Département d'anesthésiologie, pharmacologie et soins intensifs

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2018

Scientific Articles

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Cost-effectiveness of HLA-DQB1/HLA-B pharmacogenetic-guided treatment and blood monitoring in US patients taking clozapineGirardin, François; Poncet, Antoine; Perrier, Arnaud; Vernaz-Hegi, Nathalie; ... Villard, Jean
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Dermatoporosis: a further step to recognitionKaya, Gurkan; Kaya, Aysin; Sorg, Olivier; Saurat, J.-H.;
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Evaluation of recombinant factor VIIa, tranexamic acid and desmopressin to reduce prasugrel-related bleeding: A randomised, placebo-controlled study in a rabbit modelBonhomme, Fanny; Lecompte, Thomas Pierre; Samama, Charles M; Godier, Anne; Fontana, Pierre
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Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T CellsPage, Nicolas; Klimek, Bogna; De Roo, Mathias; Steinbach, Karin; ... Merkler, Doron
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Immune Checkpoint Inhibitor-Associated Myocarditis: A New Challenge for CardiologistsFrigeri, Mauro; Meyer, Philippe; Banfi, Carlo; Giraud, Raphaël; ... Dietrich, Pierre-Yves
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Impact of intravascular thrombosis on failure of radial arterial catheters in critically ill patients: a nested case-control studyFleury, Yvan; Arroyo, Diego; Couchepin, Caroline; Robert-Ebadi, Helia; ... Gayet-Ageron, Angèle
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In-situ split liver splitting under extra-corporeal membrane oxygenation in brain-dead donorAssalino, Michela; Majno, Pietro; Toso, Christian; Berney, Thierry; ... Elkrief, Laure
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Internists’ and intensivists’ roles in intensive care admission decisions: a qualitative studyCullati, Stéphane; Hudelson Perneger, Patricia Martha; Ricou, Bara; Nendaz, Mathieu; ... Escher, Monica
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Is team-based perception of safety in the operating room associated with self-reported wrong-site surgery? An exploratory cross-sectional survey among physiciansCullati, Stéphane; Courvoisier, Delphine; Francis, Patricia Anupama; Degiorgi, Adriana; ... Chopard, Pierre André
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Lung responses in murine models of experimental asthma: Value of house dust mite over ovalbumin sensitizationDoras, Camille; Petak, Ferenc; Bayat, Sam; Baudat, Aurélie-Djamila; ... Habre, Walid
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Management of antiplatelet therapy in patients undergoing elective invasive procedures: Proposals from the French Working Group on perioperative hemostasis (GIHP) and the French Study Group on thrombosis and hemostasis (GFHTGodier, Anne; Fontana, Pierre; Motte, Serge; Steib, Annick; ... Collet, Jean-Philippe
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Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human DiseasesGrazioli, Serge; Pugin, Jérôme;
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Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp softwareMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
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RASopathic comedone-like or cystic lesions induced by vemurafenib: a model of skin lesions similar but not identical to those induced by dioxins MADISHKaya, Gurkan; Saxer-Sekulic, Nikolina; Kaya, Aysin; Sorg, Olivier; ... Saurat, Jean-Hilaire
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When the Safe Alternative Is Not That Safe: Tramadol Prescribing in ChildrenRodieux, Frédérique; Vutskits, Laszlo; Posfay Barbe, Clara; Habre, Walid; ... Samer, Caroline Flora

Privat-docent Thesis

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Life cycle of a drug – a perspective for policy makersVernaz-Hegi, Nathalie;

2017

Scientific Articles

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"Late" Withdrawal Syndrome after Carbamazepine In Utero Exposure in a CYP2C9 Slow Metabolizer NewbornPassia, Evangelia; Rock, Nathalie; Pfister, Riccardo; Ing Lorenzini, Kuntheavy; ... Samer, Caroline Flora
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A concordance-based study to assess doctors' and nurses' mental models in Internal MedicineBlondon, Katherine; Chan, K C Gary; Muller-Juge, Virginie; Cullati, Stéphane; ... Nendaz, Mathieu
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A feasability study of color flow doppler vectorization for automated blood flow monitoringSchorer, Raoul; Badoual, A; Bastide, B; Vandebrouck, A; ... Sage, D
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A multilevel analysis of professional conflicts in health care teams: insight for future trainingBochatay, Naike; Bajwa, Nadia Masood; Cullati, Stéphane; Muller-Juge, Virginie; ... Nendaz, Mathieu
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A propos du compte rendu radiologiqueBendjelid, Karim;
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A scope on esophageal damages associated with routine transesophageal echocardiography use in cardiac surgeryAbraham, Paul Samuel; Siegenthaler, Nils; Giraud, Raphaël; Bendjelid, Karim;
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Admission aux soins intensifs d’un patient en soins palliatifs : enjeux et facteurs influençant la décisionEscher, Monica; Nendaz, Mathieu; Ricou, Bara;
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Advance care planning and major cardiovascular surgery: do patients care?Gigon, Fabienne; Combescure, Christophe; Ricou, Bara;
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Alveolar gas composition during maximal and interrupted apnoeas in ambient air and pure oxygenFagoni, Nazzareno; Taboni, Anna; Vinetti, Giovanni; Bottarelli, Sara; ... Ferretti, Guido
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Ammonium tetrathiomolybdate following ischemia/reperfusion injury: Chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury modelsDyson, Alex; Dal-Pizzol, Felipe; Sabbatini, Giovanni; Lach, Anna B; ... Singer, Mervyn
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An International, Multicenter, Observational Study of Cerebral Oxygenation during Infant and Neonatal AnesthesiaOlbrecht, Vanessa A.; Skowno, Justin; Marchesini, Vanessa; Ding, Lili; ... Davidson, Andrew
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Analyzing Structural Plasticity of Dendritic Spines in Organotypic Slice CultureDe Roo, Mathias; Ribic, Adema;
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Apixaban Pharmacokinetics at Steady State in Hemodialysis PatientsMavrakanas, Thomas A; Samer, Caroline Flora; Nessim, Sharon J; Frisch, Gershon; Lipman, Mark L
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Assessment of Haemostasis in patients undergoing emergent neurosurgery by rotational Elastometry and standard coagulation tests: a prospective observational studyEllenberger, Christoph; Garofano, Najia; Barcelos, Gleicy; Diaper, John; ... Licker, Marc
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Association of Lectin Pathway Protein Levels and Genetic Variants Early after Injury with Outcomes after Severe Traumatic Brain Injury: A Prospective Cohort StudyOsthoff, Michael; Walder, Bernhard; Delhumeau-Cartier, Cécile; Trendelenburg, Marten; Turck, Natacha
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Can We Really Suggest that Anesthesia Might Cause Attention-deficit/Hyperactivity Disorder?Efron, Daryl; Vutskits, Laszlo; Davidson, Andrew J.;
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Cardiac output-Scvo2 relationship during sepsis: A subtle associationBendjelid, Karim;
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Characterization of a metabolomic profile associated with responsiveness to therapy in the acute phase of septic shockCambiaghi, Alice; Bollen Pinto, Bernardo; Brunelli, Laura; Falcetta, Francesca; ... Ferrario, Manuela
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Characterization of Brain-Heart Interactions in a Rodent Model of SepsisBollen Pinto, Bernardo; Ritter, Cristiane; Michels, Monique; Gambarotta, Nicolò; ... Singer, Mervyn
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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferasesRomand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge
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Clinical Metagenomics for the Diagnostic of Hospital-acquired Infections: Promises and HurdlesEmonet, Stéphane Paul; Lazarevic, Vladimir; Pugin, Jérôme; Schrenzel, Jacques; Ruppe, Etienne
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Colitis ulcerosa und fulminantes Leberversagen bei einer 20-jährigen PatientinForker, R; Escher, Monica; Stange, E F;
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Contraction response to muscle percussion: A reappraisal of the mechanism of this bedside testCzarnetzki, Christoph; Truffert, André; Mekideche, Abdelhafid; Poncet, Antoine; ... Magistris, Michel R
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Creation of the Swiss group of Pharmacogenomics and personalised Therapy (SPT)Amstutz, Ursula; Mlakar, Vid; Huezo-Diaz Curtis, Patricia; Samer, Caroline Flora; ... Ansari Djaberi, Marc Georges
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Dynamics of the RR-interval versus blood pressure relationship at exercise onset in humansBringard, Aurélien; Adami, Alessandra; Fagoni, Nazzareno; Fontolliet, Timothée Matthieu; ... Ferretti, Guido
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Effect of cerebral vasomotion during physical exercise on associative memory, a near-infrared spectroscopy studyMarin Bosch, Blanca; Bringard, Aurélien; Ferretti, Guido; Schwartz, Sophie; Igloi, Kinga Katinka
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Effects of recovery interval duration on the parameters of the critical power model for incremental exerciseVinetti, Giovanni; Fagoni, Nazzareno; Taboni, Anna; Camelio, Stefano; ... Ferretti, Guido
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Energy expenditure in mechanically ventilated patients: The weight of body weight!Graf, Séverine; Pichard, Claude; Genton Graf, Laurence; Oshima, Taku; Heidegger, Claudia Paula
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Fact and controversies when assessing fluid responsivenessBendjelid, Karim;
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Fatal postoperative systemic pulmonary hypertension in benfluorex-induced valvular heart disease surgery: A case reportBaufreton, Christophe; Bruneval, Patrick; Rousselet, Marie-Christine; Ennezat, Pierre-Vladimir; ... Banfi, Carlo
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General Anesthetics to Treat Major Depressive DisorderVutskits, Laszlo;
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HeartMate 3 in Lowest INTERMACS Profile Cohort: The Swiss ExperienceBanfi, Carlo; Meyer, Philippe; Huber, Christoph; Giraud, Raphaël; ... Kirsch, Matthias
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High-fidelity simulation for extracorporeal membrane oxygenation training, utile or futile?Banfi, Carlo; Bendjelid, Karim; Giraud, Raphaël;
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Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactionsStorelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, Aurélien; ... Daali, Youssef
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Impact of intrathecal morphine analgesia on the incidence of pulmonary complications after cardiac surgery: a single center propensity-matched cohort studyEllenberger, Christoph; Sologashvili, Tornike; Bhaskaran, Krishnan; Licker, Marc;
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Improved Survival in a Long-Term Rat Model of Sepsis Is Associated With Reduced Mitochondrial Calcium Uptake Despite Increased Energetic DemandBollen Pinto, Bernardo; Dyson, Alex; Umbrello, Michele; Carré, Jane E; ... Singer, Mervyn
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Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in EuropeHabre, Walid; Disma, Nicola; Virag, Katalin; Becke, Karin; ... Veyckemans, Francis
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Intensive care in thoracic oncologyMeert, Anne-Pascale; Grigoriu, Bogdan; Licker, Marc; Van Schil, Paul E; Berghmans, Thierry
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Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic FeverRemy, Mélissa; Sahin, Mehmet; Flatz, Lukas Roland; Regen, Tommy; ... Pinschewer, Daniel
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Journal of Clinical Monitoring and Computing 2016 end of year summary: cardiovascular and hemodynamic monitoringSaugel, Bernd; Bendjelid, Karim; Critchley, Lester A; Rex, Steffen; Scheeren, Thomas W L
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K-Cl Cotransporter 2?mediated Cl? Extrusion Determines Developmental Stage?dependent Impact of Propofol Anesthesia on Dendritic SpinesPuskarjov, Martin; Fiumelli, Hubert; Briner, Adrian; Bodogan, Timea; ... Vutskits, Laszlo
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Life-threatening neuroleptic withdrawal emergent syndrome resembling status dystonicusPugin, Deborah; Bally, Julien; Horvath, Judit; Pollak, Pierre; ... Burkhard, Pierre
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Management of direct oral anticoagulants in patients undergoing elective surgeries and invasive procedures: Updated guidelines from the French Working Group on Perioperative Hemostasis (GIHP) - September 2015Albaladejo, Pierre; Bonhomme, Fanny; Blais, Normand; Collet, Jean-Philippe; ... Susen, Sophie
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Non-dominant hand quicker to insert peripheral venous catheters under echographic guidance: A randomised trialDurand-Bailloud, Lucas; Aho, Ludwig-Serge; Savoldelli, Georges Louis; Ecarnot, Fiona; ... Benkhadra, Mehdi
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Outcome of geriatric patients admitted to intensive care unit after surgery: the burden of chronic diseasesCassina, Tiziano; Licker, Marc;
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Perioperative Hypotension in Infants: Insights From the GAS StudyVutskits, Laszlo; Skowno, Justin;
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Pharmacogénomique et thérapie personnaliséeBaumann, Pierre-Pascal; Amstutz, Ursula; Bühlmann, Roland P; Meier-Abt, Peter; ... Ansari Djaberi, Marc Georges
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Physical restraint: time to let goBurry, Lisa; Rose, Louise; Ricou, Bara;
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PIM-Check: development of an international prescription-screening checklist designed by a Delphi method for internal medicine patientsDesnoyer, Aude; Blanc, Anne-Laure; Pourcher, Valérie; Besson, Marie; ... Guignard, Bertrand
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Plasma concentrations of transdermal fentanyl and buprenorphine in pigs (Sus scrofa domesticus)Osorio Lujan, Suzanne; Habre, Walid; Daali, Youssef; Pan, Zhaoxin; Kronen, Peter W
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Predicting postoperative brain function from the blood: is there a role for biomarkers?Vutskits, Laszlo;
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Prediction of Acute Postoperative Pain Following Breast Cancer Surgery Using the Pain Sensitivity Questionnaire: A Cohort StudyRehberg-Klug, Benno; Mathivon, Stanislas; Combescure, Christophe; Mercier, Yannick; Savoldelli, Georges Louis
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Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trialBluth, T; Teichmann, R; Kiss, T; Bobek, I; ... Gama de Abreu, M
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Reply to Cavalheri et alKarenovics, Wolfram; Ellenberger, Christoph; Triponez, Frédéric; Licker, Marc;
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Reproducibility of science and developmental anaesthesia neurotoxicity: a tale of two citiesVutskits, Laszlo; Sall, J W;
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Reproducibility of transpulmonary thermodilution cardiac output measurements in clinical practice: a systematic reviewGiraud, Raphaël; Siegenthaler, Nils; Merlani, Paolo; Bendjelid, Karim;
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Risk factors for peripheral nerve injuries following neuraxial labour analgesia: a nested case-control studyHaller, Guy Serge Antoine; Pichon, I; Gay, F-O; Savoldelli, Georges Louis;
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Risk factors of postcardiotomy ventricular dysfunction in moderate-to-high risk patients undergoing open-heart surgeryEllenberger, Christoph; Sologashvili, Tornike; Cikirikcioglu, Mustafa; Verdon, Gabriel; ... Licker, Marc
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Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective studyLloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer, Caroline Flora; ... Besson, Marie
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Short-term preoperative exercise therapy does not improve long-term outcome after lung cancer surgery: a randomized controlled study†Karenovics, Wolfram; Licker, Marc; Ellenberger, Christoph; Christodoulou, Michel; ... Triponez, Frédéric
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Suspected Arterial Vasospasm in Femoro-Femoral Veno-Arterial Extracorporeal Life SupportArroyo, Diego; Bendjelid, Karim; Robert-Ebadi, Helia; Rigamonti, Fabio; ... Giraud, Raphaël
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The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell TransplantationUppugunduri, Chakradhara Rao S; Storelli, Flavia; Mlakar, Vid; Huezo-Diaz Curtis, Patricia; ... Ansari Djaberi, Marc Georges
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The farming environment protects mice from allergen-induced skin contact hypersensitivityFrossard, C P; Lazarevic, Vladimir; Gaia, Nadia; Leo, Stefano; ... Eigenmann, Philippe
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The new FDA drug safety communication on the use of general anesthetics in young children: what should we make of it?Davidson, Andrew; Vutskits, Laszlo;
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The physiology of submaximal exercise: The steady state conceptFerretti, Guido; Fagoni, Nazzareno; Taboni, Anna; Bruseghini, Paolo; Vinetti, Giovanni
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The use of the oesophageal Doppler in perioperative medicine: new opportunities in research and clinical practiceBolen Pinto, Bernardo; Atlas, Glen; Geerts, Bart F; Bendjelid, Karim;
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Thinking, fast and slow: highlights from the 2016 BJA seminar on anaesthetic neurotoxicity and neuroplasticitySoriano, S G; Vutskits, Laszlo; Jevtovic-Todorovic, V; Hemmings, H C;
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Update on developmental anesthesia neurotoxicityVutskits, Laszlo; Davidson, Andrew;
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Usefulness of near-infrared angiography for identifying the intersegmental plane and vascular supply during video-assisted thoracoscopic segmentectomyGuigard, Sébastien; Triponez, Frédéric; Bedat, Benoît; Vidal Fortuny, Jordi; ... Karenovics, Wolfram
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Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized MedicineMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
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Validation of the French version of the Edmonton Symptom Assessment System (F-ESAS)Pautex, Sophie Marie; Vayne-Bossert, Petra; Bernard, Mathieu; Beauverd, Michel; ... Escher, Monica
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Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the futureDarwich, A S; Ogungbenro, K; Vinks, A A; Powell, J R; ... Rostami-Hodjegan, A

Professional Articles

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Grundlagen und praktische Hinweise fur pharmakogenetische TestsBaumann, Pierre; Amstutz, Ursula; Jetter, Alexander; Samer, Caroline Flora; Ansari Djaberi, Marc Georges
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Notions de base et aspects pratiques à propos de tests pharmacogénétiquesBaumann, Pierre; Amstutz, ursula; Jetter, Alexander; Samer, Caroline Flora; Ansari Djaberi, Marc Georges

Doctoral Thesis

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CYP450-mediated drug-drug interactions: towards prediction and informed dose recommendation using physiologically-based pharmacokinetic (PBPK) modelingMarsousi, Niloufar;

Privat-docent Thesis

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Cytochromes P450 activity and functionality: biomarker of drug response and valuable tool for Precision MedicineSamer, Caroline Flora;
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Drug interactions in the context of neuromuscular blockade: clinical implications and safety issuesCzarnetzki, Christoph;
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Health technology assessment: a framework for economic evaluations in policy guidance and medical managementGirardin, François;
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Role of systematic reviews in the identification and prevention of poor quality research and scientific misconduct: random reflections based on anaesthesiologic casesElia, Nadia;
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