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Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation Wallin, Tina; Ma, Zuheng; Ogata, Hirotaka; Jørgensen, Ingrid Hals; ... Björklund, Anneli 2010
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AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF. Kilbride, Seán M; Farrelly, Angela M; Bonner, Caroline; Ward, Manus W; ... Prehn, Jochen H M 2010
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PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression Gauthier, Benoît; Wiederkehr, Andreas; Baquie, Mathurin; Dai, Chunhua; ... Wollheim, Claes 2009
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System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock Kornmann, Benoît; Schaad, Olivier; Bujard, Hermann; Takahashi, Joseph S.; Schibler, Ulrich 2007
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Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species Produit-Zengaffinen, Nathalie; Davis-Lameloise, N.; Perreten, H.; Becard, D.; ... Assimacopoulos, Françoise 2007
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Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells Wang, Haiyan; Iezzi, M.; Theander, Sten; Antinozzi, P. A.; ... Wollheim, Claes 2005
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Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death Wobser, Hella; Düssmann, Heiko; Kögel, Donat; Wang, Haiyan; ... Prehn, Jochen H M 2002
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Modulation of myosin A expression by a newly established tetracycline repressor-based inducible system in Toxoplasma gondii Meissner, Markus; Brecht, Susan; Bujard, Hermann; Soldati-Favre, Dominique 2001
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Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion Wang, Haiyan; Maechler, Pierre; Antinozzi, Peter; Hagenfeldt-Johansson, Kerstin Arlette; Wollheim, Claes 2000