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Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutation Silachev, Denis; Koval, Alexey; Savitskiy, Mikhail; Padmasola, Guru Prasad; ... Katanaev, Vladimir 2022
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Chemoenzymatic synthesis of complex phenylpropanoid derivatives by the Botrytis cinerea secretome and evaluation of their wnt inhibition activity Huber, Robin; Marcourt, Laurence; Koval, Alexey; Schnee, Sylvain; ... Ferreira Queiroz, Emerson 2022
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Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growth Miete, Cezanne; Solis, Gonzalo; Koval, Alexey; Brückner, Martina; ... Bernkopf, Dominic B 2022
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Chemoenzymatic synthesis of original stilbene dimers possessing wnt inhibition activity in triple-negative breast cancer cells using the enzymatic secretome of Botrytis cinerea pers Huber, Robin; Koval, Alexey; Marcourt, Laurence; Heritier, Margaux; ... Ferreira Queiroz, Emerson 2022
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Wnt-pathway inhibitors with selective activity against triple-negative breast cancer: from thienopyrimidine to quinazoline inhibitors Boudou, Cédric; Mattio, Luce; Koval, Alexey; Soulard, Valentin; Katanaev, Vladimir 2022
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Restoration of the GTPase activity and cellular interactions of Gαo mutants by Zn2+ in GNAO1 encephalopathy models Larasati, Yonika Arum; Savitskiy, Mikhail; Koval, Alexey; Solis, Gonzalo; ... Katanaev, Vladimir 2022
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Short stature and combined immunodeficiency associated with mutations in RGS10 Chinn, Ivan K.; Xie, Zhihui; Chan, Eunice C.; Nagata, Bianca M.; ... Druey, Kirk M. 2021
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Optimization of the clofazimine structure leads to a highly water-soluble C3-aminopyridinyl riminophenazine endowed with improved anti-Wnt and anti-cancer activity in vitro and in vivo Koval, Alexey; Bassanini, Ivan; xu, Jiabin; Tonelli, Michele; ... Katanaev, Vladimir 2021
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Mining natural compounds to target WNT signaling: land and sea tales Katanaev, Vladimir; Blagodatski, Artem; xu, Jiabin; Khotimchenko, Yuri; Koval, Alexey 2021
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Pediatric encephalopathy: cinical, biochemical and cellular insights into the role of Gln52 of GNAO1 and GNAI1 for the dominant disease Solis, Gonzalo; Kozhanova, Tatyana V.; Koval, Alexey; Zhilina, Svetlana S.; ... Katanaev, Vladimir 2021
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Unlocking the Wnt pathway: therapeutic potential of selective targeting FZD7 in cancer Larasati, Yonika Arum; Boudou, Cédric; Koval, Alexey; Katanaev, Vladimir 2021
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A cytotoxic porphyrin from North Pacific brittle star Ophiura sarsii Klimenko, Antonina; Huber, Robin; Marcourt, Laurence; Chardonnens, Estelle; ... Katanaev, Vladimir 2021
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Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells Seguin, Laetitia; Odouard, Soline; Corlazzoli, Francesca; Al Haddad, Sarah; ... Cosset, Erika 2021
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Isolation and identification of isocoumarin derivatives with specific inhibitory activity against wnt pathway and metabolome characterization of lasiodiplodia venezuelensis Pellissier, Léonie; Koval, Alexey; Marcourt, Laurence; Ferreira Queiroz, Emerson; ... Wolfender, Jean-Luc 2021
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Beyond TNBC: repositioning of clofazimine against a broad range of Wnt-dependent cancers xu, Jiabin; Koval, Alexey; Katanaev, Vladimir 2020
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Generation of stilbene antimicrobials against multiresistant strains of Staphylococcus aureus through biotransformation by the enzymatic secretome of Botrytis cinerea Righi, Davide; Huber, Robin; Koval, Alexey; Marcourt, Laurence; ... Ferreira Queiroz, Emerson 2020
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A high-throughput assay pipeline for specific targeting of frizzled GPCRs in cancer Shaw, Holly Victoria; Koval, Alexey; Katanaev, Vladimir 2019
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Targeting the Wnt signalling pathway in cancer: prospects and perils Shaw, Holly Victoria; Koval, Alexey; Katanaev, Vladimir 2019
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Towards the first targeted therapy for triple-negative breast cancer: Repositioning of clofazimine as a chemotherapy-compatible selective Wnt pathway inhibitor Ahmed, Kamal; Koval, Alexey; Xu, Jiabin; Bodmer, Alexandre; Katanaev, Vladimir 2019
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Chemo-diversification of plant extracts using a generic bromination reaction and monitoring by metabolite profiling Righi, Davide; Marcourt, Laurence; Koval, Alexey; Ducret, Verena; ... Ferreira Queiroz, Emerson 2019
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