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Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic beta-cell activation Wiederkehr, Andreas; Park, Kyu-Sang; Dupont, Olivier; Demaurex, Nicolas; ... Wollheim, Claes 2009
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Labeling of Bifidobacterium longum cells with 13C-substituted leucine for quantitative proteomic analyses Coute, Yohann; Hernandez, Céline; Appel, Ron David; Sanchez, Jean-Charles; Margolles, Abelardo 2007
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Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line Wang, Haiyan; Maechler, Pierre; Hagenfeldt-Johansson, Kerstin Arlette; Wollheim, Claes 1998
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Sequence requirements for proinsulin processing at the B-chain/C-peptide junction Kaufmann, J. E.; Irminger, Jean-Claude; Halban, Philippe A. 1995
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The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide Rhodes, C. J.; Halban, Philippe A. 1988
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Proinsulin modified by analogues of arginine and lysine is degraded rapidly in pancreatic B-cells Halban, Philippe A.; Amherdt, M.; Orci, Lelio; Renold, A. E. 1984
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Influence of glucose on insulin handling by rat islets in culture. A reflection of integrated changes in insulin biosynthesis, release, and intracellular degradation Halban, Philippe A.; Renold, A. E. 1983
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Inhibition of proinsulin to insulin conversion in rat islets using arginine and lysine analogs. Lack of effect on rate of release of modified products Halban, Philippe A. 1982
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Differential rates of release of newly synthesized and of stored insulin from pancreatic islets Halban, Philippe A. 1982
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Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content Halban, Philippe A.; Wollheim, Claes 1980