mikaël
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Residual risk of liver disease after hepatitis C virus eradicationNegro, Francesco;
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RNase J1 and J2 are host-encoded factors for plasmid replicationAndrade Guimaraes, Vanessa; Le Scornet, Alexandre; Khemici, Vanessa; Hausmann, Stéphane; ... Redder, Peter
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RSV and HMPV infections in 3d tissue cultures: mechanisms involved in virus-host and virus-virus interactionsGeiser, Johan; Boivin, Guy; Huang, Song; Constant, Samuel; ... Essaidi, Manel
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Severe COVID-19 patients exhibit an ILC2 NKG2D+ population in their impaired ILC compartmentGomez Cadena, Alejandra; Spehner, Laurie; Kroemer, Marie; Khelil, Myriam Ben; ... Jandus, Camilla
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Simultaneous determination of intraluminal lysosomal calcium and pH by dextran-conjugated fluorescent dyesPihan, Philippe; Nunes-Hasler, Paula; Demaurex, Nicolas; Hetz, Claudio;
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Single-cell immune repertoire and transcriptome sequencing reveals that clonally expanded and transcriptionally distinct lymphocytes populate the aged central nervous system in miceYermanos, Alexander; Neumeier, Daniel; Sandu, Ioana; Borsa, Mariana; ... Reddy, Sai T
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Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasionLentini, Gaëlle; Ben Chaabene, Rouaa; Vadas, Oscar; Ramakrishnan, Chandra; ... Soldati-Favre, Dominique
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The case for simplifying and using absolute targets for viral hepatitis elimination goalsNegro, Francesco;
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The changing context of hepatitis D.Rizzetto, Mario; Hamid, Saeed; Negro, Francesco;
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The DUF1013 protein TrcR tracks with RNA polymerase to control the bacterial cell cycle and protect against antibioticsDelaby, Marie; Varesio, Lydia M; Degeorges, Laurence; Crosson, Sean; Viollier, Patrick
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The human endogenous attentional control network includes a ventro-temporal cortical nodeSani, Ilaria; Stemmann, Heiko; Caron, Bradley; Bullock, Daniel; ... Freiwald, Winrich A.
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The Janus kinase inhibitor ruxolitinib prevents terminal shock in a mouse model of arenavirus hemorrhagic feverSahin, Mehmet; Remy, Melissa M; Merkler, Doron; Pinschewer, Daniel D;
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The L1-dependant and Pol III transcribed Alu retrotransposon, from its discovery to innate immunityStenz, Ludwig;
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The p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitisBurgos, Miguel; Philippe, Reginald; Antigny, Fabrice; Buscaglia, Paul; ... Mignen, Olivier
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The relationship between EEG and fMRI connectomes is reproducible across simultaneous EEG-fMRI studies from 1.5T to 7T.Wirsich, Jonathan; Jorge, João; Iannotti, Giannina Rita; Shamshiri, Elhum Anahit; ... Vulliemoz, Serge
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Three cases of BRAF mutation negative Erdheim-Chester disease with a challenging distinction from IgG4-related diseaseSpoerl, David; Andre, Raphaël; Bornand, Aurélie; Seebach, Jorg Dieter;
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TSPO PET imaging of natalizumab-associated progressive multifocal leukoencephalopathyMahler, Christoph; Schumacher, Adrian-Minh; Unterrainer, Marcus; Kaiser, Lena; ... Kerschensteiner, Martin
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Tumor-specific cytolytic CD4 T cells mediate immunity against human cancerCachot, Amélie; Bilous, Mariia; Liu, Yen-Cheng; Li, Xiaokang; ... Jandus, Camilla
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Ultrafast pulse shaping modulates perceived visual brightness in living animalsGaulier, Geoffrey; Dietschi, Quentin; Bhattacharyya, Swarnendu; Schmidt, Cédric; ... Wolf, Jean-Pierre
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Visualization of respiratory commensal bacteria in context of their natural host environmentPereira Bonifacio Lopes, Joao Pedro; Schmolke, Mirco;
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Whole blood serotonin levels in healthy elderly are negatively associated with the functional activity of emotion-related brain regionsDeza, Yacila; Baez Lugo, Sebastian; Vuilleumier, Patrik; Chocat, Anne; ... Klimecki, Olga M.
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Whole blood thromboelastometry by ROTEM and thrombin generation by genesia according to the genotype and clinical phenotype in congenital fibrinogen disordersSzanto, Timea; Lassila, Riitta; Lemponen, Marja; Lehtinen, Elina; ... Casini, Alessandro

Book Chapters

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Biosensors monitor ligand-selective effects at kappa opioid receptorsOberhauser, Lucie; Stoeber, Miriam Carolin;

Doctoral Thesis

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Caractérisation morphologique d'un modèle CEP amélioré de DMLA atrophiqueTobalem, Stéphan Jonathan;
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