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The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in mitochondrial metabolic homeostasis Joshi, Abhinav; Dai, Li; Liu, Yanxin; Lee, Jungsoon; ... Picard, Didier 2020
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Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial Pezzatti, Julian; Boccard, Julien; Codesido, Santiago; Gagnebin, Yoric; ... Rudaz, Serge 2020
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The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity Echeverria, Pablo Christian; Bhattacharya, Kaushik; Joshi, Abhinav; Wang, Tai; Picard, Didier 2019
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Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling Segala, Grégory; Bennesch, Marcela; Mohammadi Ghahhari, Nastaran; Pandey, Deo Prakash; ... Picard, Didier 2019
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AI179 single-chain antibody recognizes the Myc tag by Western blotting Keszei, Zsofia; Picard, Didier 2019
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AF291 and AE391 single-chain antibodies recognize the HA tag by Western blotting Keszei, Zsofia; Picard, Didier 2019
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A scoring approach for multi-platform acquisition in metabolomics Pezzatti, Julian; Gonzalez Ruiz, Victor; Codesido Sanchez, Santiago; Gagnebin, Yoric; ... Rudaz, Serge 2019
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Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes Bhattacharya, Kaushik; Bernasconi, Lilia; Picard, Didier 2018
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ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1 Berto, Mélissa; Jean, Valérie; Zwart, Wilbert; Picard, Didier 2018
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Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development Neckers, Len; Blagg, Brian; Haystead, Timothy; Trepel, Jane B.; ... Picard, Didier 2018
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Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model Vartholomaiou, Evangelia; Madon-Simon, Marta; Hagmann, Stéphane; Muhlebach, Guillaume; ... Picard, Didier 2017
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Dendrogenin A drives LXR to trigger lethal autophagy in cancers Segala, Grégory; David, Marion; de Medina, Philippe; Poirot, Mathias C.; ... Silvente-Poirot, Sandrine 2017
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Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson’s disease Fitzgerald, Julia C.; Zimprich, Alexander; Carvajal Berrio, Daniel A.; Schindler, Kevin M.; ... Krüger, Rejko 2017
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H2B monoubiquitination: t'ub or not t'ub for inducible enhancers Segala, Grégory; Picard, Didier 2017
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Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol Abla, Nada; Bashyam, Sridevi; Charman, Susan A.; Greco, Béatrice; ... Spangenberg, Thomas 2017
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A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells Pupo, Marco; Bodmer, Alexandre; Berto, Mélissa; Maggiolini, Marcello; ... Picard, Didier 2017
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Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23 Madon-Simon, Marta; Grad, Iwona; Bayo, Pilar; Pérez, Paloma; Picard, Didier 2017
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Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry Wider, Diana; Picard, Didier 2017
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LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP Bennesch, Marcela; Segala, Grégory; Wider, Diana; Picard, Didier 2016
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Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers Segala, Grégory; Bennesch, Marcela; Pandey, Deo Prakash; Hulo, Nicolas; Picard, Didier 2016
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