Département de physiologie cellulaire et métabolisme

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2017

Scientific Articles

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Bone Regulates Browning and Energy Metabolism Through Mature Osteoblast/Osteocyte PPARγ ExpressionBrun, Julia; Berthou, Flavien; Trajkovski, Mirko; Maechler, Pierre; ... Bonnet, Nicolas
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Diabetes Present and FutureCoppari, Roberto;
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Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genesShcherbina, L.; Edlund, A.; Esguerra, J.L.S.; Abels, M.; ... Wierup, N.
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Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state?Pournourmohammadi, Shirin; Grimaldi, Mariagrazia; Stridh, Malin H; Lavallard, Vanessa; ... Maechler, Pierre
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ER-mitochondria contacts control surface glycan expression and sensitivity to killer lymphocytes in glioma stem-like cellsBassoy, Esen; Kasahara, Atsuko; Chiusolo, Valentina; Jacquemin, Guillaume; ... Martinvalet, Denis
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Glutamate pathways of the beta-cell and the control of insulin secretionMaechler, Pierre;
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Identification of a novel population of highly cytotoxic c-Met-expressing CD8(+) T lymphocytesBenkhoucha, Mahdia; Molnarfi, Nicolas; Kaya, Gurkan; Belnoue, Elodie; ... Lalive d'Epinay, Patrice
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Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemiaGrimaldi, Mariagrazia; Karaca Emre, Melis; Latini, Livia; Brioudes, Estelle; ... Maechler, Pierre
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Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitroLoizides-Mangold, Ursula; Perrin, Laurent; Vandereycken, Bart; Betts, James A; ... Dibner, Charna
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ORAI1 Mutations with Distinct Channel Gating Defects in Tubular Aggregate MyopathyBöhm, Johann; Bulla, Monica; Urquhart, Jill E; Malfatti, Edoardo; ... Laporte, Jocelyn
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Oxidative stress and calcium dysregulation by palmitate in type 2 diabetesLy, Luong Dai; Xu, Shanhua; Choi, Seong-Kyung; Ha, Chae-Myeong; ... Park, Kyu-Sang
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Primary cilia control the maturation of tubular lumen in renal collecting duct epitheliumErnandez, Thomas; Komarynets, Olga; Chassot, Alexandra; Sougoumarin, Soushma; ... Feraille, Eric
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SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase ActivityIoris, Rafael M.; Galie, Mirco; Ramadori, Giorgio; Anderson, Jason G.; ... Coppari, Roberto
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Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetesAxelsson, Annika S; Tubbs, Emily; Mecham, Brig; Chacko, Shaji; ... Rosengren, Anders H
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Upregulation of UCP2 in beta-cells confers partial protection against both oxidative stress and glucotoxicityLi, Ning; Karaca Emre, Melis; Maechler, Pierre;
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Vps13F links bacterial recognition and intracellular killing in DictyosteliumLeiba, Jade; Sabra, Ayman; Bodinier, Romain; Marchetti, Anna; ... Cosson, Pierre

Professional Articles

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Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host modelOuertatani, Hajer; Kicka, Sébastien; Chiriano, Gianpaolo; Harrison, Christopher F; ... Cosson, Pierre

Books

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Cell division machinery and diseaseGotta, Monica; Meraldi, Patrick;

Doctoral Thesis

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Distinct contributions of hepatic Insulin receptor and IGF-1 receptor signaling in metabolic alterations and hepatocarcinogenesis associated with hepatic PTEN deficiency in micePortius, Dorothea;
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Role of TM9 proteins in intracellular transport and sorting of transmembrane domainsVernay, Alexandre;
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Roles Of mir‑21 in The development of Non‑alcoholic fatty liver disease and hepatocellular carcinomaCalo, Nicolas Virgile;

2016

Scientific Articles

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A microfluidic cell-trapping device for single-cell tracking of host-microbe interactionsDelincé, Matthieu J; Bureau, Jean-Baptiste; Lopez Jimenez, Ana Teresa; Cosson, Pierre; ... McKinney, John D
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Activation of nicotinic acetylcholine receptors decreases apoptosis in human and female murine pancreatic isletsKlee, Philippe; Bosco, Domenico; Guerardel, Audrey; Somm, Emmanuel Paul; ... Schwitzgebel Luscher, Valérie
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Adapting anatomy teaching to surgical trends: a combination of classical dissection, medical imaging, and 3D-printing technologiesFasel, Jean; Aguiar, Diego; Kiss-Bodolay, Daniel; Montet, Xavier Cédric Rodolphe; ... Ratib, Osman
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Astrocytes spatially restrict VEGF signaling by polarized secretion and incorporation of VEGF into the actively assembling extracellular matrixEgervari, Kristof Levente; Potter, Gael; Guzman-Hernandez, Maria Luisa; Salmon, Patrick; ... Kiss, Jozsef Zoltan
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Beta-cell mitochondrial carriers and the diabetogenic stress responseBrun, Thierry; Maechler, Pierre;
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Bowel function and quality of life after superior mesenteric nerve plexus transection in right colectomy with D3 extended mesenterectomyThorsen, Y.; Stimec, Bojan; Andersen, S. N.; Lindstrom, J. C.; ... Ignjatovic, D.
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Caloric Restriction Leads to Browning of White Adipose Tissue through Type 2 Immune SignalingFabbiano, Salvatore; Suarez Zamorano, Nicolas; Rigo, Dorothée; Veyrat-Durebex, Christelle; ... Trajkovski, Mirko
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Cdk1 Phosphorylates SPAT-1/Bora to Promote Plk1 Activation in C. elegans and Human CellsThomas, Yann; Cirillo, Luca; Panbianco, Costanza; Martino, Lisa; ... Gotta, Monica
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Centrosomes in spindle organization and chromosome segregation: a mechanistic viewMeraldi, Patrick;
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Channels and transporters in cell metabolismSonveaux, Pierre; Maechler, Pierre; Martinou, Jean-Claude;
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Clinical utility of 18F-FDG-PET/MR for preoperative breast cancer stagingBotsikas, Diomidis; Kalovidouri, Anastasia; Becker, Minerva; Copercini, Michele; ... Tabouret Viaud, Claire
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Compartmentalization of the endoplasmic reticulum in the early C. elegans embryosLee, Zuo Yen; Prouteau, Manoel; Gotta, Monica; Barral, Yves;
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Evaluating Preoperative Models: A Methodologic ContributionFasel, Jean; Uldin, Tanya; Vaucher, Paul; Beinemann, Joerg; ... Schaller, Karl Lothard
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Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetesPrasad, Rashmi B; Lessmark, Anna; Almgren, Peter; Kovacs, Györgyi; ... Groop, Leif
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Functional and Molecular Adaptations of Enteroendocrine L-Cells in Male Obese Mice Are Associated With Preservation of Pancreatic α-Cell Function and Prevention of HyperglycemiaDusaulcy, Rodolphe; Handgraaf, Sandra Gabrielle; Skarupelova, Svetlana; Visentin, Florian; ... Gosmain, Yvan
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Geneva road map for clinical anatomy teachingFasel, Jean;
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Glioma Stemlike Cells Enhance the Killing of Glioma Differentiated Cells by Cytotoxic LymphocytesBassoy, Esen; Chiusolo, Valentina; Jacquemin, Guillaume; Riccadonna, Cristina; ... Martinvalet, Denis
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IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell deathRutti Roch, Sabine; Howald, Cédric; Arous, Caroline; Dermitzakis, Emmanouil; ... Bouzakri, Karim
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In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhASlepikas, Liudas; Chiriano, Gianpaolo; Perozzo, Remo; Tardy, Sébastien; ... Scapozza, Leonardo
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Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β CellsSchmidt, Søren Fisker; Madsen, Jesper Grud Skat; Frafjord, Kari Østerli; Poulsen, Lars la Cour; ... Mandrup, Susanne
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Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high phosphate-induced mitochondrial oxidative stress and defective insulin secretionNguyen, Tuyet Thi; Quan, Xianglan; Xu, Shanhua; Das, Ranjan; ... Park, Kyu-Sang
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Leptin as a Potential Regulator of FGF21Asrih, Mohamed; Veyrat-Durebex, Christelle; Poher, Anne-Laure; Lyautey, Jacqueline; ... Jornayvaz, François
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Low Dose BCG Infection as a Model for Macrophage Activation Maintaining Cell ViabilityChávez-Galán, Leslie; Vesin, Marie-Dominique; Martinvalet, Denis; Garcia, Irène;
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Mechanosensing in cell-matrix adhesions - Converting tension into chemical signalsHytönen, Vesa P; Wehrle-Haller, Bernhard;
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Microbial signals to the brain control weightTrajkovski, Mirko; Wollheim, Claes;
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Mitochondrial Flashes: Dump Superoxide and Dance with Protons NowDemaurex, Nicolas; Schwarzländer, Markus;
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Neutrophils: Their Role in Innate and Adaptive ImmunityRosales, Carlos; Demaurex, Nicolas; Lowell, Clifford A; Uribe-Querol, Eileen;
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New Magnetic Resonance Imaging Index for Renal Fibrosis Assessment: A Comparison between Diffusion-Weighted Imaging and T1 Mapping with Histological ValidationFriedli, Iris; Crowe, Lindsey; Berchtold, Lena; Moll, Solange; ... Vallée, Jean-Paul
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Omega-3 Fatty Acids Protect Fatty and Lean Mouse Livers After Major HepatectomyLinecker, Michael; Limani, Perparim; Kambakamba, Patryk; Kron, Philipp; ... Clavien, Pierre-Alain
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Phosphatase and tensin homolog is a differential diagnostic marker between nonalcoholic and alcoholic fatty liver diseaseSanchez, Andréa; Clement, Sophie; Peyrou, Marion; Spahr, Laurent François Joséph; ... Foti, Michelangelo
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Preserving of Postnatal Leptin Signaling in Obesity-Resistant Lou/C Rats following a Perinatal High-Fat DietPoher, Anne-Laure; Arsenijevic, Denis; Asrih, Mohamed; Dulloo, Abdul G; ... Veyrat-Durebex, Christelle
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Pycnosomes: Condensed Endosomal Structures Secreted by Dictyostelium AmoebaeSabra, Ayman; Leiba, Jade; Mas, Lauriane; Louwagie, Mathilde; ... Aubry, Laurence
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Recombinant Antibodies for Academia: A Practical ApproachCosson, Pierre; Hartley, Oliver;
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Redox modulation of STIM-ORAI signalingBhardwaj, Rajesh; Hediger, Matthias A; Demaurex, Nicolas;
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Repair of Large Abdominal Wall Defects Using Total Anterior Aponeurotic Flap: Anatomical Feasibility Study and Comparison with Ramirez's TechniqueStaszewicz, Wojciech; Assalino, Michela; Morel, Philippe; Fasel, Jean; ... Tobalem, Mickael
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Role of SpdA in Cell Spreading and Phagocytosis in DictyosteliumDias, Marco; Brochetta, Cristiana; Marchetti, Anna; Bodinier, Romain; ... Cosson, Pierre
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Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumptionCalo, Nicolas Virgile; Ramadori, Pierluigi; Sobolewski, Cyril; Romero, Yannick; ... Foti, Michelangelo
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Syndesmosis reduction by computer-assisted orthopaedic surgery with navigation: Feasibility and accuracy in a cadaveric studyDubois-Ferriere, Victor; Gamulin, Axel Dorian G.; Chowdhary, Ashwin; Fasel, Jean; ... Assal, Mathieu
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The Amplifying Pathway of the β-Cell Contributes to Diet-induced ObesityVetterli, Laurene Marine; Carobbio, Stefania; Frigerio, Francesca; Karaca Emre, Melis; Maechler, Pierre
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The antidepressant fluoxetine induces necrosis by energy depletion and mitochondrial calcium overloadCharles, Emilie; Hammadi, Mehdi; Kischel, Philippe; Delcroix, Vanessa; ... Vacher, Pierre
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The Circadian Clock in the Ventromedial Hypothalamus Controls Cyclic Energy ExpenditureOrozco-Solis, Ricardo; Aguilar-Arnal, Lorena; Murakami, Mari; Peruquetti, Rita; ... Sassone-Corsi, Paolo
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The role of STIM and ORAI proteins in phagocytic immune cellsDemaurex, Nicolas; Nunes, Paula;
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The Ska complex promotes Aurora B activity to ensure chromosome biorientationRedli, Patrick M; Gasic, Ivana; Meraldi, Patrick; Nigg, Erich A; Santamaria, Anna
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The Staphylococcus aureus Chaperone PrsA Is a New Auxiliary Factor of Oxacillin Resistance Affecting Penicillin-Binding Protein 2A.Jousselin, Ambre; Manzano, Caroline Stéphanie; Biette, Alexandra; Reed, Patricia; ... Renzoni, Adriana Maria

Professional Articles

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Même pas malKapanci, Lana; Langhart, Julia; Lembo, Antonio Benjamin; Shore, Carolina; ... Cosson, Pierre

Doctoral Thesis

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Mitochondrial morphology and ER-mitochondria contacts regulate glioma stemlike cell surface glycan expression and sensitivity to cytotoxic lymphocytesBassoy, Esen;
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Sam50 and Tim22: a novel mitochondrial gate for the import of Granzyme BChiusolo, Valentina;
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Studies on S445L GDH mutation associated with both Hyperinsulinism/Hyperammonemia syndrome and epilepsyGrimaldi, Mariagrazia;
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The role of junctate in the regulation of phagocytosisGuido, Danièle;
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The role of paxillin in the signalling of the alphavbeta3/talin/kindlin complexVazquez Pico, Patricia;

2015

Scientific Articles

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3D Reconstruction of a Primary Aortoenteric Fistula – Centerline Calculation and MeasurementsStimec, Bojan; Fasel, Jean; Ignjatovic, Dejan;
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Accuracy evaluation of CAD/CAM generated splints in orthognathic surgery: a cadaveric studySchouman, Thomas; Rouch, Philippe; Imholz, Benoît; Fasel, Jean; ... Scolozzi, Paolo
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Adrenergic antagonists restrict replication of LegionellaHarrison, Christopher F; Kicka, Sébastien; Kranjc Pietrucci, Agata; Finsel, Ivo; ... Hilbi, Hubert
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Airway Epithelial Cell Integrity Protects from Cytotoxicity of P. aeruginosa Quorum-sensing SignalsLosa, Davide; Kohler, Thilo; Bacchetta, Marc; Bou Saab, Joanna; ... Chanson, Marc
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Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophilaHarrison, Christopher F.; Chiriano, Gianpaolo; Finsel, Ivo; Manske, Christian; ... Hilbi, Hubert
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Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted InfectionSommerstein, Rami; Flatz, Lukas Roland; Remy, Mélissa; Malinge, Pauline; ... Pinschewer, Daniel
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Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs?Wollheim, Claes; Maechler, Pierre;
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Brown adipose tissue activity as a target for the treatment of obesity/insulin resistancePoher, Anne-Laure; Altirriba Gutierrez, Jorge; Veyrat-Durebex, Christelle; Rohner-Jeanrenaud, Françoise;
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C11orf83, a Mitochondrial Cardiolipin-Binding Protein Involved in bc1 Complex Assembly and Supercomplex StabilizationDesmurs-Rousseau, Marjorie; Foti, Michelangelo; Raemy, Etienne; Vaz, Frédéric Maxime; ... Lane, Lydie
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Cdk1 phosphorylates SPAT-1/Bora to trigger PLK-1 activation and drive mitotic entry in C. elegans embryosTavernier, Nicolas; Bernasconi-Noatynska, Anna; Panbianco, Costanza; Martino, Lisa; ... Pintard, Lionel
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Cellular and molecular effects of the mTOR inhibitor everolimusSaran, Uttara; Foti, Michelangelo; Dufour, Jean-François;
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Centrosome age regulates kinetochore-microtubule stability and biases chromosome mis-segregationGasic, Ivana; Nerurkar, Purnima; Meraldi, Patrick;
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Chronic Oxytocin Administration as a Treatment Against Impaired Leptin Signaling or Leptin Resistance in ObesityAltirriba Gutierrez, Jorge; Poher, Anne-Laure; Rohner-Jeanrenaud, Françoise;
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CRL4RBBP7 is required for efficient CENP-A deposition at centromeresMouysset, Julien; Gilberto, Samuel; Meier, Michelle; Lampert, Fabienne; ... Peter, Matthias
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Cytoplasmic methylation fuels leukocyte invasionWehrle-Haller, Bernhard;
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Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic isletsBrun, Thierry; Li, Ning; Jourdain, Alexis; Gaudet, Pascale; ... Maechler, Pierre
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Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung TumorigenesisRamadori, Giorgio; Konstantinidou, Georgia; Venkateswaran, Niranjan; Biscotti, Tommasina; ... Coppari, Roberto
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Ectopic UCP1 Overexpression in White Adipose Tissue Improves Insulin Sensitivity in Lou/C Rats, a Model of Obesity ResistancePoher, Anne-Laure; Veyrat-Durebex, Christelle; Altirriba Gutierrez, Jorge; Montet, Xavier Cédric Rodolphe; ... Rohner-Jeanrenaud, Françoise
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Effets métaboliques de l’ocytocine et ses applications potentielles pour le traitement de l’obésitéAltirriba Gutierrez, Jorge; Pataky, Zoltan; Golay, Alain; Rohner-Jeanrenaud, Françoise;
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Endocrine control of energy homeostasisRohner-Jeanrenaud, Françoise; Nogueiras, Ruben;
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Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6Anderson, Jason G.; Ramadori, Giorgio; Ioris, Rafael M.; Galie, Mirco; ... Coppari, Roberto
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Erratum to "Adipokines at the crossroad between obesity and cardiovascular disease" (Thromb Haemost 2015; 113: 553-566)Molica, Filippo; Morel, Sandrine; Kwak, Brenda; Rohner-Jeanrenaud, Françoise; Steffens, Sabine
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Essential Role of Mitochondrial Ca2+ Uniporter in the Generation of Mitochondrial pH Gradient and Metabolism-Secretion Coupling in Insulin-releasing CellsQuan, Xianglan; Nguyen, Tuyet Thi; Choi, Seong-Kyung; Xu, Shanhua; ... Park, Kyu-Sang
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GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate DistributionKaraca Emre, Melis; Frigerio, Francesca; Migrenne, Stephanie; Martin-Levilain, Juliette; ... Maechler, Pierre
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Gut Microbiota Orchestrates Energy Homeostasis during ColdChevalier, Claire; Stojanovic, Ozren; Colin, Didier; Suarez Zamorano, Nicolas; ... Trajkovski, Mirko
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Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in micePeyrou, Marion; Bourgoin, Lucie; Poher, Anne-Laure; Altirriba Gutierrez, Jorge; ... Foti, Michelangelo
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Hyaluronic Acid Filler in HIV-Associated Facial Lipoatrophy: Evaluation of Tissue Distribution and Morphology with MRI.Becker, Minerva; Balague, Nicolas; Montet, Xavier Cédric Rodolphe; Calmy, Alexandra; ... Toutous-Trellu, Laurence
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Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemiaTaneera, J.; Fadista, J.; Ahlqvist, E; Atac, D.; ... Groop, L.
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Image quality of low mA CT pulmonary angiography reconstructed with model based iterative reconstruction versus standard CT pulmonary angiography reconstructed with filtered back projection: an equivalency trialMontet, Xavier Cédric Rodolphe; Hachulla-Lemaire, Anne-Lise; Neroladaki, Angeliki; Lador, Frédéric; ... Becker, Christoph
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