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Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism Roomp, Kirsten; Kristinsson, Hjalti; Schvartz, Domitille; Ubhayasekera, Kumari; ... Bergsten, Peter 2017
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Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production Dalmas, Elise; Lehmann, Frank M; Dror, Erez; Wueest, Stephan; ... Donath, Marc Y 2017
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Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose Johnston, Natalie R; Mitchell, Ryan K; Haythorne, Elizabeth; Pessoa, Maria Paiva; ... Hodson, David J 2016
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A pancreatic clock times insulin release Dibner, Charna; Schibler, Ueli 2015
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Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function Modi, Honey; Jacovetti, Cecile; Tarussio, David; Metref, Salima; ... Thorens, Bernard 2015
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Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells Rutti Roch, Sabine; Arous, Caroline; Nica, Alexandra C; Kanzaki, Makoto; ... Bouzakri, Karim 2014
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A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic islets Sileno, Sara; D'Oria, Valentina; Stucchi, Riccardo; Alessio, Massimo; ... Massa, Ornella 2014
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DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets Hall, Elin; Dayeh, Tasnim; Kirkpatrick, Clare; Wollheim, Claes; ... Ling, Charlotte 2013
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Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release Spégel, Peter; Sharoyko, Vladimir V; Goehring, Isabel; Danielsson, Anders P H; ... Mulder, Hindrik 2013
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Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction Bugliani, Marco; Liechti, Robin; Cheon, Hwanju; Suleiman, Mara; ... Marchetti, Piero 2013
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Nogo-A downregulation improves insulin secretion in mice Bonal, Claire Brune; Baronnier Caffe, Delphine; Pot, Caroline; Benkhoucha, Mahdia; ... Herrera, Pedro Luis 2013
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Hepatic glucose sensing is required to preserve β cell glucose competence Seyer, Pascal; Vallois, David; Poitry-Yamate, Carole; Schutz, Frédéric; ... Thorens, Bernard 2013
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Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase Vetterli, Laurene Marine; Carobbio, Stefania; Pournourmohammadi, Shirin; Martin-Del-Rio, Rafael; ... Maechler, Pierre 2012
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NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion Li, Ning; Li, Bin; Brun, Thierry; Deffert-Delbouille, Christine; ... Maechler, Pierre 2012
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The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in mice Zhang, Ye; Xie, Zhifang; Zhou, Luting; Li, Ling; ... Zhang, Weiping J 2012
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Modulation of neuronal pentraxin 1 expression in rat pancreatic β-cells submitted to chronic glucotoxic stress Schvartz, Domitille; Coute, Yohann; Brunner, Yannick; Wollheim, Claes; Sanchez, Jean-Charles 2012
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Pyruvate dehydrogenase E1α phosphorylation is induced by glucose but does not control metabolism-secretion coupling in INS-1E clonal β-cells Akhmedov, Dmitry; De Marchi, Umberto; Wollheim, Claes; Wiederkehr, Andreas 2012
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Mitochondrial signals drive insulin secretion in the pancreatic β-cell Wiederkehr, Andreas; Wollheim, Claes 2012
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AEB071 (sotrastaurin) does not exhibit toxic effects on human islets in vitro, nor after transplantation into immunodeficient mice Merani, Shaheed; McCall, Michael; Pawlick, Rena L; Edgar, Ryan L; ... Shapiro, A M James 2011
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Non-invasive imaging of ferucarbotran labeled INS-1E cells and rodent islets in vitro and in transplanted diabetic rats Auer, Veronika J; Bucher, Julian; Schremmer-Danninger, Elisabeth; Paulmurugan, Ramasamy; ... Berger, Frank 2011
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