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Losartan, an angiotensin II type 1 receptor blocker, protects human islets from glucotoxicity through the phospholipase C pathway Madec, Anne-Marie; Cassel, Roméo; Dubois, Séverine; Ducreux, Sylvie; ... Thivolet, Charles 2013
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Context-specific α- to-β-cell reprogramming by forced Pdx1 expression Yang, Yu-Ping; Thorel, Fabrizio; Boyer, Daniel F; Herrera, Pedro Luis; Wright, Christopher V E 2011
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Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress Kirkpatrick, Clare; Wiederkehr, Andreas; Baquie, Mathurin; Akhmedov, Dmitry; ... Wollheim, Claes 2011
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Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets Yang, B T; Dayeh, T A; Kirkpatrick, Clare; Taneera, J; ... Ling, C 2011
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In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice Hu He, Kai Hui; Lorenzo, Petra I; Brun, Thierry; Jimenez Moreno, Carmen M; ... Gauthier, Benoît 2011
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The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression Ait-Lounis, Aouatef; Bonal, Claire; Seguin-Estevez, Queralt; Schmid, C. D.; ... Reith, Walter 2010
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Glucose inhibits angiogenesis of isolated human pancreatic islets Dubois, S.; Madec, A. M.; Mesnier, A.; Armanet, Mathieu Pierre Jean; ... Thivolet, Ch 2010
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Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression Serre Beinier, Véronique; Bosco, Domenico; Zulianello, Laurence; Charollais, Anne; ... Meda, Paolo 2009
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The Fas pathway is involved in pancreatic beta cell secretory function Schumann, D. M.; Maedler, Kathrin; Franklin, Isobel; Konrad, Daniel; ... Donath, M. Y. 2007
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Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation Mouche, Sarah; Mkaddem, Sanae Ben; Wang, Wei; Katic, Masa; ... Szanto, Ildiko 2007