Institut de génétique et de génomique

Show items per page
Elements: 130
Page 1 on 2

2021

Scientific Articles

add to browser selection
Blood virosphere in febrile Tanzanian childrenCordey, Samuel; Laubscher, Florian; Hartley, Mary-Anne; Junier, Thomas; ... Kaiser, Laurent
add to browser selection
Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancerRouco, Raquel; Bompadre, Olimpia; Rauseo, Antonella; Fazio, Olivier; ... Andrey, Guillaume
add to browser selection
Chemical modulators of fibrinogen production and their impact on venous thrombosisFerreira Vilar Da Silva, Rui Filipe; Lukowski, Samuel; Garieri, Marco; Di Sanza, Corinne; ... Fish, Richard
add to browser selection
Circadian clocks guide dendritic cells into skin lymphaticsHoltkamp, Stephan J.; Ince, Louise; Barnoud, Coline; Schmitt, Madeleine T.; ... Scheiermann, Christoph
add to browser selection
Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocksSinturel, Flore; Gos, Pascal; Petrenko, Volodymyr; Hagedorn, Claudia; ... Schibler, Ueli
add to browser selection
Circadian Lipidomics: Analysis of Lipid Metabolites Around the ClockLoizides-Mangold, Ursula Elfriede; Petrenko, Volodymyr; Dibner, Charna;
add to browser selection
Drug repurposing to identify a synergistic high-order drug combination to treat sunitinib-resistant renal cell carcinomaRausch, Magdalena; Rutz, Adriano; Allard, Pierre-Marie; Delucinge, Céline; ... Nowak-Sliwinska, Patrycja
add to browser selection
Dynamic dichotomy of accumbal population activity underlies cocaine sensitizationVan Zessen, Ruud; Li, Yue; Marion-Poll, Lucile; Hulo, Nicolas; ... Luscher, Christian
add to browser selection
eIF4E3 forms an active eIF4F complex during stresses (eIF4FS) targeting mTOR and re-programs the translatomeWeiss, Benjamin; Allen, George Edward; Kloehn, Joachim; Abid, Karim; ... Curran, Joseph
add to browser selection
Estimating clinical SARS-CoV-2 infectiousness in Vero E6 and primary airway epithelial cellsEssaidi, Manel; Perez Rodriguez, Francisco Javier; Hulo, Nicolas; Jacquerioz, Frédérique Aline; ... Eckerle, Isabella Anne
add to browser selection
Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patientsHannich, Joerg Thomas; Loizides-Mangold, Ursula Elfriede; Sinturel, Flore; Harayama, Takeshi; ... Dibner, Charna
add to browser selection
High throughput screening identifies SOX2 as a super pioneer factor that inhibits DNA methylation maintenance at its binding sitesVanzan, Ludovica; Soldati, Hadrien; Ythier, Victor; Anand, Santosh; ... Murr, Rabih
add to browser selection
Molecular and Functional Analysis of Sunitinib-Resistance Induction in Human Renal Cell Carcinoma CellsRausch, Magdalena; Rutz, Adriano; Allard, Pierre-Marie; Delucinge, Céline; ... Nowak-Sliwinska, Patrycja
add to browser selection
Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulatorAllou, Lila; Andrey, Guillaume; Superti-Furga, Andrea;
add to browser selection
Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5AAllen, George Edward; Panasenko, Olesya; Villanyi, Zoltan; Zagatti, Marina; ... Collart, Martine
add to browser selection
Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin productionPerez Frances, Marta; Van Gurp, Léon; Abate, Maria Valentina; Cigliola, Valentina; ... Herrera, Pedro Luis
add to browser selection
Patients with elevated basal tryptase serum levels should be tested for hereditary alpha-tryptasemiaSpoerl, David; Docquier, Mylene; Coattrenec, Yann; Seebach, Jorg Dieter;
add to browser selection
Perception and Signaling of Ultraviolet-B Radiation in PlantsPodolec, Roman; Demarsy, Emilie; Ulm, Roman;
add to browser selection
PQN-59 and GTBP-1 contribute to stress granule formation but are not essential for their assembly in C. elegans embryosAbbatemarco, Simona; Bondaz, Alexandra; Schwager, Françoise; Wang, Jing; ... Gotta, Monica
add to browser selection
Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determinationMayere, Chloé; Neirijnck, Yasmine; Sararols, Pauline; Rands, Christopher; ... Nef, Serge
add to browser selection
Specific transcriptomic signatures and dual regulation of steroidogenesis between fetal and adult mouse leydig cellsSararols, Pauline; Stevant, Isabelle; Neirijnck, Yasmine; Rebourcet, Diane; ... Nef, Serge
add to browser selection
Stage-specific transcriptomic changes in pancreatic α-cells after massive β-cell lossOropeza, Daniel; Cigliola, Valentina; Romero, Agustín; Chera, Simona; ... Herrera, Pedro Luis
add to browser selection
The ULK1 kinase, a necessary component of the pro-regenerative and anti-aging machinery in HydraSuknovic, Nenad Slavko; Tomczyk, Szymon; Colevret, Delphine; Perruchoud, Chrystelle; Galliot, Brigitte
add to browser selection
Transgenerational inheritance of centromere identity requires the CENP-A N-terminal tail in the C. elegans maternal germ lineProsee, Reinier; Wenda, Joanna; Ozdemir, Isa; Gabus, Caroline; ... Steiner, Florian
add to browser selection
Unmasking viral sequences by metagenomic next-generation sequencing in adult human blood samples during steroid-refractory/dependent graft-versus-host diseaseZanella, Marie-Céline; Cordey, Samuel; Laubscher, Florian; Docquier, Mylene; ... Vu Cantero, Diem-Lan

2020

Scientific Articles

add to browser selection
ATLAS: a snakemake workflow for assembly, annotation, and genomic binning of metagenome sequence dataKieser, Silas; Brown, Joseph; Zdobnov, Evgeny; Trajkovski, Mirko; McCue, Lee Ann
add to browser selection
Binding affinities of 438 hla proteins to complete proteomes of seven pandemic viruses and distributions of strongest and weakest hla peptide binders in populations worldwideBarquera, Rodrigo; Collen, Evelyn; Di, Da; Buhler, Stéphane; ... Sanchez-Mazas, Alicia
add to browser selection
Circadian clocks make metabolism runSinturel, Flore; Petrenko, Volodymyr; Dibner, Charna;
add to browser selection
Contribution of exome sequencing to the identification of genes involved in the response to clopidogrel in cardiovascular patientsFontana, Pierre; Ibberson, Mark; Stevenson, Brian; Wigger, Leonore; ... Reny, Jean-Luc
add to browser selection
Coupled network of the circadian clocks: a driving force of rhythmic physiologyFinger, Anna-Marie; Dibner, Charna; Kramer, Achim;
add to browser selection
Cryptochrome-mediated blue-light signalling modulates UVR8 photoreceptor activity and contributes to UV-B tolerance in ArabidopsisTissot, Nicolas; Ulm, Roman;
add to browser selection
Degradation of the transcription factors PIF4 and PIF5 under UV-B promotes UVR8-mediated inhibition of hypocotyl growth in ArabidopsisTavridou, Eleni; Pireyre, Marie; Ulm, Roman;
add to browser selection
Fibrin(ogen) in human disease: both friend and foeFerreira Vilar Da Silva, Rui Filipe; Fish, Richard; Casini, Alessandro; Neerman Arbez, Marguerite;
add to browser selection
FKBP10 regulates protein translation to sustain lung cancer growthRamadori, Giorgio; Ioris, Rafael M; Villanyi, Zoltan; Firnkes, Raquel; ... Coppari, Roberto
add to browser selection
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D.Vinuela Rodriguez, Ana; Brown, Andrew Anand; Howald, Cédric; Panousis, Nikolaos; ... McCarthy, Mark I
add to browser selection
Identification and expression of a novel heterozygous frameshift mutation in FGA accounting for congenital hypofibrinogenemia in carriers of severe hemophilia A.Ferreira Vilar Da Silva, Rui Filipe; Casini, Alessandro; Fournel, Alexandra; Mourey, Guillaume; Neerman Arbez, Marguerite
add to browser selection
In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosisPetrenko, Volodymyr; Gandasi, Nikhil R; Sage, Daniel; Tengholm, Anders; ... Dibner, Charna
add to browser selection
Influence of Paleolithic range contraction, admixture and long‐distance dispersal on genetic gradients of modern humans in AsiaBranco, Catarina; Ray, Nicolas; Currat, Mathias; Arenas, Miguel;
add to browser selection
Integrative and quantitative view of the CtrA regulatory network in a stalked budding bacteriumLeicht, Oliver; van Teeseling, Muriel C F; Panis, Gaël; Reif, Celine; ... Thanbichler, Martin
add to browser selection
Loss of bacterial cell pole stabilization in caulobacter crescentus sensitizes to outer membrane stress and peptidoglycan-directed antibioticsVallet, Simon; Hansen, Lykke Haastrup; Bistrup, Freja Cecillie; Laursen, Signe Aagaard; ... Kirkpatrick, Clare
add to browser selection
MCF2 is linked to a complex perisylvian syndrome and affects cortical laminationMolinard-Chenu, Aude; Fluss, Joël Victor; Laurent, Sacha; Laurent, Meryle; ... Dayer, Alexandre
add to browser selection
Methods to investigate miRNA function: focus on platelet reactivityGarcia, Alix; Geindre, Sylvie Françoise; Fish, Richard; Neerman Arbez, Marguerite; ... Fontana, Pierre
add to browser selection
Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatmentZoetemelk, Marloes; Ramzy, George Mourad; Rausch, Magdalena; Kossler, Thibaud; ... Nowak-Sliwinska, Patrycja
add to browser selection
Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic OriginsRollason, Victoria; Mouterde, Médéric; Daali, Youssef; Čížková, Martina; ... Desmeules, Jules Alexandre
add to browser selection
Taurine treatment of retinal degeneration and cardiomyopathy in a consanguineous family with SLC6A6 taurine transporter deficiencyAnsar, Muhammad; Ranza, Emmanuelle Nathalie; Shetty, Madhur; Paracha, Sohail A; ... Antonarakis, Stylianos
add to browser selection
The core clock transcription factor BMAL1 drives circadian β-cell proliferation during compensatory regeneration of the endocrine pancreasPetrenko, Volodymyr; Stolovich-Rain, Miri; Vandereycken, Bart; Morele Giovannoni, Laurianne; ... Dibner, Charna
add to browser selection
The GLP-1R agonist liraglutide limits hepatic lipotoxicity and inflammatory response in mice fed a methionine-choline deficient dietSomm, Emmanuel; Montandon, Sophie Anne; Loizides-Mangold, Ursula Elfriede; Gaia, Nadia; ... Jornayvaz, François
add to browser selection
Unbiased metagenomic next-generation sequencing of blood from hospitalized febrile children in GabonFernandes, José Francisco; Laubscher, Florian; Held, Jana; Eckerle, Isabella Anne; ... Cordey, Samuel
add to browser selection
UVR8-mediated inhibition of shade avoidance involves HFR1 stabilization in ArabidopsisTavridou, Eleni; Schmid-Siegert, Emanuel; Fankhauser, Christian; Ulm, Roman;

2019

Scientific Articles

add to browser selection
A spoIID homolog cleaves glycan strands at the chlamydial division septumJacquier, Nicolas; Yadav, Akhilesh K; Pillonel, Trestan; Viollier, Patrick; ... Greub, Gilbert Daniel
add to browser selection
Accurate, scalable and integrative haplotype estimationDelaneau, Olivier; Zagury, Jean-François; Robinson, Matthew R; Marchini, Jonathan L; Dermitzakis, Emmanouil
add to browser selection
Cellular circadian period length inversely correlates with HbA1c levels in individuals with type 2 diabetesSinturel, Flore; Makhlouf, Anne-Marie; Meyer, Patrick; Tran, Christel; ... Dibner, Charna
add to browser selection
Chromatin three-dimensional interactions mediate genetic effects on gene expressionDelaneau, Olivier; Zazhytska, M; Borel, Christelle; Giannuzzi, G; ... Dermitzakis, Emmanouil
add to browser selection
Chromatin topology in development and diseaseBompadre, Olimpia; Andrey, Guillaume;
add to browser selection
Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severityPanousis, Nikolaos; Bertsias, George K; Ongen, Halit; Gergianaki, Irini; ... Boumpas, Dimitrios T
add to browser selection
Detection of dicistroviruses RNA in blood of febrile Tanzanian childrenCordey, Samuel; Laubscher, Florian; Hartley, Mary-Anne; Junier, Thomas; ... Kaiser, Laurent
add to browser selection
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT ConsortiumKoivula, Robert W; Vinuela Rodriguez, Ana; Dermitzakis, Emmanouil; Franks, Paul W;
add to browser selection
Dissecting Cell Lineage Specification and Sex Fate Determination in Gonadal Somatic Cells Using Single-Cell TranscriptomicsStevant, Isabelle; Kuhne, Françoise; Greenfield, Andy; Chaboissier, Marie-Christine; ... Nef, Serge
add to browser selection
Does NGS typing highlight our understanding of HLA population diversity?: Some good reasons to say yes and a few to say be carefulSanchez-Mazas, Alicia; Nunes, Jose Manuel;
add to browser selection
Expression of the DNA-binding factor TOX promotes the encephalitogenic potential of microbe-induced autoreactive CD8+ T cellsPage, Nicolas; Klimek, Bogna; De Roo, Mathias; Steinbach, Karin; ... Merkler, Doron
add to browser selection
Genetic Control of Gonadal Sex Determination and DevelopmentStevant, Isabelle; Nef, Serge;
add to browser selection
High-resolution HLA phased haplotype frequencies to predict the success of unrelated donor searches and clinical outcome following hematopoietic stem cell transplantationBuhler, Stéphane; Baldomero, Helen; Ferrari-Lacraz, Sylvie; Nunes, Jose Manuel; ... Villard, Jean
add to browser selection
Hybridization and introgression during density-dependent range expansion: European wildcats as a case studyQuilodran, Claudio; Nussberger, Beatrice; Montoya Burgos, Juan Ignacio; Currat, Mathias;
add to browser selection
Identification of new DNA-associated proteins from Waddlia chondrophilaBarsy, Marie de; Herrgott, Lucas; Martin, Virginie; Pillonel, Trestan; ... Greub, Gilbert
add to browser selection
Loss of neurogenesis in aging HydraTomczyk, Szymon; Buzgariu, Wanda Christa; Perruchoud, Chrystelle; Fisher, Kathleen; ... Galliot, Brigitte
add to browser selection
Microbiota guides insulin trafficking in beta cellsStojanovic, Ozren; Trajkovski, Mirko;
add to browser selection
Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolismMontandon, Sophie; Somm, Emmanuel; Loizides-Mangold, Ursula; De Vito, Claudio; ... Jornayvaz, François
add to browser selection
Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2)Zingg, Walter; Park, Benjamin J.; Storr, Julie; Ahmad, Raheelah; ... Ndoye, Babacar
add to browser selection
The importance of being rhythmic: living in harmony with your body clocksDibner, Charna;
add to browser selection
Validation of molecular biomarkers for preoperative diagnostics of human papillary thyroid carcinoma in fine needle aspiratesSadowski Veuthey, Mercedes Samira Doris; Petrenko, Volodymyr; Meyer, Patrick; Pusztaszeri, Marc; ... Dibner, Charna
add to browser selection
Viral sequences detection by high-throughput sequencing in cerebrospinal fluid of individuals with and without central nervous system diseaseSchibler, Manuel; Brito, Francisco; Zanella, Marie-Céline; Zdobnov, Evgeny; ... Kaiser, Laurent

2018

Scientific Articles

add to browser selection
A dock-and-lock mechanism clusters ADAM10 at cell-cell junctions to promote α-toxin cytotoxicityShah, Jimit; Rouaud, Florian; Guerrera, Diego; Vasileva, Ekaterina; ... Citi, Sandra
add to browser selection
Age-dependent changes in mean and variance of gene expression across tissues in a twin cohortVinuela Rodriguez, Ana; Brown, Andrew Anand; Buil Demur, Alfonso Alberto; Tsai, Pei-Chien; ... Small, Kerrin S
add to browser selection
Angiogenin and osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokinesRutti Roch, Sabine; Dusaulcy, Rodolphe; Hansen, Jakob S.; Howald, Cédric; ... Bouzakri, Karim
add to browser selection
Arabidopsis RUP2 represses UVR8-mediated flowering in noninductive photoperiodsArongaus, Adriana Beatriz; Chen, Song; Pireyre, Marie; Glöckner, Nina; ... Ulm, Roman
add to browser selection
Biallelic variants in LINGO1 are associated with autosomal recessive intellectual disability, microcephaly, speech and motor delayAnsar, Muhammad; Riazuddin, Saima; Sarwar, Muhammad Tahir; Makrythanasis, Periklis; ... Antonarakis, Stylianos
add to browser selection
Body clocks: Time for the Nobel PrizeDibner, Charna; Schibler, Ulrich;
add to browser selection
Common traits between the beige fat-inducing stimuliStojanovic, Ozren; Kieser, Silas; Trajkovski, Mirko;
add to browser selection
Comprehensive evaluation of coding region point mutations in microsatellite‐unstable colorectal cancerKondelin, Johanna; Salokas, Kari; Saarinen, Lilli; Ovaska, Kristian; ... Aaltonen, Lauri A
add to browser selection
Coping with 'Dark Sides of the Sun' through Photoreceptor SignalingDemarsy, Emilie; Goldschmidt-Clermont, Michel P.; Ulm, Roman;
add to browser selection
Deciphering the fine nucleotide diversity of full HLA class I and class II genes in a well-documented population from sub-Saharan AfricaGoeury, Thomas; Creary, L E; Brunet, Lydie; Galan, M; ... Sanchez-Mazas, Alicia
add to browser selection
Effect of hybridization with genome exclusion on extinction riskQuilodran, Claudio; Currat, Mathias; Montoya Burgos, Juan Ignacio;
add to browser selection
Expression of the DNA-binding factor TOX promotes the encephalitogenic potential of microbe-induced autoreactive CD8+ T cellsPage, Nicolas; Klimek, Bogna; De Roo, Mathias; Steinbach, Karin; ... Merkler, Doron
add to browser selection
Mandenka from Senegal: Next Generation Sequencing typings reveal very high frequencies of particular HLA class II alleles and haplotypesGoeury, Thomas; Creary, L E; Fernandez-Vina, M A; Tiercy, Jean-Marie; ... Sanchez-Mazas, Alicia
add to browser selection
MRPL53, a new candidate gene for orofacial clefting, identified using an eQTL approachMasotti, C.; Brito, L.A.; Nica, A.C.; Ludwig, K.U.; ... Passos-Bueno, M.R.
add to browser selection
Photoreceptor-mediated regulation of the COP1/SPA E3 ubiquitin ligasePodolec, Roman; Ulm, Roman;
add to browser selection
Regulation of Cellular Metabolism through Phase Separation of EnzymesProuteau, Manoel; Loewith, Robbie Joséph;
add to browser selection
Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal musclePerrin, Laurent; Loizides-Mangold, Ursula; Chanon, Stéphanie; Gobet, Cédric; ... Dibner, Charna
add to browser selection
Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variationGamazon, Eric R.; Segrè, Ayellet V.; van de Bunt, Martijn; Wen, Xiaoquan; ... Ardlie, Kristin G.

Professional Articles

add to browser selection
The Candidate Schizophrenia Risk Gene DGCR2 Regulates Early Steps of CorticogenesisMolinard-Chenu, Aude; Dayer, Alexandre;
<< previous | 1 | 2 |