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Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef 2018
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Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites Marsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora 2018
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Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef 2017
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Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future Darwich, A S; Ogungbenro, K; Vinks, A A; Powell, J R; ... Rostami-Hodjegan, A 2017
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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases Romand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge 2017
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CYP450-mediated drug-drug interactions: towards prediction and informed dose recommendation using physiologically-based pharmacokinetic (PBPK) modeling Marsousi, Niloufar 2017
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Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells Marsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef 2016
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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach Marsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef 2016
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Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic Model Marsousi, Niloufar; Daali, Youssef; Rudaz, Serge; Almond, L; ... Samer, Caroline Flora 2014