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Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase Andersson, Lotta E.; Shcherbina, Liliya; Al-Majdoub, Mahmoud; Vishnu, Neelanjan; ... Spégel, Peter 2018
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Sulforaphane improves disrupted ER-mitochondria interactions and suppresses exaggerated hepatic glucose production Tubbs, Emily; Axelsson, Annika S; Vial, Guillaume; Wollheim, Claes; ... Rosengren, Anders H 2018
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Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes Solimena, Michele; Schulte, Anke M; Marselli, Lorella; Ehehalt, Florian; ... Marchetti, Piero 2018
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Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes Ly, Luong Dai; Xu, Shanhua; Choi, Seong-Kyung; Ha, Chae-Myeong; ... Park, Kyu-Sang 2017
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Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes Shcherbina, L.; Edlund, A.; Esguerra, J.L.S.; Abels, M.; ... Wierup, N. 2017
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Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes Axelsson, Annika S; Tubbs, Emily; Mecham, Brig; Chacko, Shaji; ... Rosengren, Anders H 2017
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Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes Axelsson, A. S.; Mahdi, T.; Nenonen, H. A.; Singh, T.; ... Rosengren, A. H. 2017
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Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell Ofori, Jones K.; Salunkhe, Vishal A.; Bagge, Annika; Vishnu, Neelanjan; ... Esguerra, Jonathan L. S. 2017
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Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes Prasad, Rashmi B; Lessmark, Anna; Almgren, Peter; Kovacs, Györgyi; ... Groop, Leif 2016
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Microbial signals to the brain control weight Trajkovski, Mirko; Wollheim, Claes 2016
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Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high phosphate-induced mitochondrial oxidative stress and defective insulin secretion Nguyen, Tuyet Thi; Quan, Xianglan; Xu, Shanhua; Das, Ranjan; ... Park, Kyu-Sang 2016
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Essential Role of Mitochondrial Ca2+ Uniporter in the Generation of Mitochondrial pH Gradient and Metabolism-Secretion Coupling in Insulin-releasing Cells Quan, Xianglan; Nguyen, Tuyet Thi; Choi, Seong-Kyung; Xu, Shanhua; ... Park, Kyu-Sang 2015
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Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia Taneera, J.; Fadista, J.; Ahlqvist, E; Atac, D.; ... Groop, L. 2015
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Inhibition of the malate–aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion Stamenkovic, Jelena A.; Andersson, Lotta E.; Adriaenssens, Alice E.; Bagge, Annika; ... Spégel, Peter 2015
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Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs? Wollheim, Claes; Maechler, Pierre 2015
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Mitochondrial oxidative stress mediates high-phosphate-induced secretory defects and apoptosis in insulin-secreting cells Nguyen, Tuyet Thi; Quan, Xianglan; Hwang, Kyu-Hee; Xu, Shanhua; ... Park, Kyu-Sang 2015
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Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion Dayeh, Tasnim; Volkov, Petr; Salö, Sofia; Hall, Elin; ... Ling, Charlotte 2014
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Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism Fadista, João; Vikman, Petter; Laakso, Emilia Ottosson; Mollet, Inês Guerra; ... Groop, Leif 2014
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TCF7L2 is a master regulator of insulin production and processing Zhou, Yuedan; Park, Soo-Young; Su, Jing; Bailey, Kathleen; ... Hansson, Ola 2014
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Mitochondrial phosphate transport during nutrient stimulation of INS-1E insulinoma cells Quan, Xianglan; Das, Ranjan; Xu, Shanhua; Cline, Gary W; ... Park, Kyu-Sang 2013
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