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 TitleAuthors / EditorsDate
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Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer Hany, Dina; Zoetemelk, Marloes; Bhattacharya, Kaushik; Nowak-Sliwinska, Patrycja; Picard, Didier 2023
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Phosphorylation of the Hsp90 Co-Chaperone Hop Changes its Conformational Dynamics and Biological Function Castelli, Matteo; Bhattacharya, Kaushik; Abboud, Ernest; Serapian, Stefano A.; ... Colombo, Giorgio 2023
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Hyperactivation of MAPK Induces Tamoxifen Resistance in SPRED2-Deficient ERα-Positive Breast Cancer Vafeiadou, Vasiliki; Hany, Dina; Picard, Didier 2022
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Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis Mohammadi Ghahhari, Nastaran; Sznurkowska, Magdalena K.; Hulo, Nicolas; Bernasconi, Lilia; ... Picard, Didier 2022
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Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life Bhattacharya, Kaushik; Maiti, Samarpan; Zahoran, Szabolcs; Weidenauer, Lorenz; ... Picard, Didier 2022
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Cytosolic Hsp90 Isoform-Specific Functions and Clinical Significance Maiti, Samarpan; Picard, Didier 2022
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The Mitochondrial HSP90 Paralog TRAP1: Structural Dynamics, Interactome, Role in Metabolic Regulation, and Inhibitors Joshi, Abhinav; Ito, Takeshi; Picard, Didier; Neckers, Len 2022
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H90-10 single-chain antibody recognizes Hsp90beta by immunoprecipitation and Western blotting Abboud, Ernest; Bernasconi, Lilia; Picard, Didier 2021
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Cooperative interaction between ERα and ZEB1 in breast cancer mediates global reprogramming of ERα signaling towards a metastatic phenotype during early EMT Mohammadi Ghahhari, Nastaran 2021
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The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis Joshi, Abhinav; Dai, Li; Liu, Yanxin; Lee, Jungsoon; ... Picard, Didier 2020
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Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins Mazaira, Gisela I.; Echeverria, Pablo; Galigniana, Mario D. 2020
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The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation Bhattacharya, Kaushik; Weidenauer, Lorenz; Luengo, Tania Morán; Pieters, Ellis C.; ... Picard, Didier 2020
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The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity Echeverria, Pablo Christian; Bhattacharya, Kaushik; Joshi, Abhinav; Wang, Tai; Picard, Didier 2019
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The HSP90 paralog TRAP1 oligomerizes into an OXPHOSregulated protein complex that may be essential for maintaining mitochondrial metabolic homeostasis Joshi, Abhinav 2019
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Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling Segala, Grégory; Bennesch, Marcela; Mohammadi Ghahhari, Nastaran; Pandey, Deo Prakash; ... Picard, Didier 2019
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Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development Neckers, Len; Blagg, Brian; Haystead, Timothy; Trepel, Jane B.; ... Picard, Didier 2018
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Dependence of ERα on phosphorylated CREB1 relies on interaction and corecruitment to target sites Berto, Mélissa 2018
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Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes Bhattacharya, Kaushik; Bernasconi, Lilia; Picard, Didier 2018
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ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1 Berto, Mélissa; Jean, Valérie; Zwart, Wilbert; Picard, Didier 2018
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Dendrogenin A drives LXR to trigger lethal autophagy in cancers Segala, Grégory; David, Marion; de Medina, Philippe; Poirot, Mathias C.; ... Silvente-Poirot, Sandrine 2017
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